Abstract: Described herein is a novel, mitochondrial encoded, open reading frame that leads to the production of a new mitochondrial peptide called SHMOOSE. SHMOOSE is a 58-amino-acid peptide and, within its open reading frame, contains a genome-wide significant small nucleotide polymorphism (SNP) that markedly increased risk for Alzheimer's disease, brain structure, brain gene expression, and cognition. SHMOOSE increased neuronal-type cell survival and protected against amyloid beta toxicity. Metabolomic studies revealed a role for the peptide in energy optimization, whose dysfunction and dysregulation leads to cell death in physiologically notable regions of the brain in neurodegenerative diseases such as Alzheimer's and Parkinson's. Methods and compositions, including peptide analogues and derivatives, are described for treatment and diagnostics.

Abstract: Provided are a piperidine derivative compound, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for the prevention or treatment of diseases related to autotaxin activity, comprising same as an active ingredient, in which the piperidine derivative compound exhibits excellent inhibitory activity against autotaxin, and thus can be effectively used in the treatment and prevention of diseases related to autotaxin inhibition, such as fibrotic diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, metabolic diseases, cancer and cancer metastasis, ocular diseases, cholestatic form and other forms of chronic pruritus, and acute or chronic organ transplant rejection.

Abstract: A display device includes first to third light emitting units disposed on a substrate, an encapsulation layer disposed on the first to third light emitting units, a sensor electrode disposed on the encapsulation layer, an insulating layer disposed on the sensor electrode, first to third color filters disposed on the touch insulating layer and overlapping the first to third light emitting units in a thickness direction of the substrate, respectively. The sensor electrode overlaps at least one of the first color filter, the second color filter, and the third color filter in the thickness direction of the substrate.

Abstract: A display device including: a substrate; a plurality of light-emitting elements on the substrate; and a touch sensing layer disposed on the plurality of light-emitting elements, wherein the touch sensing layer includes: a first touch conductive layer; a first insulating layer disposed on the first touch conductive layer; and a second touch conductive layer disposed on the first insulating layer, and wherein the first insulating layer includes a light-converting material that converts light into near-infrared light.

Abstract: A display device includes a substrate, a plurality of pixel electrodes on the substrate and spaced apart from each other, a plurality of light-emitting elements on the plurality of pixel electrodes, respectively, and a common electrode layer on the plurality of light-emitting elements and to which a common voltage is applied. The plurality of light-emitting elements include a first light-emitting element that is configured to emit first light according to a first driving current and a second light-emitting element that is configured to emit second light according to a second driving current. An active layer of the first light-emitting element is the same as an active layer of the second light-emitting element.

Abstract: A display device includes a substrate, a plurality of pixels, and an encapsulation layer. The encapsulation layer is disposed on the pixels. The encapsulation layer has a multi-layer structure or a single-layer structure. When a distance (d) between the pixels and a thickness (t) of the encapsulation layer satisfies Mathematical Formula 1: t? (d/tan 10°), color mixing is prevented in the display device.

Abstract: The present invention provides antisense oligonucleotides for the treatment of various T-type calcium channel ?1G subunit-related disorders, and more specifically, antisense oligonucleotides for inhibiting expression of the gene encoding Cav3.1, targeting SEQ ID NO: 1, for the treatment of various neuropsychiatric disorders, including Parkinson's disease, epilepsy, essential tremor, depression, anxiety disorders, and unconsciousness.

Abstract: The present invention relates to a method for preparing a conjugated diene-based polymer, which includes a step of preparing a conjugated diene-based polymer by initiating and carrying out polymerization while continuously adding conjugated diene-based monomers to a reactor, and in which an emulsifier is dividedly added before the initiation of the polymerization and when a polymerization conversion rate of 31% to 80% is reached. More particularly, the present invention relates to: a method for preparing a conjugated diene-based polymer and a method for preparing a graft copolymer including the method for preparing a conjugated diene-based polymer, by which a total usage amount of an emulsifier can be reduced.

Abstract: A display module includes a display panel including a silicon substrate including pixel areas, a driving circuit layer disposed on the silicon substrate, a light emitting layer disposed on the driving circuit layer and extending over the pixel areas continuously, and a color filter disposed in the pixel areas on the light emitting layer, a phase retardation plate disposed on the display panel, and a wire grid polarizer disposed on the phase retardation plate and including metal patterns spaced apart from each other at selectable intervals.

Abstract: A display device comprises a substrate, an organic light emitting element layer comprising a first electrode, a second electrode, and an organic light emitting layer disposed between the first and second electrodes and emitting light in a light emitting area, an encapsulation layer covering the organic light emitting element layer, a color filter layer disposed in the light emitting area and including a plurality of color filters having different colors and a light control pattern layer disposed between the encapsulation layer and the color filter layer and including a light control pattern disposed on a light path of the organic light emitting layer.

Abstract: The present invention relates to an agent for improving aftertaste of alcoholic beverages comprising allulose-containing saccharides, and a method for improving aftertaste of alcoholic beverages using allulose.

Abstract: A light emitting display device according to an embodiment includes a driving element layer disposed on a substrate, a light emitting element layer disposed on the driving element layer, and an external light decreasing layer disposed on the light emitting element layer. The light emitting element layer includes an anode, a pixel defining film having a first opening exposing at least a portion of the anode, a light emitting layer disposed on the anode in the first opening of the pixel defining film, and a cathode disposed on the light emitting layer and the pixel defining film. The external light decreasing layer includes an inorganic material having an absorption coefficient of greater than or equal to about 1.5, and includes a reflection control layer having a second opening corresponding to the first opening of the pixel defining film.

Abstract: A display device includes a light emitting area and a light blocking area, a light emitting device layer including first through third light emitting devices corresponding to the light emitting area, a light blocking layer including a light blocking member which is in the light blocking area and defines a first opening overlapping the first light emitting device, a second opening overlapping the second light emitting device, and a third opening overlapping the third light emitting device, a color filter layer including a first color filter in the first opening and a second color filter in the second opening, and an anti-reflection layer on the light blocking layer and the color filter layer, the anti-reflection layer including a pigment or a dye. The light blocking layer together with the color filter layer and the anti-reflection layer defines a polarizer of the display device.

Abstract: A display device includes: a base layer; and light emitting elements disposed on the base layer, the light emitting elements including an N-type semiconductor layer, a P-type semiconductor layer, and an active layer disposed between the N-type and P-type semiconductor layers. The light emitting elements include a first light emitting element emitting light of a first color and a second light emitting element emitting light of a second color. The N-type semiconductor layer includes a first N-type semiconductor layer of the first light emitting element and a second N-type semiconductor layer of the second light emitting element. The active layer includes a first active layer of the first light emitting element and a second active layer of the second light emitting element. The first and second N-type semiconductor layers are integral with each other, and form a plane surface in an area where the active layer is disposed.

Abstract: A pixel includes first, second, and third sub-pixels each including an emission area and a non-emission area. Each of the first, second, and third sub-includes a pixel circuit layer; a first electrode on the pixel circuit layer; a pixel defining layer on the first electrode and including an opening to expose an area of the first electrode; an emission layer on the pixel defining layer; a second electrode on the emission layer; a thin film encapsulation layer over the second electrode; a color filter on the thin film encapsulation layer; and an overcoat layer over the color filter. The overcoat layer has a refractive index greater than a refractive index of the color filter. A color filter of the second sub-pixel overlaps a color filter of each of the first and third sub-pixels in the non-emission area.

Abstract: A display device includes a display panel, a filler layer, a reflection control layer, a plurality of light-blocking patterns, and an encapsulation substrate. The low reflection layer is disposed on the display panel. The filler layer is disposed on the display panel. The reflection control layer includes a first catalyst and is disposed on the filler layer. The plurality of light-blocking patterns is disposed between the filler layer and the reflection control layer. The encapsulation substrate is disposed on the reflection control layer.

Abstract: A display device includes a substrate, conductive pads arranged on the substrate over a plurality of rows, and a drive circuit chip including bumps arranged over a plurality of rows to be electrically connected with the conductive pads, and the conductive pads arranged in a same row are arranged in parallel, and the bumps arranged in a same row are arranged in a zigzag form so as to be partially shifted.

Abstract: The present invention relates to a compound capable of lowering the flammability of a non-aqueous electrolyte when included in the non-aqueous electrolyte and improving the life properties of a battery by forming an electrode-electrolyte interface which is stable at high temperatures and low in resistance, and relates to a compound represented by Formula I descried herein, a non-aqueous electrolyte solution and a lithium secondary battery both including the compound, n, m, Ak, and X are described herein.

Abstract: A display device includes a substrate, a plurality of pixel electrodes on the substrate and spaced apart from each other, a plurality of light-emitting elements on the plurality of pixel electrodes, respectively, and a common electrode layer on the plurality of light-emitting elements and to which a common voltage is applied. The plurality of light-emitting elements include a first light-emitting element that is configured to emit first light according to a first driving current and a second light-emitting element that is configured to emit second light according to a second driving current. An active layer of the first light-emitting element is the same as an active layer of the second light-emitting element.

Abstract: A display device includes a substrate including a pixel circuit unit, a partition wall including a distributed Bragg reflector (DBR) structure partitioning a light-emitting area and a non-light-emitting area, and light-emitting elements above the substrate, corresponding to the light-emitting area, and including a first semiconductor layer, an active layer, and a porous semiconductor layer.