Patents by Inventor Subramaniam Sriram

Subramaniam Sriram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210308152
    Abstract: Methods for stimulating neural repair and remyelination and for treating a myelin related disorder in a subject are described. The methods include administering to a subject in need of treatment an effective amount of anacardic acid having the formula (I) of claim 1 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 12, 2019
    Publication date: October 7, 2021
    Inventor: Subramaniam SRIRAM
  • Patent number: 8686365
    Abstract: Optical imaging structures and methods are disclosed. One structure may be implemented as an imaging pixel having multiple photodetectors. The photodetectors may detect different wavelengths of incident radiation, and may be operated simultaneously or at separate times. An imager may include an imaging array of pixels of the type described. Methods of operating such structures are also described.
    Type: Grant
    Filed: July 27, 2009
    Date of Patent: April 1, 2014
    Assignee: Infrared Newco, Inc.
    Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
  • Patent number: 8294100
    Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: October 23, 2012
    Assignee: Infrared Newco, Inc.
    Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
  • Publication number: 20120061567
    Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.
    Type: Application
    Filed: November 18, 2011
    Publication date: March 15, 2012
    Applicant: Infrared Newco, Inc.
    Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
  • Patent number: 8084739
    Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: December 27, 2011
    Assignee: Infrared Newco., Inc.
    Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
  • Publication number: 20100019154
    Abstract: Optical imaging structures and methods are disclosed. One structure may be implemented as an imaging pixel having multiple photodetectors. The photodetectors may detect different wavelengths of incident radiation, and may be operated simultaneously or at separate times. An imager may include an imaging array of pixels of the type described. Methods of operating such structures are also described.
    Type: Application
    Filed: July 27, 2009
    Publication date: January 28, 2010
    Applicant: Noble Peak Vision Corp.
    Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
  • Publication number: 20100012841
    Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.
    Type: Application
    Filed: July 16, 2009
    Publication date: January 21, 2010
    Applicant: Noble Peak Vision Corp.
    Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
  • Patent number: 7094397
    Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: August 22, 2006
    Assignee: Vanderbilt Unversity
    Inventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
  • Publication number: 20050171069
    Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.
    Type: Application
    Filed: February 17, 2005
    Publication date: August 4, 2005
    Applicant: Vanderbilt University
    Inventors: Charles Stratton, William Mitchell, Subramaniam Sriram
  • Patent number: 6890526
    Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: May 10, 2005
    Assignee: Vanderbilt University
    Inventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
  • Publication number: 20040180063
    Abstract: The present invention provides immunogenic oligopeptides derived from the Major Histocompatibility Complex (MHC) glycoprotein protein sequences for use in compositions and methods for the treatment, prevention and diagnosis of deleterious immune responses, such as autoimmunity and allergies. The peptides are capable of inducing an immune response against glycoproteins encoded MHC alleles associated with the target disease. In preferred embodiments the peptides of the invention are derived from hypervariable region of the &bgr; chain of an MHC Class II molecule associated with the deleterious immune response.
    Type: Application
    Filed: February 15, 2002
    Publication date: September 16, 2004
    Inventors: Subramaniam Sriram, Bishwajit Nag, Somesh D. Sharma
  • Patent number: 6710033
    Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: March 23, 2004
    Assignee: Vanderbilt University
    Inventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
  • Publication number: 20030223959
    Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.
    Type: Application
    Filed: April 17, 2003
    Publication date: December 4, 2003
    Inventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
  • Patent number: 6555702
    Abstract: A compound of the formula I: wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy, alkoxy of 1-6 carbon atoms —CO2Z, —O(CH2)mCO2Z, —SO3Z, —OPO3Z2; and Y is cyano,   —C(NR1R2)═C(CN)2; wherein X═O or S, and R1 and R2 are independently H, benzyl, —CH(CH3)C6H6, —(CH2)n C6H6, phenyl; —CO2R; n=2-4; R is lower alkyl of 1-6 carbon atoms; m=1-4 and Z is H, a cation or lower alkyl of 1-6 cabon atoms; is used for treating inflammation, immunological diseases or diabetes.
    Type: Grant
    Filed: April 3, 1998
    Date of Patent: April 29, 2003
    Assignee: Calyx Therapeutics, Inc.
    Inventors: Subramaniam Sriram, John Bright, Bishwajit Nag, Somesh D. Sharma
  • Publication number: 20020115714
    Abstract: A compound of the formula I: 1
    Type: Application
    Filed: April 3, 1998
    Publication date: August 22, 2002
    Inventors: SUBRAMANIAM SRIRAM, JOHN BRIGHT, BISHWAJIT NAG, SOMESH D. SHARMA
  • Patent number: 6194453
    Abstract: Disclosed herein are compounds of the formula I wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy or alkoxy of 1-6 carbon atoms; and Y is cyano,  —C(NR1 R2)═C(CN)2; wherein X═O or S, and R1 and R2 are independently  H, benzyl, —CH(CH3)C6H6,  —(CH2)nC6H6, phenyl; —CO2R;  n=2-4; R is lower alkyl of 1-6 carbon atoms which are useful for treating inflammation and immunological diseases.
    Type: Grant
    Filed: December 21, 1998
    Date of Patent: February 27, 2001
    Assignee: Calyx Therapeutics, Inc.
    Inventors: Subramaniam Sriram, John Bright, Bishwajit Nag, Somesh D. Sharma
  • Patent number: 6045796
    Abstract: The present invention provides immunogenic oligopeptides derived from the Major Histocompatibility Complex (MHC) glycoprotein protein sequences for use in compositions and methods for the treatment, prevention and diagnosis of deleterious immune responses, such as autoimmunity and allergies. The peptides are capable of inducing an immune response against glycoproteins encoded MHC alleles associated with the target disease. In preferred embodiments the peptides of the invention are derived from hypervariable region of the .beta. chain of an MHC Class II molecule associated with the deleterious immune response.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 4, 2000
    Assignee: Anergen, Inc.
    Inventors: Subramaniam Sriram, Bishwajit Nag, Somesh D. Sharma
  • Patent number: 5854285
    Abstract: A compound of the formula I ##STR1## wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms;B is hydroxy or alkoxy of 1-6 carbon atoms; andY is cyano, ##STR2##--C(NR.sub.1 R.sub.2).dbd.C(CN).sub.2 ;wherein X=O or S, and R.sub.1 and R.sub.2 are independently H, benzyl, --CH(CH.sub.3), C.sub.6 H.sub.5--(CH.sub.2).sub.n C.sub.6 H.sub.6, phenyl; --CO.sub.2 R;n=2-4; R is lower alkyl of 1-6 carbon atomsis used for treating inflammation and immunological diseases.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: December 29, 1998
    Assignee: Natpro, Inc.
    Inventors: Subramaniam Sriram, John Bright, Bishwajit Nag, Somesh D. Sharma
  • Patent number: 5660828
    Abstract: A method to block cytolytic activity of CD8 phenotype T cells using an effective amount of a complement-fixing anti CD8 antibody is described. The anti CD8 antibody may be used to treat patients with immunopathologic disorders induced by viruses or (autoimmune diseases) such as multiple sclerosis, viral or post-viral polyneuropathy, viral or post-viral myocarditis, insulitis, encephalomyelitis, myositis, synovitus, and arthritis.
    Type: Grant
    Filed: January 6, 1994
    Date of Patent: August 26, 1997
    Assignees: Mayo Foundation for Medical Education & Research, University of Vermont and State Agricultural College
    Inventors: Moses Rodriguez, Subramaniam Sriram