Patents by Inventor Su CHONG

Su CHONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANNABINOID TYPE 1 RECEPTOR BINDING PROTEINS AND USES THEREOF
    Publication number: 20250277029
    Abstract: Described herein are anti-CB1 (e.g., huCB1) antibodies and antigen binding fragments, compositions comprising the same and their use for the treatment of various disorders or diseases such as obesity and its comorbidities, chronic kidney disease, liver disease (e.g., NAFLD), and NASH.
    Type: Application
    Filed: July 26, 2023
    Publication date: September 4, 2025
    Applicant: AMGEN INC.
    Inventors: Irwin CHEN, Su CHONG, Seog Joon HAN, Kirill OXENOID, Weihsu Claire CHEN, Venkata Nihal PASUMARTHI, John Bergen, Wadim Matochko, Dawn Weishuhn, Serina LI, Murielle Marie VENIANT-ELLISON, Elizabeth KILLION, Shu-Chen LU
  • PAC1 ANTIBODIES AND USES THEREOF
    Publication number: 20240150448
    Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.
    Type: Application
    Filed: December 19, 2023
    Publication date: May 9, 2024
    Applicant: AMGEN INC.
    Inventors: Neeraj Jagdish AGRAWAL, Irwin CHEN, Su CHONG, Bryna FUCHSLOCHER, Kevin GRAHAM, Agnes Eva HAMBURGER, Mark Leo MICHAELS, Christopher MOHR, Derek E. PIPER, Kenneth William WALKER, Zhulun WANG, Cen XU
  • Peptide PAC1 antagonists
    Patent number: 11643440
    Abstract: Novel peptides that bind to human PAC1 are provided. These peptides that are antagonists of PAC1 are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine, such as acute migraine.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: May 9, 2023
    Assignee: AMGEN INC.
    Inventors: Irwin Chen, Su Chong, Essa Hu Harrington, Fang-Tsao Hong, Jason C. Long, Leslie P. Miranda
  • ANTI-CGRP RECEPTOR/ANTI-PAC1 RECEPTOR BISPECIFIC ANTIGEN BINDING PROTEINS
    Publication number: 20220363770
    Abstract: The present invention relates to antagonist antibodies of the human calcitonin gene-related peptide (CGRP) receptor as well as bispecific antigen binding proteins derived from the anti-CGRP antibodies that bind to and inhibit both the human CGRP receptor and another target, such as the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) receptor. Pharmaceutical compositions comprising the anti-CGRP receptor antibodies and bispecific antigen binding proteins as well as methods for producing them are also disclosed. Methods of using the anti-CGRP receptor antibodies and bispecific antigen binding proteins to ameliorate, treat, or prevent conditions associated with the CGRP and PAC1 receptors, such as chronic pain, migraine, and cluster headache, are also described.
    Type: Application
    Filed: June 26, 2020
    Publication date: November 17, 2022
    Applicant: AMGEN INC.
    Inventors: Irwin CHEN, Su CHONG, Fernando GARCES, Mark Leo MICHAELS, Christopher MOHR, Kenneth William WALKER, Zhulun WANG, Neeraj Jagdish AGRAWAL, Bryna FUCHSLOCHER, Kevin GRAHAM, Agnes Eva HAMBURGER, Derek E. PIPER, Cen XU
  • PAC1 ANTIBODIES AND USES THEREOF
    Publication number: 20220195022
    Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.
    Type: Application
    Filed: December 21, 2021
    Publication date: June 23, 2022
    Applicant: AMGEN INC.
    Inventors: Neeraj Jagdish AGRAWAL, Irwin CHEN, Su CHONG, Bryna FUCHSLOCHER, Kevin GRAHAM, Agnes Eva HAMBURGER, Mark Leo MICHAELS, Christopher MOHR, Derek E. PIPER, Kenneth William WALKER, Zhulun WANG, Cen XU
  • PEPTIDE PAC1 ANTAGONISTS
    Publication number: 20210395313
    Abstract: Novel peptides that bind to human PAC1 are provided. These peptides that are antagonists of PAC1 are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine, such as acute migraine.
    Type: Application
    Filed: June 1, 2018
    Publication date: December 23, 2021
    Inventors: Irwin CHEN, Su CHONG, Essa Hu HARRINGTON, Fang-Tsao HONG, Jason C. LONG, Leslie P. MIRANDA
  • PAC1 ANTIBODIES AND USES THEREOF
    Publication number: 20210017261
    Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.
    Type: Application
    Filed: July 1, 2020
    Publication date: January 21, 2021
    Applicant: AMGEN INC.
    Inventors: Neeraj Jagdish AGRAWAL, Irwin CHEN, Su CHONG, Bryna FUCHSLOCHER, Kevin GRAHAM, Agnes Eva HAMBURGER, Mark Leo MICHAELS, Christopher MOHR, Derek E. PIPER, Kenneth William WALKER, Zhulun WANG, Cen XU
  • PAC1 ANTIBODIES AND USES THEREOF
    Publication number: 20190218279
    Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.
    Type: Application
    Filed: January 11, 2019
    Publication date: July 18, 2019
    Applicant: AMGEN INC.
    Inventors: Neeraj Jagdish AGRAWAL, Irwin CHEN, Su CHONG, Bryna FUCHSLOCHER, Kevin GRAHAM, Agnes Eva HAMBURGER, Mark Leo MICHAELS, Christopher MOHR, Derek E. PIPER, Kenneth William WALKER, Zhulun WANG, Cen XU