Patents by Inventor Stuart Soo-In Hwang

Stuart Soo-In Hwang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Estrogen receptor beta variants and methods of detection thereof
    Patent number: 6818758
    Abstract: The present invention is based on sequencing genomic DNA from human chromosome 6 and cDNAs to define the genomic structure of estrogen receptor beta genes and novel polymorphism in the estrogen receptor gene/protein. Such polymorphism can lead to a variety of disorders that are mediated/modulated by a variant estrogen receptor, such as a susceptibility to cancer, osteoporosis, cardiovascular disorder, etc. Based on this sequencing approach, the present invention provides genomic nucleotide sequences, cDNA sequences, amino acid sequences and sequence polymorphism in the ESR-beta genes, methods of detecting these sequences/polymorphism in a sample, methods of determining a risk of having or developing a disorder mediated by a variant estrogen receptor and methods of screening for compounds used to treat disorders mediated by a variant estrogen receptor.
    Type: Grant
    Filed: January 24, 2001
    Date of Patent: November 16, 2004
    Assignee: Applera Corporation
    Inventors: Francis Kalush, Michael J Cassel, Stuart Soo-In Hwang, Emily S Winn-Deen
  • ESTROGEN RECEPTOR BETA VARIANTS AND METHODS OF DETECTION THEREOF
    Publication number: 20040185439
    Abstract: The present invention is based on sequencing genomic DNA from human chromosome 6 and cDNAs to define the genomic structure of estrogen receptor beta genes and novel polymorphism in the estrogen receptor gene/protein. Such polymorphism can lead to a variety of disorders that are mediated/modulated by a variant estrogen receptor, such as a susceptibility to cancer, osteoporosis, cardiovascular disorder, etc. Based on this sequencing approach, the present invention provides genomic nucleotide sequences, CDNA sequences, amino acid sequences and sequence polymorphism in the ESR-beta genes, methods of detecting these sequences/polymorphism in a sample, methods of determining a risk of having or developing a disorder mediated by a variant estrogen receptor and methods of screening for compounds used to treat disorders mediated by a variant estrogen receptor.
    Type: Application
    Filed: January 24, 2001
    Publication date: September 23, 2004
    Applicant: PE CORPORATION (NY)
    Inventors: Francis Kalush, Michael J. Cassel, Stuart Soo-In Hwang, Emily S. Winn-Deen
  • Estrogen receptor alpha variants and methods of detection thereof
    Publication number: 20020123095
    Abstract: The present invention is based on sequencing genomic DNA from human chromosome 6 and cDNAs to define the genomic structure of estrogen receptor alpha genes and novel polymorphism/haplotypes in the estrogen receptor gene/protein. Such polymorphism/haplotypes can lead to a variety of disorders that are mediated/modulated by a variant estrogen receptor, such as a susceptibility to cancer, osteoporosis, cardiovascular disorder, etc. Based on this sequencing approach, the present invention provides genomic nucleotide sequences, cDNA sequences, amino acid sequences and sequence polymorphism/haplotypes in the ESR-alpha genes, methods of detecting these sequences/polymorphism/haplotypes in a sample, methods of determining a risk of having or developing a disorder mediated by a variant estrogen receptor and methods of screening for compounds used to treat disorders mediated by a variant estrogen receptor.
    Type: Application
    Filed: August 21, 2001
    Publication date: September 5, 2002
    Applicant: PE CORPORATION (NY)
    Inventors: Francis Kalush, Michael J. Cassel, Stuart Soo-In Hwang, Emily S. Winn-Deen