Abstract: Compositions and methods for treating Duchenne Muscular Dystrophy (DMD) and excising small portions of exons 44, 50, and 53 of the DMD gene are encompassed.

Abstract: The present disclosure relates in some aspects to methods, systems, and kits for analyzing a biological sample comprising generating a rolling circle amplification product (RCP) using a target ribonucleic acid (RNA) as a primer. In some aspects, RNase H and a nucleic acid oligonucleotide are used to generate a free 3? end of the target RNA to prime RCA.

Abstract: Disclosed in the present invention are a bottom anti-reflective coating for deep ultraviolet lithography, a preparation method therefor and the use thereof. A polymer disclosed in the present invention is prepared by the following method: (1) preheating a solvent I; (2) mixing a monomer as shown in formula (A), a monomer as shown in formula (B), a monomer as shown in formula (C), a cross-linking agent as shown in formula (L), and an initiator and a solvent II to obtain a mixed solution; and (3) adding the mixed solution to a preheated solvent and perform a polymerization reaction, wherein step (1) and step (2) are in no particular order. The bottom anti-reflective coating for deep ultraviolet lithography can reduce the reflectivity, and after the bottom anti-reflective coating is spin-coated with a photoresist, no scum formed by the bottom anti-reflective coating is observed.

Abstract: The present disclosure relates to a preparation of CD140a/PDGFR? positive cells that comprises oligodendrocyte progenitor cells co-expressing OLIG2 and CD140a/PDGFR?. The preparation of cells is derived from pluripotent cells that were derived from skin cells, fibroblasts, umbilical cord blood, peripheral blood, bone marrow, or other somatic cells. The cell preparation has an in vivo myelination efficiency that is equal to or greater than the in vivo myelination efficiency of a preparation of A2B5+/PSA-NCAM? sorted fetal human tissue derived oligodendrocyte progenitor cells. Methods of making, isolating and using the disclosed cell preparation are also described.

Abstract: An additive for 193 nm dry photoresist and a preparation method for and application of the additive. The structure of the additive is as shown in formula I, the weight-average molecular weight is 1000-3000, and the ratio of the weight-average molecular weight to the number-average molecular weight is 1-5. By using the additive, photoresist can form a photoresist film micropattern having excellent sensitivity and high resolution.

Abstract: Compositions and methods for treating Duchenne Muscular Dystrophy (DMD) and excising small portions of exons of the DMD gene are encompassed.

Abstract: The present disclosure relates to a preparation of CD140a/PDGFR? positive cells that comprises oligodendrocyte progenitor cells co-expressing OLIG2 and CD140a/PDGFR?. The preparation of cells is derived from pluripotent cells that were derived from skin cells, fibroblasts, umbilical cord blood, peripheral blood, bone marrow, or other somatic cells. The cell preparation has an in vivo myelination efficiency that is equal to or greater than the in vivo myelination efficiency of a preparation of A2B5+/PSA-NCAM? sorted fetal human tissue derived oligodendrocyte progenitor cells. Methods of making, isolating and using the disclosed cell preparation are also described.

Abstract: Disclosed in the present invention are a polyonium salt photoacid generator for ArF light source dry lithography, and a preparation method therefor and an application thereof. The photoacid generator is an onium salt having an anions and an onium ion, the anion having a structure as shown in formula (I), the onium ion having a structure shown in formula (A) or formula (B), and the number of onium ions keeping the charge of the onium salt neutral. A photoresist comprising the onium salt of the present invention has better resolution, sensitivity and linewidth roughness.

Abstract: Disclosed is a preparation method for triphenylchloromethane, comprising the following steps: adding hydrochloric acid or a mixture of hydrochloric acid and Lewis acid to a mixture of triphenylmethanol and an organic solvent; stirring for reaction; removing the water layer after the completion of reaction to obtain an organic solution containing triphenylchloromethane. In the method, the conversion rate of triphenylmethanol is almost quantitative to be above 99%, and the content of triphenylchloromethane in the product obtained is above 99%. The operation is simple, and no waste gas is generated. Therefore, the method is environmentally friendly and suitable for industrialized production and can achieve better economic benefits.

Abstract: A resin, and an ArF dry photoresist composition comprising same and an application. The resin is obtained by polymerizing the following monomers in parts by weight: 40-47.5 parts of a monomer (A), 0.5-5 parts of a monomer (B), 0.25-2.5 parts of a monomer (C), and 0.25-2.5 parts of a monomer (D). A photoresist comprising the resin has the advantages of being high in resolution, high in sensitivity, and low in line width roughness.

Abstract: Some embodiments provide a centralized overlay-network cloud gateway and a set of centralized services in a transit virtual cloud network (VCN) connected to multiple other compute VCNs hosting compute nodes (VMs, containers, etc.) that are part of (belong to) the overlay network. The centralized overlay-network cloud gateway provides connectivity between compute nodes of the overlay network (e.g., a logical network spanning multiple VCNs) and compute nodes in external networks. Some embodiments use the centralized overlay-network cloud gateway to provide transitive routing (e.g., routing through a transit VCN) in the absence of direct peering between source and destination VCNs. The overlay network, of some embodiments, uses the same subnetting and default gateway address for each compute node as the cloud provider network provided by the virtual private cloud provider.

Abstract: An adaptive approach to image bracket determination and a more memory-efficient approach to image fusion, which are designed to generate low noise and high dynamic range (HDR) images in a wide variety of capturing conditions, are described. An incoming preview image stream may be obtained from an image capture device. When a capture request is received, an analysis may be performed on an image from the preview image stream that has a predetermined temporal relationship to the image capture request. Based on the analysis, a set of images (and their respective capture parameters, e.g., exposure time) may be determined for the image capture device to capture. As the determined set of images are captured, they may be registered and fused in a memory-efficient manner that, e.g., places an upper limit on the overall memory footprint of the registration and fusion operations—regardless of how many images are captured in total.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that validate the performance of a dispatch model, such as a directive-based model, utilized for facilitating transportation matching services. For example, the disclosed systems can generate critical situations clusters composed of groups of critical transportation provider performance scenarios. From the critical situation clusters, the disclosed systems can sample one or more critical transportation provider situations that present a risk of degradation for the transportation matching services. Accordingly, the disclosed systems can measure a performance of the dispatch model by employing a simulation model that utilizes the dispatch model to propagate the critical transportation provider situations through time.

Abstract: Provided are a resin and a 193 nm dry photoresist containing same, and a preparation method therefor and the use thereof. The resin is a copolymer obtained by polymerizing a monomer represented by formula (A), a monomer represented by formula (B), a monomer represented by formula (C), and a monomer represented by formula (D), wherein the resin comprises 42.5-49.5 parts by weight of the monomer represented by formula (A), 1-7.5 parts by weight of the monomer represented by formula (B), 0.25-2.5 parts by weight of the monomer represented by formula (C), and 0.25-2.5 parts by weight of the monomer represented by formula (D). The photoresist containing the resin at least has the following advantages: excellent photosensitivity, a good depth of focus, and a good line width uniformity.

Abstract: A multi-channel payment method for a multi-channel payment system comprises the payer or the payee who initiated the payment request logs in to the multi-channel payment system; the payer or the payee who initiated the payment request placing an order in the multi-channel payment system, wherein the order comprises a designated payment gateway; the multi-channel payment system determining a predicted fee of the order according to the designated payment gateway, past order records, and a real-time exchange rate; the multi-channel payment system performing an anti-money laundering verification of the order; the payer reviewing the order and the predicted fee through a multiple auditing method; and the multi-channel payment system executing payment from the payer to the payee according to the order and the designated payment gateway, and storing a payment detail of the order.

Abstract: A method for model training, an image edge detection method, a multi-sensor calibration method, a computer program product, and a computer device is disclosed. The model is used to generate occlusion relationships between pixel pairs. The model training method comprises: constructing an initial model; obtaining multiple training images and reference annotation results for each training image, wherein each training image comprises RGB features and depth features, and the reference annotation results for each training image are annotation results of occlusion relationships between adjacent pixel pairs in said training image generated based on the depth features of said training image; respectively using the RGB features of the multiple training images as inputs to the initial model, using the reference annotation results corresponding to the input training images as outputs of the initial model, and training the initial model to obtain a well-trained model.

Abstract: This application relates to clock synchronization methods optical head ends, and optical terminals. In an example method, the optical head end receives a first packet from a controller. The first packet includes service data to be transmitted to a plurality of slave stations. The optical head end generates a second packet based on the first packet. The second packet includes the service data and time information. The time information indicates an execution time point at which the plurality of slave stations perform an operation based on the service data. The optical head end further sends the second packet to the plurality of optical terminals to request the plurality of optical terminals to control the plurality of slave stations to perform the operation at the execution time point based on the service data.

Abstract: Some embodiments provide a method for a first data compute node (DCN) operating in a public datacenter. The method receives an encryption rule from a centralized network controller. The method determines that the network encryption rule requires encryption of packets between second and third DCNs operating in the public datacenter. The method requests a first key from a secure key storage. Upon receipt of the first key, the method uses the first key and additional parameters to generate second and third keys. The method distributes the second key to the second DCN and the third key to the third DCN in the public datacenter.

Abstract: Embodiments of this application disclose an optical bus communication method, including: A first terminal obtains first control information from a controller, where the first control information is generated by the controller and is used to control an execution mechanism to work. The first terminal sends the first control information to a central office over a first section, so that the central office forwards the first control information to a second terminal, where the second terminal is connected to the execution mechanism. The first terminal obtains first state information from the central office, where the first state information is used to record a working state of the execution mechanism, the first state information is information sent by the second terminal to the central office over a second section after the second terminal obtains the first control information, and the first section does not overlap with the second section.

Abstract: Some embodiments provide a method for a first data compute node (DCN) operating in a public datacenter. The method receives an encryption rule from a centralized network controller. The method determines that the network encryption rule requires encryption of packets between second and third DCNs operating in the public datacenter. The method requests a first key from a secure key storage. Upon receipt of the first key, the method uses the first key and additional parameters to generate second and third keys. The method distributes the second key to the second DCN and the third key to the third DCN in the public datacenter.