Patents by Inventor Subhash Chandra Taneja
Subhash Chandra Taneja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9073860Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2 (E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: GrantFiled: October 11, 2013Date of Patent: July 7, 2015Assignee: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Surrinder Koul, Jawahir Lal Koul, Subhash Chandra Taneja, Pankaj Gupta, Inshad Ali Khan, Zahid Mehmood Mirza, Ashwani Kumar, Rakesh Kamal Johri, Monika Pandita, Anita Khosa, Ashok Kumar Tikoo, Subhash Chander Sharma, Vijeshwar Verma, Ghulam Nabi Qazi
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Publication number: 20140073595Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: ApplicationFiled: October 11, 2013Publication date: March 13, 2014Applicant: Council Of Scientific and Industrial ResearchInventors: Surrinder KOUL, Jawahir Lal KOUL, Subhash Chandra TANEJA, Pankaj GUPTA, Inshad Ali KHAN, Zahid Mehmood MIRZA, Ashwani KUMAR, Rakesh Kamal JOHRI, Monika PANDITA, Anita KHOSA, Ashok Kumar TIKOO, Subhash Chander Sharma, Vijeshwar VERMA, Ghulam Nabi QAZI
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Patent number: 8609858Abstract: The present invention relates to novel spiro derivatives of parthenin prepared by the dipolar cycloaddition of various dipoles viz, benzonitrile oxides, nitrones, azides, nitrile ylide diazoalkane, nitrile imide, ozone, azomethine imides, azomethine ylides etc. with exocyclic double bond of C ring (?-methylene-?-butyrolactone). Representative compounds have been screened for their anticancer activity against different cancer cell lines. ICs0 value of these analogues varies between 4.3 ?M to 93 ?M. A mechanistic correlation of their anticancer activity has been described. The results of the cytotoxicity test of the compounds studies indicated that the ?,?-unsaturated ketonic moiety in parthenin plays an important role in the maintenance of the high level of cytotoxicity.Type: GrantFiled: March 5, 2009Date of Patent: December 17, 2013Assignee: Council of Scientific & Industrial ResearchInventors: Mahabalarao Sampath Kumar Halmuthur, Ajit Kumar Saxena, Subhash Chandra Taneja, Shashank Kumar Singh, Vijay Kumar Sethi, Naveed Ahmed Qazi, Sanghapal Damodhar Sawant, Mahendhar Reddy Doma, Abid Hussain Banday, Monika Verma, Ghularn Nabi Qazi
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Patent number: 8580752Abstract: The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.Type: GrantFiled: March 29, 2006Date of Patent: November 12, 2013Assignee: Council of Scientitic and Industrial ResearchInventors: Surrinder Koul, Jawahir Lal Koul, Subhash Chandra Taneja, Pankaj Gupta, Inshad Ali Khan, Zahid Mehmood Mirza, Ashwani Kumar, Rakesh Kamal Johri, Monika Pandita, Anita Khosa, Ashok Kumar Tikoo, Subhash Chander Sharma, Vijeshwar Verma, Ghulam Nabi Qazi
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Patent number: 8445700Abstract: The present invention relates to a facile, highly efficient and economical process for the preparation of optically active N-benzyl-3-hydroxypyrrolidine in high yield from a naturally occurring alkaloid vasicine. The natural alkaloid vasicine is used as a precursor of (S)—N-benzyl-3-hydroxypyrrolidine and (R)—N-benzyl-3-hydroxypyrrolidines which can easily be sourced from the medicinal plant Adatoda vasica by the method known in the art and transformed to optical isomers (R) and (S)—N-benzyl-3-hydroxypyrrolidine by the method described in the present invention.Type: GrantFiled: November 24, 2009Date of Patent: May 21, 2013Assignee: Council of Scientific & Industrial ResearchInventors: Subhash Chandra Taneja, Mushtaq Ahmad Aga, Brijesh Kumar, Vijay Kumar Sethi, Samar Singh Andotra, Ghulam Nabi Qazi
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Publication number: 20120101285Abstract: The present invention relates to a facile, highly efficient and economical process for the preparation of optically active N-benzyl-3-hydroxypyrrolidine in high yield from a naturally occurring alkaloid vasicine. The natural alkaloid vasicine is used as a precursor of (S)—N-benzyl-3-hydroxypyrrolidine and (R)—N-benzyl-3-hydroxypyrrolidines which can easily be sourced from the medicinal plant Adatoda vasica by the method known in the art and transformed to optical isomers (R) and (S)—N-benzyl-3-hydroxypyrrolidine by the method described in the present invention.Type: ApplicationFiled: November 24, 2009Publication date: April 26, 2012Inventors: Subhash Chandra Taneja, Mushtaq Ahmad Aga, Brijesh Kumar, Vijay Kumar Sethi, Samar Singh Andotra, Ghulam Nabi Qazi
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Publication number: 20110201661Abstract: The present invention relates to novel spiro derivatives of parthenin prepared by the dipolar cycloaddition of various dipoles viz, benzonitrile oxides, nitrones, azides, nitrile ylide diazoalkane, nitrile imide, ozone, azomethine imides, azomethine ylides etc. with exocyclic double bond of C ring (?-methylene-?-butyrolactone). Representative compounds have been screened for their anticancer activity against different cancer cell lines. ICs0 value of these analogues varies between 4.3 ?M to 93 ?M. A mechanistic correlation of their anticancer activity has been described. The results of the cytotoxicity test of the compounds studies indicated that the ?,?-unsaturated ketonic moiety in parthenin plays an important role in the maintenance of the high level of cytotoxicity.Type: ApplicationFiled: March 5, 2009Publication date: August 18, 2011Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Mahabalarao Sampath Kumar Halmuthur, Ajit Kumar Saxena, Subhash Chandra Taneja, Shashank Kumar Singh, Vijay Kumar Sethi, Naveed Ahmed Qazi, Sanghapal Damodhar Sawant, Mahendhar Reddy Doma, Abid Hussain Banday, Monika Verma, Ghularn Nabi Qazi
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Publication number: 20090298938Abstract: The present invention relates to use of compounds of general formula 1 for anticancerous activity, wherein the said compound being derived semi-synthetically from natural triterpenoic acids known as boswellic acids by the induction of apoptosis thereof cytotoxicity and anti-cancer activity displayed by semi-synthetic analogues of natural triterpenes, known as Boswellic acids. These compounds may be used for the treatment of cancer, alone or in combination with pharmaceutically acceptable or other carriers, displaying cytotoxicity and anti-cancer activity for colon, prostrate, liver, breast, central nervous system (CNS), leukemia and malignancy of other tissues, including ascites and solid tumors. The cancer cell death is mediated by induction of apoptosis and inhibition of cell proliferation at specific doses.Type: ApplicationFiled: March 10, 2009Publication date: December 3, 2009Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Ghulam Nabi Qazi, Subhash Chandra Taneja, Jaswant Singh, Ajit Kumar Saxena, Vijay Kumar Sethi, Bhahwal Ali Shah, Bal Krishan Kapahi, Samar Singh Andotra, Ajay Kumar, Shashi Bhushan, Fayaz Malik, Dilip Manikrao Mondhe, Shanmugavel Muthiah, Surjeet Singh, Monika Verma, Shashank Kumar Singh
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Patent number: 7262296Abstract: The present invention relates to novel compounds possessing specific hot, pungent and spicy taste when subjected to direct pungency evaluation, which may be useful as food additives and anti-oxidants, however the said compounds do not add to any nutritional value but the synthesised compounds can possess useful pharmacological properties which is expected to find application in new test models for the development of anti-inflammatory drugs, bioavailability enhancers and for the study of hepatic drug metabolising mechanism; also relates to a process for preparing the said compounds.Type: GrantFiled: December 15, 2005Date of Patent: August 28, 2007Assignee: Council of Scientific and Industrial ResearchInventors: Subhash Chandra Taneja, Surrinder Koul, Jawahir Lal Koul, Beenu Moza, Sukhdev Swami Handa
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Patent number: 7166728Abstract: The present invention relates to a process for the synthesis of racemic nerol oxide i.e. 3,6-dihydro-4-methyl-2-[2-methyl-1-propenyl)-2H-pyran from monoterpene alcohol nerol i.e. cis-3,7-dimethylocta-2,6-diene-1-ol.Type: GrantFiled: December 28, 2004Date of Patent: January 23, 2007Assignee: Council of Scientific and Industrial ResearchInventors: Vijay Kumar Sethi, Samar Singh Andotra, Subhash Chandra Taneja, Pankaj Gupta, Ghulam Nabi Qazi
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Patent number: 7153983Abstract: The present invention relates to a novel synthetic process for the enriched preparation of substituted R(+)?-benzyl-?-butyrolactone (1) as shown in the drawing wherein R1 and R2 independently or in combination represent the following groups: i.e.Type: GrantFiled: March 3, 2003Date of Patent: December 26, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Subhash Chandra Taneja, Surrinder Kaul, Buddh Singh, Ghulam Nabi Qazi
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Patent number: 7060471Abstract: The present invention relates to a novel and efficient chemoenzymatic process of preparation of optically active trans alkyl phenylglycidates. The invention particularly discloses a novel process for the chemoenzymatic synthesis of two enantiomers of trans alkyl phenylglycidate i.e.Type: GrantFiled: March 10, 2004Date of Patent: June 13, 2006Assignee: Council of Scientific & Industrial ResearchInventors: Naveen Anand, Munish Kapoor, Subhash Chandra Taneja, Surrinder Koul, Rattan Lal Sharma, Ghulam Nabi Qazi
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Patent number: 7057040Abstract: The present invention relates to novel compounds possessing specific hot, pungent and spicy taste when subjected to direct pungency evaluation, which may be useful as food additives and anti-oxidants, however the said compounds do not add to any nutritional value but the synthesised compounds can possess useful pharmacological properties which is expected to find application in new test models for the development of anti-inflammatory drugs, bioavailability enhancers and for the study of hepatic drug metabolising mechanism; also relates to a process for preparing the said compounds.Type: GrantFiled: February 7, 2002Date of Patent: June 6, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Subhash Chandra Taneja, Surrinder Koul, Jawahir Lal Koul, Beenu Moza, Sukhdev Swami Handa
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Publication number: 20040259943Abstract: The present invention relates to a novel and efficient chemoenzymatic process of preparation of optically active trans alkyl phenylglycidates. The invention particularly discloses a novel process for the chemoenzymatic synthesis of two enantiomers of trans alkyl phenylglycidate i.e. alkyl(2S,3R)-phenylglycidate and alkyl(2R,3S)-phenylglycidate of formulae 7 and 8 respectively.Type: ApplicationFiled: March 10, 2004Publication date: December 23, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIALInventors: Naveen Anand, Munish Kapoor, Subhash Chandra Taneja, Surrinder Koul, Rattan Lal Sharma, Ghulam Nabi Oazi
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Patent number: 6787674Abstract: The present invention relates to anti-microbial activity of the essential oil of Cymbopogon flexuosus (Nees ex Steud) Wats and the process of isolation of novel sesquiterpene compound which is mainly responsible for the strong anti-microbial/anti-bacterial activity. The present invention particularly relates to anti-bacterial activity of the essential oil and a pure isolate identified as (+)-1-bisabolone of formula 1 against gram positive bacteria from a strain of a grass identified as Cymbopogon flexuosus.Type: GrantFiled: March 27, 2003Date of Patent: September 7, 2004Assignee: Council of Scientific and Industrial ResearchInventors: Subhash Chandra Taneja, Ashok Kumar Shahi, Vijeshwar Verma, Vijay Kumar Sethi, Samar Singh Andotra, Abid Zaffar Hashmi, Prabhu Dutt, Sanotosh Kumar Bakshi, Maharaj Krishan Koul, Satya Narayan Sharma, Suresh Chandra, Ghulam Nabi Qazi
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Publication number: 20040014993Abstract: The present invention relates to a novel process for the preparation of optically enriched substituted R(+)&bgr;-benzyl-&ggr;-butyrolactones of the general formula 1, 1Type: ApplicationFiled: March 3, 2003Publication date: January 22, 2004Applicant: Council of Scientific and Industrial ResearchInventors: Subhash Chandra Taneja, Surrinder Kaul, Buddh Singh, Ghulam Nabi Qazi
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Patent number: 6664236Abstract: The present invention provides a synergistic composition of bioactive fraction essentially constituting iridoid glucosides, acetyl barlerin and shanzhiside methyl ester isolated from a plant source Barleria prionitis linn along with a process for the isolation of the bioactive fraction, the present invention also relates to a method of treating mammals and humans for hepatotoxicity, stress and immuno-deficiency with the synergistic bioactive composition.Type: GrantFiled: March 19, 2002Date of Patent: December 16, 2003Assignee: Council of Scientific and Industrial ResearchInventors: J. L. Suri, S. K. Banerjee, Subhash Chandra Taneja, A. S. Anand, Anil Prabhakar, Bupinder Singh Jaggi, A. K. Saxena, Bal Krishan Chandan, Sukhdev Swami Handa
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Publication number: 20030181397Abstract: The present invention provides a synergistic composition of bioactive fraction essentially constituting iridoid glucosides, acetyl barlerin and shanzhiside methyl ester isolated from a plant source Barleria prionitis linn along with a process for the isolation of the bioactive fraction, the present invention also relates to a method of treating mammals and humans for hepatotoxicity, stress and immuno-deficiency with the synergistic bioactive composition.Type: ApplicationFiled: March 19, 2002Publication date: September 25, 2003Applicant: Council of Scientific and Industrial ResearchInventors: J.L. Suri, S.K. Banerjee, Subhash Chandra Taneja, A.S. Anand, Anil Prabhakar, Bupinder Singh Jaggi, A.K. Saxena, Bal Krishan Chandan, Sukhdev Swami Handa
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Publication number: 20030161860Abstract: The present invention relates to novel compounds possessing specific hot, pungent and spicy taste when subjected to direct pungency evaluation, which may be useful as food additives and anti-oxidants, however the said compounds do not add to any nutritional value but the synthesised compounds can possess useful pharmacological properties which is expected to find application in new test models for the development of anti-inflammatory drugs, bioavailability enhancers and for the study of hepatic drug metabolising mechanism; also relates to a process for preparing the said compounds.Type: ApplicationFiled: February 7, 2002Publication date: August 28, 2003Inventors: Subhash Chandra Taneja, Surrinder Koul, Jawahir Lal Koul, Beenu Moza, Sukhdev Swami Handa
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Patent number: PP15595Abstract: A new and distinct variety of Cymbopogon commutatus grass is provided. The new variety was discovered during a mass selection program that was carried out in India in a cultivated area, and offers significant advantages over a typical plant of the species. More specifically, the new variety exhibits superior drought tolerance, a vigorous perennial growth habit, and lighter green leaves than typically exhibited by the species. The plant produces an essential oil having an enhanced geraniol and geranyl acetate content that is useful to form perfumes and in flavor applications. Asexual reproduction can be readily carried out by the rooting of slips.Type: GrantFiled: February 8, 2002Date of Patent: March 1, 2005Assignee: Council of Scientific and Industrial ResearchInventors: Ashok Kumar Shahi, Satya Narayan Sharma, Swadesh Pal, Suresh Chandra, Prabhu Dutt, Surendra Singh Balyan, Maharaj Krishen Bhan, Subhash Chandra Taneja, Ravinder Kumar Raina, Vijeshwar Verma, Shazia Zahoor, Maharaj Krishen Kaul, Ghulam Nabi Qazi