Patents by Inventor Stylianos E. Antonarakis

Stylianos E. Antonarakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene defective in APECED and its use
    Patent number: 7785789
    Abstract: The present invention relates to a method for the diagnosis of a disease related to immune maturation and regulation of immune response towards self and nonself, comprising the steps of detecting in a biological specimen the presence of a DNA sequence comprising the sequence of SEQ ID NO:1.
    Type: Grant
    Filed: August 10, 2006
    Date of Patent: August 31, 2010
    Assignee: Finnish Immunotechnology Ltd.
    Inventors: Kai Krohn, Maarit Heino, Pärt Peterson, Hamish S Scott, Stylianos E. Antonarakis, Maria D. Lalioti, Nobuyoshi Shimizu, Jun Kudoh
  • Cystic fibrosis mutation cluster
    Patent number: 5407796
    Abstract: Four mutations have been found clustered in exon 11 of the CFTR (cystic fibrosis transmembrane conductance regulator) gene. These mutations occur within a set of amino acids highly conserved among ATP-dependent transport proteins. Humans can be tested to determine whether they carry one of these mutations using a number of methods and/or probes taught herein. Specifically the mutations include: Asn.sub.549, Asp.sub.551, Stop.sub.553, and Thr.sub.559.
    Type: Grant
    Filed: January 4, 1991
    Date of Patent: April 18, 1995
    Assignee: The Johns Hopkins University
    Inventors: Garry R. Cutting, Stylianos E. Antonarakis, Haig H. Kazazian, Jr.