Abstract: Provided herein are compounds useful for the treatment of various proliferative diseases. These compounds, as well as pharmaceutically acceptable salts thereof may be formulated in pharmaceutical compositions, and may be used in methods of treatment and/or prophylaxis of proliferative diseases, including cancer, and more specifically, pancreatic cancer.

Abstract: Disclosed herein are methods, pharmaceutical compositions, and vaccines for modulating an immune response. Also disclosed herein are methods, pharmaceutical compositions, and vaccines for inducing an immune response.

Abstract: A apparatus for fault detection for use in an electric aircraft is disclosed herein. The apparatus includes a battery module with a plurality of battery cells, a plate extending along the row of cells, insulation between the plate and the plurality of cells, a sensor configured to detect a potential signal, and a controller communicatively connected to the sensor. The controller is configured to receive the potential signal and determine a fault.

Abstract: A system including a battery module configured for use in an electric aircraft includes at least a battery cell and a battery module casing. The at least a battery cell includes at least a pair of cell tabs and at least a conductor. The battery module casing includes at least a lithiophobic surface with an ejecta barrier and at least a nonlithiphobic surface that is configured to vent the cell ejecta. The battery module casing closely matches the dimensions of the battery cell.

Abstract: A apparatus for fault detection for use in an electric aircraft is disclosed herein. The apparatus includes a battery module with a plurality of battery cells, a plate extending along the row of cells, insulation between the plate and the plurality of cells, a sensor configured to detect a potential signal, and a controller communicatively connected to the sensor. The controller is configured to receive the potential signal and determine a fault.

Abstract: A vehicle traction battery assembly including a pair of battery cells and a busbar is provided. Each of the battery cells may include a terminal and one or more locating features. The busbar may span between the cells and define a pair of arms each having a member sized to at least partially interlock with the one or more locating features. The busbar may span between the cells such that the busbar covers at least a portion of upper surfaces defined by each of the cells. At least one of the terminal apertures may be spaced in between outer edges of the respective arms such that a first and second surface area provide space sufficient for weld spots.

Abstract: Provided herein are compounds useful for the treatment of various proliferative diseases. These compounds, as well as pharmaceutically acceptable salts thereof may be formulated in pharmaceutical compositions, and may be used in methods of treatment and/or prophylaxis of proliferative diseases, including cancer, and more specifically, pancreatic cancer.

Abstract: An exemplary battery assembly includes a first terminal holder, and a terminal at least partially surrounded by the first terminal holder. The first terminal holder includes a locating feature to position the first terminal holder relative to a second terminal holder.

Abstract: A vehicle traction battery assembly including a pair of battery cells and a busbar is provided. Each of the battery cells may include a terminal and one or more locating features. The busbar may span between the cells and define a pair of arms each having a member sized to at least partially interlock with the one or more locating features. The busbar may span between the cells such that the busbar covers at least a portion of upper surfaces defined by each of the cells. At least one of the terminal apertures may be spaced in between outer edges of the respective arms such that a first and second surface area provide space sufficient for weld spots.

Abstract: A vehicle traction battery assembly including a pair of battery cells and a busbar is provided. Each of the battery cells may include a terminal and one or more locating features. The busbar may span between the cells and define a pair of arms each having a member sized to at least partially interlock with the one or more locating features. The busbar may span between the cells such that the busbar covers at least a portion of upper surfaces defined by each of the cells. At least one of the terminal apertures may be spaced in between outer edges of the respective arms such that a first and second surface area provide space sufficient for weld spots.

Abstract: A battery assembly includes a plurality of battery cells and a support structure positioned about the plurality of battery cells. The support structure includes at least one sidewall and the at least one sidewall includes a first flange that extends adjacent a top surface of each of the plurality of battery cells and a second flange that extends beyond a bottom surface of each of the plurality of battery cells.

Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:

Abstract: An assembly according to an exemplary aspect of the present disclosure includes, among other things, a plurality of battery cells and a bus bar assembly received over the plurality of battery cells. The bus bar assembly comprises a housing, a bus bar received within the housing and a retention device disengageable from the bus bar to move the bus bar between a first position and a second position.

Abstract: A bus bar assembly according to an exemplary aspect of the present disclosure includes, among other things, a plurality of battery cells and a bus bar assembly that electrically connects the plurality of battery cells. The bus bar assembly includes a flexible cable, a voltage sense lead connected to the flexible cable, and a bus bar connected to the voltage sense lead.

Abstract: A vehicle including a pair of spaced apart battery cell arrays, a pair of sub-structures configured to retain the arrays, and a thermal plate assembly disposed between the arrays is provided. Each of the sub-structures may include opposing endplates and opposing upper and lower sidewalls secured to the endplates and each having a flange extending toward and overlapping with the respective flange of the other sub-structure to join the sub-structures without mechanical fastening. The thermal plate assembly may be disposed between the overlapping flanges and the arrays to form a sandwich formation. The thermal plate assembly may include at least one thermal interface component disposed on a side of a thermal plate, and in contact with a portion of at least one of the battery cell arrays.

Abstract: A battery assembly includes a plurality of battery cells and a support structure positioned about the plurality of battery cells. The support structure includes at least one sidewall and the at least one sidewall includes a first flange that extends adjacent a top surface of each of the plurality of battery cells and a second flange that extends beyond a bottom surface of each of the plurality of battery cells.

Abstract: A traction battery assembly for a vehicle includes an array of cells stacked on a tray. The array of cells defines opposing longitudinal sides and opposing lateral sides. First and second L-shaped components are attached to the tray. Each of the components includes an end wall and a sidewall that are integrally formed to define a substantially 90° corner. The first and second components are attached together such that each of the sidewalls is disposed adjacent one of the longitudinal sides and each of the end walls is disposed adjacent one of the lateral sides to form a housing around the tray that has an open top and an open bottom.

Abstract: A battery assembly according to an exemplary aspect of the present disclosure includes, among other things, a plurality of battery cells and a support structure positioned about the plurality of battery cells. The support structure includes at least one sidewall and the at least one sidewall includes a first flange that extends adjacent a top surface of each of the plurality of battery cells and a second flange that extends beyond a bottom surface of each of the plurality of battery cells.

Abstract: An assembly according to an exemplary aspect of the present disclosure includes, among other things, a plurality of battery cells and a bus bar assembly received over the plurality of battery cells. The bus bar assembly comprises a housing, a bus bar received within the housing and a retention device disengageable from the bus bar to move the bus bar between a first position and a second position.

Abstract: A vehicle traction battery assembly including a pair of battery cells and a busbar is provided. Each of the battery cells may include a terminal and one or more locating features. The busbar may span between the cells and define a pair of arms each having a member sized to at least partially interlock with the one or more locating features. The busbar may span between the cells such that the busbar covers at least a portion of upper surfaces defined by each of the cells. At least one of the terminal apertures may be spaced in between outer edges of the respective arms such that a first and second surface area provide space sufficient for weld spots.