Patents by Inventor Stuart Trembly

Stuart Trembly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12193970
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Grant
    Filed: November 3, 2023
    Date of Patent: January 14, 2025
    Assignee: ZOLL Circulation, Inc.
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Publication number: 20240207089
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Application
    Filed: November 3, 2023
    Publication date: June 27, 2024
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Patent number: 11844722
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: December 19, 2023
    Assignee: ZOLL Circulation, Inc.
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Patent number: 11246747
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: February 15, 2022
    Assignee: Zoll Circulation, Inc.
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Publication number: 20210220166
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Application
    Filed: March 31, 2021
    Publication date: July 22, 2021
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Publication number: 20200268549
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Application
    Filed: December 18, 2019
    Publication date: August 27, 2020
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Patent number: 10548763
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: February 4, 2020
    Assignee: Zoll Circulation, Inc.
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Patent number: 10485481
    Abstract: A method for enhancing uptake of a therapeutic agent from the bloodstream of a patient into a disease site of the patient includes applying negative pressure to the disease site to form a pressure differential favorable for transport of the therapeutic agent from the bloodstream into the disease site. A system for enhancing uptake of therapeutic agent from the bloodstream of a patient into a disease site of the patient includes (a) a partial enclosure with edge configured to interface with an exposed surface, of the patient and overlying the disease site, to seal the partial enclosure to the exposed surface, and (b) a pump for evacuating air from the partial enclosure to produce a partial vacuum in the partial enclosure, to apply a negative pressure to the disease site so as to enhance uptake of the therapeutic agent into the disease site.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: November 26, 2019
    Assignee: THE TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: B. Stuart Trembly, Michael D. Nieskoski
  • Publication number: 20180153734
    Abstract: An implantable radially-porous, polymeric, scaffold device configured for insertion into and obstruct a Fallopian tube formed of a polymer such as collagen, nanocellulose, xanthan gum, konjac glucomannan, alginate, agar, agarose, chitin, chitosan, chitosan-alginate polylactic acid (PLA), polygultamic acid (PGA), polycaprolactone, or polydioxanone. The device is compressed and placed within a first end of an insertion tube adapted for insertion through the cervix into the Fallopian tube; the insertion tube having a plunger to expel the device from the tube. The method includes using the insertion tube containing the radially freeze-cast and freeze-dried implant. Under hysteroscopic guidance the tube is positioned in the Fallopian tube and the implant is expelled into the Fallopian tube. Epithelium of the Fallopian tube is disrupted; and ingrowth of cells into the implant is permitted.
    Type: Application
    Filed: December 6, 2017
    Publication date: June 7, 2018
    Inventors: Ulrike G.K. Wegst, Prajan Divakar, B. Stuart Trembly, P. Jack Hoopes, James D. Petryk, Daniel Santana
  • Publication number: 20170354534
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Application
    Filed: March 28, 2017
    Publication date: December 14, 2017
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Patent number: 9271789
    Abstract: A method for local heating includes placing first magnetic material in a first lumen, and a second magnetic material in a second lumen from the first magnetic material to a magnetically permeable rod, then applying alternating magnetic fields. The first lumen may be a fallopian tube. A method of occluding fallopian tubes uses a catheter to inject first magnetic material into the tubes, injecting second magnetic fluid into uterus, introducing a magnetically-permeable rod into vagina, positioning a second end of the rod over the fallopian tube and applying an alternating magnetic field to the first magnetic material to heat it. The method is performed with apparatus having a coil wound over a magnetically-permeable rod, a high frequency AC generator coupled to the coil, a first magnetic fluid capable of generating heat in an alternating magnetic field, and a second magnetically-permeable magnetic fluid capable of conducting magnetic fields through a lumen.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: March 1, 2016
    Assignee: The Trustees of Dartmouth College
    Inventor: B. Stuart Trembly
  • Patent number: 9131984
    Abstract: The present invention provides applicators for performing thermokeratoplasty. One embodiment of such applicators includes a pair of electrical conducting elements electrically separated by a selected distance and extending from a proximal end to a distal end. The electrical conducting elements define, at the distal end, a contact surface that is positionable at a cornea. At least one of the electrical conducting elements is divided into a plurality of discrete sections extending from the proximal end to the distal end. The discrete sections are selectively and separately actuated by a controller according to one or more variable characteristics to deliver energy to the cornea.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: September 15, 2015
    Assignee: The Trustees of Dartmouth College
    Inventor: B. Stuart Trembly
  • Publication number: 20140020689
    Abstract: A method for local heating includes placing first magnetic material in a first lumen, and a second magnetic material in a second lumen from the first magnetic material to a magnetically permeable rod, then applying alternating magnetic fields. The first lumen may be a fallopian tube. A method of occluding fallopian tubes uses a catheter to inject first magnetic material into the tubes, injecting second magnetic fluid into uterus, introducing a magnetically-permeable rod into vagina, positioning a second end of the rod over the fallopian tube and applying an alternating magnetic field to the first magnetic material to heat it. The method is performed with apparatus having a coil wound over a magnetically-permeable rod, a high frequency AC generator coupled to the coil, a first magnetic fluid capable of generating heat in an alternating magnetic field, and a second magnetically-permeable magnetic fluid capable of conducting magnetic fields through a lumen.
    Type: Application
    Filed: July 18, 2013
    Publication date: January 23, 2014
    Applicant: The Trustees of Dartmouth College
    Inventor: B. Stuart Trembly
  • Patent number: 8521302
    Abstract: Disclosed is a method and an apparatus for ablating biological tissues, in which a cannula is configured to affect biological tissue and a heat transmitting end-effecter is coupled to the cannula. A source of electromagnetic energy is provided via an electro-magnetic energy emitter and a wall of the heat transmitting end-effecter is made of an electromagnetic-energy-absorbing material that absorbs electromagnetic waves.
    Type: Grant
    Filed: January 12, 2009
    Date of Patent: August 27, 2013
    Assignee: Expanedoheat, L.L.C.
    Inventors: Gennady Kleyman, Annaniy Berenshteyn, Stuart Trembly
  • Patent number: 8396564
    Abstract: Apparatus and methods for the treatment of keratinized tissue infected with a pathogen are provided. In certain examples, electromagnetic energy, such as microwave energy, may be used in the treatment process to reduce the amount of or eliminate the pathogen from the keratinized tissue.
    Type: Grant
    Filed: September 21, 2007
    Date of Patent: March 12, 2013
    Assignee: Waverx, Inc.
    Inventors: Peter A Hoenig, B Stuart Trembly
  • Patent number: 8348936
    Abstract: A thermal treatment system with acoustic monitoring applies substantially constant electromagnetic energy superposed with pulsed electromagnetic energy to targeted tissue. The pulsed electromagnetic energy reacts with tissue to create an acoustic pressure wave within the tissue. The acoustic pressure wave is sensed by an acoustic sensor, and a sensor signal indicative of the acoustic pressure wave is generated and processed to determine changes in tissue composition.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: January 8, 2013
    Assignee: The Trustees of Dartmouth College
    Inventors: B. Stuart Trembly, Jason M. Dahlstrom
  • Patent number: 7744592
    Abstract: Apparatus and methods for the treatment of keratinized tissue infected with a pathogen are provided. In certain examples, electromagnetic energy, such as microwave energy, may be used in the treatment process to reduce the amount of or eliminate the pathogen from the keratinized tissue.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: June 29, 2010
    Assignee: Waverx, Inc.
    Inventors: Peter A. Hoenig, B. Stuart Trembly
  • Publication number: 20100160907
    Abstract: The present invention provides applicators for performing thermokeratoplasty. One embodiment of such applicators includes a pair of electrical conducting elements electrically separated by a selected distance and extending from a proximal end to a distal end. The electrical conducting elements define, at the distal end, a contact surface that is positionable at a cornea. At least one of the electrical conducting elements is divided into a plurality of discrete sections extending from the proximal end to the distal end. The discrete sections are selectively and separately actuated by a controller according to one or more variable characteristics to deliver energy to the cornea.
    Type: Application
    Filed: February 26, 2010
    Publication date: June 24, 2010
    Inventor: B. Stuart Trembly
  • Patent number: 7713268
    Abstract: The present invention provides applicators for performing thermokeratoplasty. One embodiment of such applicators includes two generally tubular electrical conducting elements coaxially disposed relative to one another and separated by an electrically insulating element having a selected thickness. At least a portion of each conducting tube is coated with an electrically insulating and thermally conductive material, e.g., anodized aluminum, so as to electrically insulate the conducting tubes from corneal tissue upon placement of the applicator on a subject's cornea while facilitating extraction of heat from the cornea.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: May 11, 2010
    Assignee: The Trustees of Dartmouth College
    Inventor: B. Stuart Trembly
  • Publication number: 20090182398
    Abstract: Disclosed is a method and an apparatus for ablating biological tissues, in which a cannula is configured to affect biological tissue and a heat transmitting end-effecter is coupled to the cannula. A source of electromagnetic energy is provided via an electro-magnetic energy emitter and a wall of the heat transmitting end-effecter is made of an electromagnetic-energy-absorbing material that absorbs electromagnetic waves.
    Type: Application
    Filed: January 12, 2009
    Publication date: July 16, 2009
    Applicant: EXPANDOHEAT, LLC
    Inventors: Gennady Kleyman, Annaniy Berenshteyn, Stuart Trembly