Patents by Inventor Subham Ghosh

Subham Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11944461
    Abstract: Systems and methods are described herein for generating representative cardiac information. The representative cardiac information may be based on a plurality of electrode signals monitored, or measured, over a plurality of cardiac cycles or heart beats. The systems and methods may remove unqualified cardiac cycles, remove invalid electrode signals, remove inconsistent cardiac cycles, and removing uncorrelated cardiac cycles, and then generate representative cardiac information based on the remaining cardiac cycles and electrode signals.
    Type: Grant
    Filed: November 30, 2020
    Date of Patent: April 2, 2024
    Assignee: Medtronic, Inc.
    Inventors: Subham Ghosh, Karen J. Kleckner, Marc C. Steckler, Trent M. Fischer, Daniel S. Flo
  • Patent number: 11938325
    Abstract: The present disclosure pertains to cardiac pacing methods and systems, and, more particularly, to cardiac resynchronization therapy (CRT). In particular, the present disclosure pertains to determining whether a patient is experiencing atrial fibrillation (AF). If the patient is experiencing AF, the efficacy of CRT is determined. A signal is sensed in response to a ventricular pacing stimulus. Through signal processing, a number of features are parsed from the signal and a determination is made as to whether the ventricular pacing stimulus evoked a response from the ventricle.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: March 26, 2024
    Assignee: Medtronic, Inc.
    Inventors: Richard M. T. Lu, Subham Ghosh, Robert W. Stadler
  • Patent number: 11911168
    Abstract: Systems and methods are described herein for determining whether cardiac conduction system pacing therapy may be beneficial and/or determining how proximal or distal a cardiac conduction system block may be using external cardiac signals. To do so, one or more left-sided metrics of electrical heterogeneity information may be generated based on left-sided surrogate cardiac electrical measured using a plurality of left external electrodes.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: February 27, 2024
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: 11911622
    Abstract: An implantable medical device system is configured to generate signals representing activity of a heart of a patient; determine, based on the signals, an intrinsic delay of the heart of the patient; determine whether the intrinsic delay is indicative of a first-degree heart block being present in the heart of the patient; determine a patient-specific timing regime for conduction system pacing based on whether the intrinsic delay is indicative of the first-degree heart block being present in the heart of the patient; and administer cardiac pacing to a native conduction system of the heart of the patient based on the timing regime.
    Type: Grant
    Filed: September 7, 2021
    Date of Patent: February 27, 2024
    Assignee: Medtronic, Inc.
    Inventors: Robert W. Stadler, Subham Ghosh, Jian Cao, Andrea Grammatico, Sarah Meloni, Xiaohong Zhou
  • Publication number: 20240032844
    Abstract: Systems and methods of generating atrial electrical heterogeneity using electrical activity monitored using a plurality of external electrodes are described herein. The atrial electrical heterogeneity may include P-wave electrical heterogeneity. The atrial electrical heterogeneity generated from electrical activity monitored during atrial pacing therapy may be used to evaluate and adjust atrial pacing therapy. The atrial electrical heterogeneity generated from electrical activity monitored during intrinsic activation may be used to evaluate a patient's cardiac condition.
    Type: Application
    Filed: July 12, 2023
    Publication date: February 1, 2024
    Inventor: Subham Ghosh
  • Publication number: 20240024688
    Abstract: The present disclosure relates generally to pacing of the cardiac conduction system of a patient, and more particularly, to providing adaptive cardiac conducting system pacing therapy and to determining selective or non-selective capture of the cardiac conduction system by cardiac conduction system pacing therapy. The adaptive cardiac conduction system pacing therapy may adjust AV delay and VV delay based on various signals and metrics and may switch between cardiac conduction system pacing therapy exclusively and cardiac conduction system pacing therapy in combination with traditional left ventricular pacing therapy.
    Type: Application
    Filed: August 17, 2023
    Publication date: January 25, 2024
    Inventor: Subham Ghosh
  • Patent number: 11850431
    Abstract: An implantable device and associated method for delivering multi-site pacing therapy is disclosed. The device comprises a set of electrodes including a first and second left ventricular electrodes spatially separated from one another and a right ventricular electrode, all coupled to an implantable pulse generator. The processing circuit coupled to the implantable pulse generator, the processing circuit configured to determine whether a prospective heart failure condition has occurred and if so to trigger the pulse generator to switch from a first pacing mode to a second pacing mode, the first pacing mode comprising delivering only a first pacing pulse to a left ventricle (LV) and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle and the second pacing mode comprising delivering first and a second pacing pulses to the LV and thereafter delivering an RV pacing pulse to the right ventricular electrode within a single cardiac cycle.
    Type: Grant
    Filed: February 11, 2022
    Date of Patent: December 26, 2023
    Assignee: Medtronic, Inc.
    Inventors: Berthold Stegemann, Richard Cornelussen, Joeri Heynens, Subham Ghosh
  • Patent number: 11819699
    Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: November 21, 2023
    Assignee: Medtronic, Inc.
    Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann, Jean Rutten
  • Patent number: 11813464
    Abstract: Systems, interfaces, and methods are described herein related to the evaluation of a patient's cardiac conduction system and evaluation of cardiac conduction system pacing therapy being delivered to the patient's cardiac conduction system. Evaluation of the patient's cardiac conduction system may utilize a plurality of breakthrough maps to determine where a cardiac conduction system block may be located. Evaluation of cardiac conduction system pacing therapy may utilize various electrical heterogeneity information monitored before and during delivery of cardiac conduction system pacing therapy.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: November 14, 2023
    Assignee: Medtronic, Inc.
    Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg
  • Patent number: 11813462
    Abstract: Systems and methods may monitor electrical activity of a patient's heart using electrodes during delivery of cardiac conduction system pacing therapy, generate electrical heterogeneity information (EHI) based on the monitored electrical activity during delivery of cardiac conduction system pacing therapy, and determine whether the cardiac conduction system pacing therapy would benefit from supplemental cardiac pacing therapy based on the generated EHI.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: November 14, 2023
    Assignee: Medtronic, Inc.
    Inventors: Subham Ghosh, Richard Cornelussen
  • Patent number: 11801390
    Abstract: An implantable medical device system and method for delivering cardiac resynchronization therapy (CRT) pacing that includes determining capture associated with the delivered CRT pacing is ineffective in response to the delivered CRT pacing. A reason for capture being ineffective is determined and a safety margin is adjusted if the determined reason for capture being ineffective is loss of capture and a left ventricle (LV) pre-excitation is adjusted if the determined reason for capture being ineffective is delayed LV depolarization. Monitoring for a change in effective cardiac resynchronization therapy is used to confirm that the adjustment of the CRT pacing was effective in resolving the ineffective capture.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: October 31, 2023
    Assignee: Medtronic, Inc.
    Inventors: Robert W. Stadler, Ruth N. Klepfer, Subham Ghosh, Yanina Grinberg
  • Publication number: 20230293893
    Abstract: An implantable medical device includes a plurality of electrodes to detect electrical activity, a motion detector to detect mechanical activity, and a controller to determine at least one electromechanical interval based on at least one of electrical activity and mechanical activity. The activity detected may be in response to delivering a pacing pulse according to an atrioventricular (AV) pacing interval using the second electrode. The electromechanical interval may be used to adjust the AV pacing interval. The electromechanical interval may be used to determine whether cardiac therapy is acceptable or whether atrial or ventricular remodeling is successful.
    Type: Application
    Filed: May 24, 2023
    Publication date: September 21, 2023
    Inventor: Subham Ghosh
  • Patent number: 11752347
    Abstract: The present disclosure relates generally to pacing of the cardiac conduction system of a patient, and more particularly, to providing adaptive cardiac conducting system pacing therapy and to determining selective or non-selective capture of the cardiac conduction system by cardiac conduction system pacing therapy. The adaptive cardiac conduction system pacing therapy may adjust AV delay and VV delay based on various signals and metrics and may switch between cardiac conduction system pacing therapy exclusively and cardiac conduction system pacing therapy in combination with traditional left ventricular pacing therapy.
    Type: Grant
    Filed: June 28, 2021
    Date of Patent: September 12, 2023
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Publication number: 20230256253
    Abstract: An implantable medical system may provide atrioventricular synchronous pacing using the ventricular septal wall. The system may include a ventricular electrode coupled to an intracardiac housing or a first medical lead implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the left ventricle of the patient's heart and a right atrial electrode coupled to a leadlet or second medical lead to deliver cardiac therapy to or sense electrical activity of the right atrium of the patient's heart. A right ventricular electrode may be coupled to the intracardiac housing or the first medical lead and implantable in the ventricular septal wall of the patient's heart to deliver cardiac therapy to or sense electrical activity of the right ventricle of the patient's heart.
    Type: Application
    Filed: April 21, 2023
    Publication date: August 17, 2023
    Inventor: Subham Ghosh
  • Patent number: 11712188
    Abstract: Systems and methods may monitor electrical activity of a patient's heart using electrodes during delivery of cardiac therapy and determine a degree of posterior left bundle branch engagement based on the monitored electrical activity. The systems and methods may adjust the cardiac therapy based on the degree of posterior left bundle branch engagement.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: August 1, 2023
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: 11701517
    Abstract: An implantable medical device includes a plurality of electrodes to detect electrical activity, a motion detector to detect mechanical activity, and a controller to determine at least one electromechanical interval based on at least one of electrical activity and mechanical activity. The activity detected may be in response to delivering a pacing pulse according to an atrioventricular (AV) pacing interval using the second electrode. The electromechanical interval may be used to adjust the AV pacing interval. The electromechanical interval may be used to determine whether cardiac therapy is acceptable or whether atrial or ventricular remodeling is successful.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: July 18, 2023
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Patent number: 11697025
    Abstract: Systems, methods, and devices are described herein for determining cardiac conduction system capture of ventricle from atrium (VfA) therapy. VfA therapy may be delivered at a plurality of different A-V delays while electrical activity of the patient is monitored. The electrical activity may then be utilized to determine whether the cardiac conduction system of the patient has been captured by the VfA therapy.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: July 11, 2023
    Assignee: Medtronic, Inc.
    Inventor: Subham Ghosh
  • Publication number: 20230172521
    Abstract: Determination of cardiac conduction system pacing therapy benefit may be performed by the systems, methods, devices, and interfaces described herein. For example, various metrics of activation time dispersion may be generated based on electrical activity monitored by a plurality of external electrodes such as, e.g., a left-sided metric of dispersion and a global metric of dispersion. Such various metrics of activation time dispersion may be used to determined whether cardiac conduction system pacing would be beneficial.
    Type: Application
    Filed: October 20, 2022
    Publication date: June 8, 2023
    Inventor: Subham Ghosh
  • Publication number: 20230149719
    Abstract: Systems and methods are described herein for configuration of cardiac therapy. The systems and methods may select, or determine, a plurality of different configuration parameters based electrical activity monitored or measured using a plurality of external electrodes. For example, the systems and methods may select, or determine, a left ventricular pacing vector, adaptive or non-adaptive pacing therapy, an interventricular pacing delay, and a atrioventricular pacing delay.
    Type: Application
    Filed: November 8, 2022
    Publication date: May 18, 2023
    Inventors: Subham Ghosh, Elizabeth A. Schotzko
  • Patent number: 11648406
    Abstract: Systems, methods, and interfaces are described herein for identification of effective electrodes to be used in sensing and/or therapy. Two or more portions of a signal monitored using an electrode may be compared to determine whether the electrode is effective. The two or more portions may correspond to the same portion or window of a cardiac cycle. Further, signals from a first electrode and from a second electrode located proximate the first electrode may be compared to determine whether one or both of the electrodes are effective.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: May 16, 2023
    Assignee: Medtronic, Inc.
    Inventors: Subham Ghosh, Jeffrey Gillberg