Patents by Inventor Su Bin MOON

Su Bin MOON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED GUIDE RNA FOR OPTIMIZED CRISPR/CAS12F1 (CAS14A1) SYSTEM AND USE THEREOF
    Publication number: 20230416784
    Abstract: Provided is an engineered CRISPR/Cas12f1 (Cas14a1) system. Provided are an engineered guide RNA for more effectively performing cleavage, editing, or modifying of a target nucleic acid, and an engineered CRISPR/Cas12f1 (Cas14a1) system containing the engineered guide RNA. In addition, provided is a method of performing cleavage, editing, or modifying of a target nucleic acid by using the engineered guide RNA and the engineered CRISPR/Cas12f1 (Cas14a1) system including the engineered guide RNA.
    Type: Application
    Filed: October 8, 2021
    Publication date: December 28, 2023
    Applicant: GENKORE INC.
    Inventors: Yong-Sam KIM, Do Yon KIM, Jeong Mi LEE, Su Bin MOON
  • Composition for genome editing using CRISPR/CPF1 system and use thereof
    Patent number: 11667917
    Abstract: The present invention relates to a composition for genome editing using a CRISPR/Cpf1 system and a use thereof and, more particularly, to a composition for genome editing comprising: a CRISPR RNA (crRNA) including a guide sequence capable of hybridizing with a target nucleotide sequence, and a uridine repeat sequence connected to the 3?-end of the guide sequence, or a DNA encoding the same; and a Cpf1 protein or a DNA encoding the same, a method for genome editing using the same, a method for construction of a genetically modified organism, and a genetically modified organism. The present invention can increase an indel efficiency and decrease off-target activity in genome editing of eukaryotic cells using the CRIPSPR/Cpf1 system and thus can easily construct a genetically modified cell or genetically modified animal or plant having a desired gene inserted thereinto (knock-in) or deleted therefrom (knock-out).
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: June 6, 2023
    Assignee: GENKORE CO. LTD.
    Inventors: Yong Sam Kim, Jeong Heon Ko, Jeong Mi Lee, Su Bin Moon
  • COMPOSITION FOR GENOME EDITING USING CRISPR/CPF1 SYSTEM AND USE THEREOF
    Publication number: 20200308583
    Abstract: The present invention relates to a composition for genome editing using a CRISPR/Cpf1 system and a use thereof and, more particularly, to a composition for genome editing comprising: a CRISPR RNA (crRNA) including a guide sequence capable of hybridizing with a target nucleotide sequence, and a uridine repeat sequence connected to the 3?-end of the guide sequence, or a DNA encoding the same; and a Cpf1 protein or a DNA encoding the same, a method for genome editing using the same, a method for construction of a genetically modified organism, and a genetically modified organism. The present invention can increase an indel efficiency and decrease off-target activity in genome editing of eukaryotic cells using the CRIPSPR/Cpf1 system and thus can easily construct a genetically modified cell or genetically modified animal or plant having a desired gene inserted thereinto (knock-in) or deleted therefrom (knock-out).
    Type: Application
    Filed: November 21, 2018
    Publication date: October 1, 2020
    Inventors: Yong Sam KIM, Jeong Heon KO, Jeong Mi LEE, Su Bin MOON