Patents by Inventor Subham Ghosh

Subham Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220240828
    Abstract: Systems, interfaces, and methods are described herein for evaluation and adjustment cardiac therapy. The systems, interfaces, and methods may utilize, or include, a graphical user interface to display various information with respect to a plurality of external electrodes and electrical activity monitored using such external electrodes and to allow a user to adjust what information to display.
    Type: Application
    Filed: April 15, 2022
    Publication date: August 4, 2022
    Inventors: Subham Ghosh, Karen Kleckner, Melissa Rhodes, D'Anne Kudlik, Jordyn Reich, Keelia Doyle, Joshua Blauer
  • Patent number: 11400296
    Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: August 2, 2022
    Assignee: Medtronic, Inc.
    Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I. Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann, Jean Rutten
  • Publication number: 20220193421
    Abstract: In a medical device system, a computer apparatus is configured to receive body surface electrical signals from an electrode apparatus including multiple external electrodes. The computing apparatus generates electrical dyssynchrony data from the body surface electrical signals during delivery of His bundle pacing pulses and identifies effective His bundle capture based on the electrical dyssynchrony data. The computing apparatus generates an indication of His bundle capture in response to identifying the effective His bundle capture.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 23, 2022
    Inventor: Subham GHOSH
  • Publication number: 20220168576
    Abstract: Systems and methods are described herein related to the evaluation and adjustment of left bundle branch (LBB) pacing therapy. Evaluation of the LBB pacing therapy may utilize electrical activity monitored from a plurality of external electrodes. The electrical activity may be used to provided one or more metrics of dispersion of surrogate cardiac electrical activation times, which may then be used to evaluate, and potentially adjust the LBB pacing therapy.
    Type: Application
    Filed: November 8, 2021
    Publication date: June 2, 2022
    Inventor: Subham Ghosh
  • Publication number: 20220161035
    Abstract: An implantable device and associated method for delivering multi-site pacing therapy is disclosed. The device comprises a set of electrodes including a first and second left ventricular electrodes spatially separated from one another and a right ventricular electrode, all coupled to an implantable pulse generator. The processing circuit coupled to the implantable pulse generator, the processing circuit configured to determine whether a prospective heart failure condition has occurred and if so to trigger the pulse generator to switch from a first pacing mode to a second pacing mode, the first pacing mode comprising delivering only a first pacing pulse to a left ventricle (LV) and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle and the second pacing mode comprising delivering first and a second pacing pulses to the LV and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle.
    Type: Application
    Filed: February 11, 2022
    Publication date: May 26, 2022
    Inventors: Berthold Stegemann, Richard Cornelussen, Joeri Heynens, Subham Ghosh
  • Patent number: 11304641
    Abstract: Systems, interfaces, and methods are described herein for evaluation and adjustment cardiac therapy. The systems, interfaces, and methods may utilize, or include, a graphical user interface to display various information with respect to a plurality of external electrodes and electrical activity monitored using such external electrodes and to allow a user to adjust what information to display.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: April 19, 2022
    Assignee: Medtronic, Inc.
    Inventors: Subham Ghosh, Karen Kleckner, Melissa Rhodes, Jordyn Reich
  • Publication number: 20220111216
    Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 14, 2022
    Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I. Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann
  • Publication number: 20220111217
    Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 14, 2022
    Inventor: Subham Ghosh
  • Patent number: 11291845
    Abstract: In a medical device system, a computer apparatus is configured to receive body surface electrical signals from an electrode apparatus including multiple external electrodes. The computing apparatus generates electrical dyssynchrony data from the body surface electrical signals during delivery of His bundle pacing pulses and identifies effective His bundle capture based on the electrical dyssynchrony data. The computing apparatus generates an indication of His bundle capture in response to identifying the effective His bundle capture.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: April 5, 2022
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: 11285312
    Abstract: Systems and methods are described herein for evaluation and adjustment of a left ventricular assist device (LVAD). The systems and methods may utilize at least a plurality of external electrodes to monitor cardiac electrical activity before and during LVAD therapy. The cardiac electrical activity as well as other information such cardiac sound information may be used to determine and adjust one or more LVAD output parameters such as pump speed.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: March 29, 2022
    Assignee: Medtronic, Inc.
    Inventors: Jeffrey M. Gillberg, Subham Ghosh, Michael F. Hess, Troy E. Jackson
  • Publication number: 20220088390
    Abstract: An implantable medical device system is configured to generate signals representing activity of a heart of a patient; determine, based on the signals, an intrinsic delay of the heart of the patient; determine whether the intrinsic delay is indicative of a first-degree heart block being present in the heart of the patient; determine a patient-specific timing regime for conduction system pacing based on whether the intrinsic delay is indicative of the first-degree heart block being present in the heart of the patient; and administer cardiac pacing to a native conduction system of the heart of the patient based on the timing regime.
    Type: Application
    Filed: September 7, 2021
    Publication date: March 24, 2022
    Inventors: Robert W. Stadler, Subham Ghosh, Jian Cao, Andrea Grammatico, Sarah Meloni, Xiaohong Zhou
  • Patent number: 11278727
    Abstract: An implantable device and associated method for delivering multi-site pacing therapy is disclosed. The device comprises a set of electrodes including a first and second left ventricular electrodes spatially separated from one another and a right ventricular electrode, all coupled to an implantable pulse generator. The processing circuit coupled to the implantable pulse generator, the processing circuit configured to determine whether a prospective heart failure condition has occurred and if so to trigger the pulse generator to switch from a first pacing mode to a second pacing mode, the first pacing mode comprising delivering only a first pacing pulse to a left ventricle (LV) and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle and the second pacing mode comprising delivering first and a second pacing pulses to the LV and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: March 22, 2022
    Assignee: Medtronic, Inc.
    Inventors: Berthold Stegemann, Richard Cornelussen, Joeri Heynens, Subham Ghosh
  • Patent number: 11253178
    Abstract: Systems, methods, and interfaces are described herein for noninvasively determining an optimal coronary sinus branch to cannulate for a medical electrical lead. One exemplary method involves applying an electrode apparatus having a plurality of electrodes to a torso of a patient. One of a right ventricular (RV) lead is introduced to a right ventricle or a right atrial (RA) lead is introduced to a right atrium. Noninvasively ultrasonic energy is introduced to a target tissue selected from a set of target tissues. In response to delivering ultrasonic energy to the cardiac tissue, a processing unit receives a torso-surface potential signal from each of a plurality of electrodes distributed on a torso of a patient for the target tissue. Signals are sensed from one of the RA lead and the RV lead in response to delivering ultrasonic energy. For at least a subset of the plurality of electrodes, calculating, with the processing unit, a torso-surface activation time based on the signal sensed from the electrode.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: February 22, 2022
    Assignee: Medtronic, Inc.
    Inventors: Robert W. Stadler, Subham Ghosh
  • Publication number: 20220032069
    Abstract: An electrode apparatus includes a portable amplifier and a plurality of external electrodes to be disposed proximate a patient's skin. A portable computing apparatus is operably coupled to the electrode apparatus. The portable computing apparatus is configured to monitor electrical activity from tissue of a patient using the plurality of external electrodes to generate a plurality of electrical signals over time. The portable computing apparatus is configured to perform at least one of optimizing at least one parameter of the of the implantable pacing device based on the plurality of electrical signals and determining cardiac synchrony based on the plurality of electrical signals.
    Type: Application
    Filed: July 26, 2021
    Publication date: February 3, 2022
    Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg, Trent M. Fischer, Elizabeth A. Schotzko
  • Publication number: 20220032070
    Abstract: Systems, interfaces, and methods are described herein related to the evaluation of a patient's cardiac conduction system and evaluation of cardiac conduction system pacing therapy being delivered to the patient's cardiac conduction system. Evaluation of the patient's cardiac conduction system may utilize a plurality of breakthrough maps to determine where a cardiac conduction system block may be located. Evaluation of cardiac conduction system pacing therapy may utilize various electrical heterogeneity information monitored before and during delivery of cardiac conduction system pacing therapy.
    Type: Application
    Filed: June 29, 2021
    Publication date: February 3, 2022
    Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg
  • Publication number: 20220031221
    Abstract: Cardiac electrical activity is monitored from tissue of the patient using the plurality of external electrodes. One or more cardiac metrics of the patient are generated based on the monitored electrical activity. It is determined whether the patient is a candidate for a cardiac resynchronization therapy (CRT) device based on a first global dyssynchrony metric using the one or more cardiac metrics if the patient has a right bundle branch block. It is determined whether the patient is a candidate for a cardiac resynchronization therapy (CRT) device based on a second global dyssynchrony metric using the one or more cardiac metrics if the patient does not have a right bundle branch block.
    Type: Application
    Filed: July 6, 2021
    Publication date: February 3, 2022
    Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg
  • Publication number: 20220032062
    Abstract: The present disclosure relates generally to pacing of the cardiac conduction system of a patient, and more particularly, to providing adaptive cardiac conducting system pacing therapy and to determining selective or non-selective capture of the cardiac conduction system by cardiac conduction system pacing therapy. The adaptive cardiac conduction system pacing therapy may adjust AV delay and VV delay based on various signals and metrics and may switch between cardiac conduction system pacing therapy exclusively and cardiac conduction system pacing therapy in combination with traditional left ventricular pacing therapy.
    Type: Application
    Filed: June 28, 2021
    Publication date: February 3, 2022
    Inventor: Subham Ghosh
  • Patent number: 11235159
    Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: February 1, 2022
    Assignee: Medtronic, Inc.
    Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I. Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann, Jean Rutten
  • Patent number: 11235161
    Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: February 1, 2022
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: 11219769
    Abstract: Methods and systems of evaluating cardiac pacing in candidate patients for cardiac resynchronization therapy and cardiac resynchronization therapy patients are disclosed. The methods and systems disclosed allow treatments to be personalized to patients by measuring the extent of tissue capture from cardiac pacing under various therapy parameter conditions. Systems and methods of optimizing right ventricle only cardiac pacing are also disclosed.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: January 11, 2022
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh