Patents by Inventor Subhrajit Saha

Subhrajit Saha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating radiation induced gastrointestinal syndrome (RIGS) and related disease states using YEL002/BCN057
    Patent number: 11364231
    Abstract: The present disclosure is directed to method of treatment for treating or ameliorating various conditions caused by radiation exposure such as RIGS, enteritis, oral mucositis, mucositis, and proctitis by the administration of a compound Yel002/BCN057 or an analog thereof.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: June 21, 2022
    Assignees: University of Kansas, BCN Biosciences L.L.C.
    Inventors: Subhrajit Saha, Andrew J. Norris
  • METHODS OF TREATING RADIATION INDUCED GASTROINTESTINAL SYNDROME (RIGS) AND RELATED DISEASE STATES USING YEL002/BCN057
    Publication number: 20200368222
    Abstract: The present disclosure is directed to method of treatment for treating or ameliorating various conditions caused by radiation exposure such as RIGS, enteritis, oral mucositis, mucositis, and proctitis by the administration of a compound Yel002/BCN057 or an analog thereof.
    Type: Application
    Filed: May 8, 2020
    Publication date: November 26, 2020
    Applicants: University of Kansas, BCN Biosciences L.L.C.
    Inventors: Subhrajit Saha, Andrew J. Norris
  • METHODS OF TREATING RADIATION INDUCED GASTROINTESTINAL SYNDROME (RIGS) AND RELATED DISEASE STATES USING YEL002/BCN057
    Publication number: 20190381030
    Abstract: The present disclosure is directed to method of treatment for treating or ameliorating various conditions caused by radiation exposure such as RIGS, enteritis, oral mucositis, mucositis, and proctitis by the administration of a compound Yel002/BCN057 or an analog thereof.
    Type: Application
    Filed: October 12, 2018
    Publication date: December 19, 2019
    Applicants: University of Kansas, BCN Biosciences L.L.C.
    Inventors: Subhrajit Saha, Andrew J. Norris
  • Stromal cell therapy in treatment of radiation injury
    Patent number: 9782441
    Abstract: Methods are provided for treating, mitigating or protecting from radiation-induced injury using bone marrow stromal cells expanded in culture, adipose-tissue derived non-adherent stromal cells, or the culture supernatant thereof.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: October 10, 2017
    Assignee: Albert Einstein College of Medicine, Inc.
    Inventors: Chandan Guha, Subhrajit Saha, Alan A. Alfieri, Payel Bhanja
  • Therapy for radiation-induced lung injury
    Patent number: 9439947
    Abstract: Methods are disclosed for therapy of radiation-induced lung injury and other lung diseases using R-spondin1.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: September 13, 2016
    Assignee: Albert Einstein College of Medicine, Inc.
    Inventors: Chandan Guha, Subhrajit Saha
  • WNT MODULATORS FOR THE PROTECTION, MITIGATION AND TREATMENT OF RADIATION INJURY
    Publication number: 20160074400
    Abstract: Provided are composition and methods for treating radiation-induced cell damage, and in particular aspects to methods for protecting, mitigating or otherwise treating radiation-induced induced depletion of tissue stem cells and injury to the supportive stem cell niche, and in even more particular aspects to methods for protecting, mitigating or otherwise treating radiation-induced gastrointestinal syndrome (RIGS), comprising sequential administration of a Wnt pathway activator/agonist (e.g., Rspo1 or a small molecule inducer thereof) that amplifies the surviving intestinal stem cell (ISC) pool post-radiation exposure, followed by a selective antagonist of the ?-Catenin-CBP interaction (e.g., ICG-001 or other exemplary compounds disclosed herein) that accelerates differentiation of the stimulated (e.g., Rspo1-stimulated) ISC in crypt-villi axis, promoting villous regeneration and intestinal restitution, thereby mitigating RIGS. Adjunctive and combination therapy embodiments are encompassed.
    Type: Application
    Filed: August 6, 2013
    Publication date: March 17, 2016
    Inventors: Michael Kahn, Chandan Guha, Subhrajit Saha, Payel Bhanja
  • THERAPY FOR RADIATION-INDUCED LUNG INJURY
    Publication number: 20150306177
    Abstract: Methods are disclosed for therapy of radiation-induced lung injury and other lung diseases using R-spondin1.
    Type: Application
    Filed: March 24, 2015
    Publication date: October 29, 2015
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
    Inventors: Chandan Guha, Subhrajit Saha
  • STROMAL CELL THERAPY IN TREATMENT OF RADIATION INJURY
    Publication number: 20150118206
    Abstract: Methods are provided for treating, mitigating or protecting from radiation-induced injury using bone marrow stromal cells expanded in culture, adipose-tissue derived non-adherent stromal cells, or the culture supernatant thereof.
    Type: Application
    Filed: July 10, 2012
    Publication date: April 30, 2015
    Inventors: Chandan Guha, Subhrajit Saha, Alan Alfieri, Payel Bhanja