Patents by Inventor Subas M. Sakya

Subas M. Sakya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidone Compounds As GSK-3 Inhibitors
    Publication number: 20100292205
    Abstract: The invention pertains to pyrimidone compounds that serve as effective GSK-3 inhibitors. The invention further relates to pharmaceutical compositions and methods comprising such pyrimidone compounds; and the use of such compounds for treating certain disorders.
    Type: Application
    Filed: August 13, 2007
    Publication date: November 18, 2010
    Applicant: PFIZER INC.
    Inventors: Bruce A. Lefker, Michael A. Brodney, Subas M. Sakya, Bruce A. Hay, Matthew D. Wessel, Edward L. Conn
  • Cannabinoid receptor ligands and uses thereof
    Patent number: 7232823
    Abstract: Compounds of Formula (I) or (II) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein
    Type: Grant
    Filed: May 25, 2004
    Date of Patent: June 19, 2007
    Assignee: Pfizer, Inc.
    Inventors: Philip A. Carpino, Subas M. Sakya
  • Heterocyclo-alkylsulfonyl pyrazoles
    Patent number: 7056933
    Abstract: The present invention relates to heterocyclo alkylsulfonyl pyrazoles of the formula I: wherein the ring of the formula (R5)—A—(SOmR4), m, X, R1 through R5 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: June 6, 2006
    Assignee: Pfizer Inc.
    Inventors: Subas M. Sakya, Martha L. Minich
  • Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents
    Patent number: 6900230
    Abstract: The present invention relates to compounds of the formula wherein R1, R3, R5, R6, and A are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment of inflammation and other inflammation associated disorders, such as osteoarthritis, rheumatoid arthritis, colon cancer and Alzheimer's disease, in mammals (preferably humans, dogs, cats and livestock).
    Type: Grant
    Filed: July 2, 2002
    Date of Patent: May 31, 2005
    Assignee: Pfizer Inc.
    Inventors: Subas M. Sakya, Bryson Rast
  • 5-heteroatom-substituted pyrazoles
    Patent number: 6894067
    Abstract: The present invention relates to 5-heteroatom-substituted pyrazoles of the formula I: wherein the ring of the formula (R5)-A-(SOmR4), m, B, R1 through R5 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: May 17, 2005
    Assignee: Pfizer, Inc.
    Inventors: Martha L. Minich, Subas M. Sakya, Andrei Shavnya, Kristin Lundy DeMello
  • Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents
    Patent number: 6875779
    Abstract: The present invention relates to compounds of the formula wherein R1, R3, R5 and A are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment of inflammation and other inflammation associated disorders, such as osteoarthritis, rheumatoid arthritis, colon cancer and Alzheimer's disease, in mammals (preferably humans, dogs, cats and livestock).
    Type: Grant
    Filed: April 22, 2004
    Date of Patent: April 5, 2005
    Assignee: Pfizer Inc.
    Inventors: Subas M. Sakya, Andrei Shavnya, Bryson Rast
  • Hydrazinyl and nitrogen oxide pyrazoles
    Patent number: 6864252
    Abstract: The present invention relates to hydrazinyl and nitrogen oxide pyrazoles of the formula I: wherein the ring of the formula (R5)-A-(SOmR4), m, X, R1 through R5 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: March 8, 2005
    Assignee: Pfizer, Inc.
    Inventors: Subas M. Sakya, Bryson Rast
  • 5-(alkylidene-cycloalkyl)-and 5-(alkylidene-heterocyclyl)-pyrazoles
    Patent number: 6838458
    Abstract: The present invention relates to 5-(alkylidene-cycloalkyl)-pyrazoles and 5-(alkylidene-heterocyclyl)-pyrazoles of the formula I: wherein the ring of the formula (R5)-A-(SOmR4), m, B, ring G, R1 through R7 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: January 4, 2005
    Assignee: Pfizer, Inc.
    Inventor: Subas M. Sakya
  • Cannabinoid receptor ligands and uses thereof
    Publication number: 20040248881
    Abstract: Compounds of Formula (I) or (II) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.
    Type: Application
    Filed: May 25, 2004
    Publication date: December 9, 2004
    Applicant: Pfizer Inc
    Inventors: Philip A. Carpino, Subas M. Sakya
  • Cannabinoid receptor ligands and uses thereof
    Publication number: 20040235926
    Abstract: Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the modulation of the cannabinoid receptors in animals are described herein.
    Type: Application
    Filed: May 3, 2004
    Publication date: November 25, 2004
    Applicant: Pfizer Inc.
    Inventor: Subas M. Sakya
  • Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents
    Publication number: 20040198735
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: April 22, 2004
    Publication date: October 7, 2004
    Inventors: Subas M. Sakya, Andrei Shavnya, Bryson Rast
  • Sulfonyl heteroaryl triazoles as anti-inflammatory/analgesic agents
    Patent number: 6753332
    Abstract: The present invention relates to compounds of the formula wherein R1, R3, R5 and A are defined as in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment of inflammation and other inflammation associated disorders, such as osteoarthritis, rheumatoid arthritis, colon cancer and Alzheimer's disease, in mammals (preferably humans, dogs, cats and livestock).
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: June 22, 2004
    Assignee: Pfizer, Inc.
    Inventors: Subas M. Sakya, Andrei Shavnya, Bryson Rast
  • Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents
    Publication number: 20030236258
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: January 14, 2003
    Publication date: December 25, 2003
    Applicant: Pfizer Inc.
    Inventors: Kristin M. Lundy, Hengmiao Cheng, Subas M. Sakya, Jin Li, Martha L. Minich, Chikara Uchida
  • Heteroaryl phenyl pyrazole compounds as anti-inflammatory/analgesic agents
    Patent number: 6649636
    Abstract: This invention relates to a compound of the formula: or a pharmaceutically acceptable salt thereof, wherein A and R1 are each an optionally substituted 5 to 6-membered heteroaryl, wherein the heteroaryl is optionally fused to a carbocyclic ring or 5 to 6-heteroaryl; R2 is (C1-C4)alkyl optionally substituted with halo, amino or an alkyl amino; R3 and R4 are each hydrogen, halo, (C1-C4)alkyl optionally substituted with halo and the like; and X1 to X4 are each hydrogen, halo, hydroxy, (C1-C4)alkyl optionally substituted with halo and the like. These compounds have COX-2 inhibiting activity and thus useful for treating or preventing inflammation or other COX-2 related diseases.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: November 18, 2003
    Assignee: Pfizer Inc.
    Inventors: Kazuo Ando, Martha L. Minich, Jin Li, Subas M. Sakya, Kristin M. Lundy, Hengmiao Cheng, Brian S. Bronk, Kiyoshi Kawamura, Tomoki Kato
  • 5-heterocyclo-pyrazoles
    Patent number: 6627626
    Abstract: The present invention relates to 5-heterocyclo-pyrazoles of the formula I: wherein ring W, m, n, and R1 through R5 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: September 30, 2003
    Assignee: Pfizer Inc.
    Inventors: Martha L. Minich, Subas M. Sakya
  • 5-Heterocyclo-pyrazoles
    Publication number: 20030144279
    Abstract: The present invention relates to 5-heterocyclo-pyrazoles of the formula I: 1
    Type: Application
    Filed: November 1, 2002
    Publication date: July 31, 2003
    Inventors: Martha L. Minich, Subas M. Sakya
  • 5-(Alkylidene-cycloalkyl)-and 5-(alkylidene-heterocyclyl)-pyrazoles
    Publication number: 20030134839
    Abstract: The present invention relates to 5-(alkylidene-cycloalkyl)-pyrazoles and 5-(alkylidene-heterocyclyl)-pyrazoles of the formula I: 1
    Type: Application
    Filed: November 1, 2002
    Publication date: July 17, 2003
    Inventor: Subas M. Sakya
  • Hydrazinyl and nitrogen oxide pyrazoles
    Publication number: 20030134850
    Abstract: The present invention relates to hydrazinyl and nitrogen oxide pyrazoles of the formula I: 1
    Type: Application
    Filed: November 1, 2002
    Publication date: July 17, 2003
    Applicant: Pfizer Inc.
    Inventors: Subas M. Sakya, Bryson Rast
  • 5-Heteroatom-substituted pyrazoles
    Publication number: 20030134858
    Abstract: The present invention relates to 5-heteroatom-substituted pyrazoles of the formula I: 1
    Type: Application
    Filed: November 1, 2002
    Publication date: July 17, 2003
    Inventors: Martha L. Minich, Subas M. Sakya, Andrei Shavnya, Kristin Lundy DeMello
  • Sulfonyl aryl triazoles as anti-inflammatory/analgesic agents
    Publication number: 20030125368
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: July 2, 2002
    Publication date: July 3, 2003
    Inventors: Subas M. Sakya, Andrei Shavnya, Bryson Rast