Abstract: The differential expression of select miRNA in plasma and bile among patients with PDAC, chronic pancreatitis (CP), and controls were measured. Patients (n=215) with treatment-naïve PDAC (n=77), CP with bile or pancreatic duct pathology (n=67), and controls (n=71) that had been prospectively enrolled in a Pancreatobiliary Disease Biorepository at the time of endoscopic retrograde cholangiopancreatography (ERCP) or endoscopic ultrasound (EUS) were identified. Controls were patients with choledocholithiasis but normal pancreata. The sample was separated into training (n=95) and validation (n=120) cohorts to establish and then test the performance of PDAC Signature Panels in diagnosing PDAC. The training cohort (n=95) included age-matched patients with CP and controls. Panels were derived from the differential expression of 10-candidate miRNA in plasma or bile.

Abstract: The differential expression of select miRNA in plasma and bile among patients with PDAC, chronic pancreatitis (CP), and controls were measured. Patients (n=215) with treatment-naïve PDAC (n=77), CP with bile or pancreatic duct pathology (n=67), and controls (n=71) that had been prospectively enrolled in a Pancreatobiliary Disease Biorepository at the time of endoscopic retrograde cholangiopancreatography (ERCP) or endoscopic ultrasound (EUS) were identified. Controls were patients with choledocholithiasis but normal pancreata. The sample was separated into training (n=95) and validation (n=120) cohorts to establish and then test the performance of PDAC Signature Panels in diagnosing PDAC. The training cohort (n=95) included age-matched patients with CP and controls. Panels were derived from the differential expression of 10-candidate miRNA in plasma or bile.

Abstract: A computer-implemented system and method for monitoring the status of an item subject to a lien, comprising receiving registration information associated with the item subject to the lien, including at least one identifier uniquely associated with the item. The registration information is stored in a record associated with the item within an item database. Data about the item is received over a communications network from at least one information source based on the unique identifier associated with the item. The received data is compared to the stored registration information to determine whether the status of the item has changed. The database record is updated to reflect a change in status of the item and a notification is automatically generated to a holder of the lien when the status of the item has changed.

Abstract: Disclosed is a system (100), method and computer program product for facilitating wireless transmission of email messages. The method on a wireless device (106) includes storing a user's email viewing interest profile (110) and receiving a first portion of a wirelessly transmitted email message. The method further includes wirelessly transmitting a request for transmission of a second portion of the wirelessly transmitted email message in response to determining that the stored user's email viewing interest profile (110) indicates a user's interest in receiving a second portion of the wirelessly transmitted email message. The stored user's email viewing interest profile (110) associates a measure of a user's viewing interest with key field information of an email message.