Patents by Inventor Su Cheong Yeom

Su Cheong Yeom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic pig which simultaneously expresses HO-1 gene and TNFR1-Fc gene, and comprises knocked-out GGTA1 gene, and use thereof
    Patent number: 10717991
    Abstract: The present invention relates to a transgenic pig in which an immune rejection response is suppressed during xenotransplantation, wherein a gene coding for heme oxygenase-1 (HO-1) and a gene coding for tumor necrosis factor receptor 1-Fc (TNFR1-Fc) are simultaneously expressed and a gene coding for ?-1,3-galactosyltransferase (GGTA1) is knocked out; and a method for producing the same.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: July 21, 2020
    Assignees: CHONG KUN DANG PHARMACEUTICAL CORP., SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Byeong Chun Lee, Curie Ahn, Geon A Kim, Su Cheong Yeom, Su Jin Kim, Bumrae Cho, Eun Mi Lee, Sang Hoon Lee, In Chang Hwang, Hye Jin Hong
  • TRANSGENIC PIG WHICH SIMULTANEOUSLY EXPRESSES HO-1 GENE AND TNFR1-FC GENE, AND COMPRISES KNOCKED-OUT GGTA1 GENE, AND USE THEREOF
    Publication number: 20190024115
    Abstract: The present invention relates to a transgenic pig in which an immune rejection response is suppressed during xenotransplantation, wherein a gene coding for heme oxygenase-1 (HO-1) and a gene coding for tumor necrosis factor receptor 1-Fc (TNFR1-Fc) are simultaneously expressed and a gene coding for ?-1,3-galactosyltransferase (GGTA1) is knocked out; and a method for producing the same. The transgenic pig of the present invention, in which the genes coding for human HO-1 and TNFR1-Fc fusion protein are simultaneously expressed and the gene coding for GGTA1 is knocked out, may reduce oxidative stress during organ isolation and in vitro culture by antioxidative reaction, cytoprotective function, etc., and may also reduce a TNF-?-mediated inflammatory response in early transplantation by TNFR1-Fc expression.
    Type: Application
    Filed: November 11, 2016
    Publication date: January 24, 2019
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, CHONG KUN DANG PHARMACEUTICAL CORP.
    Inventors: Byeong Chun Lee, Cu Rie Ahn, Geon A Kim, Su Cheong Yeom, Su Jin Kim, Bum Rae Cho, Eun Mi Lee, Sang Hoon Lee, In Chang Hwang, Hye Jin Hong