Patents by Inventor Styliani Tournaviti

Styliani Tournaviti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGONUCLEOTIDES TARGETING XBP1
    Publication number: 20230323421
    Abstract: The invention relates to antisense oligonucleotides which alter the splicing of XBP1 pre-mRNA. The antisense oligonucleotides have applications in enhancing the level and/or quality of protein expression in cells and in mammalian protein expression systems, such as heterologous protein expression systems, such as enhancing antibody expression in CHO cells. The antisense oligonucleotides also have applications in therapy, such as for the treatment or prevention of proteopathological diseases.
    Type: Application
    Filed: June 22, 2023
    Publication date: October 12, 2023
    Applicant: Roche Innovation Center Copenhagen A/S
    Inventors: Styliani TOURNAVITI, Jonas VIKESAA, Shan-Hua CHUNG
  • Method for producing antibodies using ovine B-cells and uses thereof
    Patent number: 11560420
    Abstract: Herein is reported a cultivation system for cultivating a pool of ovine B-cells or single deposited ovine B-cells in the presence of phorbol myristate acetate (PMA).
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: January 24, 2023
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Mirko Ritter, Styliani Tournaviti
  • METHOD FOR THE EXPRESSION OF AN ANTIBODY-MULTIMER-FUSION
    Publication number: 20220162295
    Abstract: Herein is reported a method for producing an antibody-multimer-fusion polypeptide comprising (a) an antibody heavy chain and an antibody light chain, and (b) a first fusion polypeptide comprising in N- to C-terminal direction a first part of a non-antibody multimeric polypeptide, an antibody heavy chain CH1 domain or an antibody light chain constant domain, an antibody hinge region, an antibody heavy chain CH2 domain and an antibody heavy chain CH3 domain, and a second fusion polypeptide comprising in N- to C-terminal direction the second part of the non-antibody multimeric polypeptide and an antibody light chain constant domain if the first polypeptide comprises an antibody heavy chain CH1 domain or an antibody heavy chain CH1 domain if the first polypeptide comprises an antibody light chain constant domain, wherein (i) the antibody heavy chain of (a) and the first fusion polypeptide of (b), (ii) the antibody heavy chain of (a) and the antibody light chain of (a), and (iii) the first fusion polypeptide of (
    Type: Application
    Filed: July 22, 2021
    Publication date: May 26, 2022
    Applicants: Hoffmann-La Roche Inc., Genentech, Inc.
    Inventors: Styliani Tournaviti, Shan-Hua Chung, Harald Duerr, Claudia Ferrara Koller, Amy Shen, Shahram Misaghi, Shuet Ming Yip
  • METHOD FOR PRODUCING ANTIBODIES USING OVINE B-CELLS AND USES THEREOF
    Publication number: 20180305441
    Abstract: Herein is reported a cultivation system for cultivating a pool of ovine B-cells or single deposited ovine B-cells in the presence of phorbol myristate acetate (PMA).
    Type: Application
    Filed: June 25, 2018
    Publication date: October 25, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Mirko Ritter, Styliani Tournaviti