Patents by Inventor Su-Yi HSU

Su-Yi HSU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KLK6-MEDIATED CNS-SPECIFIC ANTIBODY PRODRUG ACTIVATION
    Publication number: 20190203192
    Abstract: An antibody prodrug capable of being selectively activated in a central nervous system (CNS) by protease KLK6 includes an antibody for treating a disease or disorder in the CNS; a KLK6 cleavable peptide fused to an N-terminus of a heavy chain and/or a light chain of the antibody; and a blocker fused to an N-terminus of the KLK6 cleavable peptide. The disease or disorder is a cancer, inflammatory disease, autoimmune disease, infectious disease, or neuron degeneration disease.
    Type: Application
    Filed: December 30, 2017
    Publication date: July 4, 2019
    Applicant: Development Center for Biotechnology
    Inventors: Jei-Hwa YU, Iok-U FONG, Su-Yi HSU, Chih-Yung HU, Chia-Cheng WU