Patents by Inventor Su-Yang Liu

Su-Yang Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Broad antiviral therapy with membrane modifying oxysterols
    Patent number: 11020409
    Abstract: This invention relates, e.g., to a method for inhibiting the growth and/or proliferation and/or infectivity of a virus in a cell, such as a mammalian cell (e.g. for inhibiting entry of the virus into the cell), comprising administering, or causing to be administered, to the cell, 25-hydroxycholesterol (25HC) in an amount sufficient to inhibit the growth and/or proliferation and/or infectivity of the vines in the cell. The method can be carried out in vivo or in vitro. Among the viruses that can be inhibited are, e.g., VSV, HSV, MHV68, HCV, HIV, EBOV, RVFV, RSSEV and Nipah virus. In one embodiment of the invention, the 25HC is administered topically, e.g. to a mucosal surface.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: June 1, 2021
    Assignee: The Regents of the University of California
    Inventors: Genhong Cheng, Su-Yang Liu
  • BROAD ANTIVIRAL THERAPY WITH MEMBRANE MODIFYING OXYSTEROLS
    Publication number: 20190015426
    Abstract: This invention relates, e.g., to a method for inhibiting the growth and/or proliferation and/or infectivity of a virus in a cell, such as a mammalian cell (e.g. for inhibiting entry of the virus into the cell), comprising administering, or causing to be administered, to the cell, 25-hydroxycholesterol (25HC) in an amount sufficient to inhibit the growth and/or proliferation and/or infectivity of the vines in the cell. The method can be carried out in vivo or in vitro. Among the viruses that can be inhibited are, e.g., VSV, HSV, MHV68, HCV, HIV, EBOV, RVFV, RSSEV and Nipah virus. In one embodiment of the invention, the 25HC is administered topically, e.g. to a mucosal surface.
    Type: Application
    Filed: May 24, 2018
    Publication date: January 17, 2019
    Inventors: Genhong Cheng, Su-Yang Liu
  • BROAD ANTIVIRAL THERAPY WITH MEMBRANE MODIFYING OXYSTEROLS
    Publication number: 20150133420
    Abstract: This invention relates, e.g., to a method for inhibiting the growth and/or proliferation and/or infectivity of a virus in a cell, such as a mammalian cell (e.g. for inhibiting entry of the virus into the cell), comprising administering, or causing to be administered, to the cell, 25-hydroxycholesterol (25HC) in an amount sufficient to inhibit the growth and/or proliferation and/or infectivity of the virus in the cell. The method can be carried out in vivo or in vitro. Among the viruses that can be inhibited are, e.g., VSV, HSV, MHV68, HCV, HIV, EBOV, RVFV, RSSEV and Nipah virus. In one embodiment of the invention, the 25HC is administered topically, e.g. to a mucosal surface.
    Type: Application
    Filed: May 6, 2013
    Publication date: May 14, 2015
    Inventors: Genhong Cheng, Su-Yang Liu