Patents by Inventor Subramaniam Sriram
Subramaniam Sriram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210308152Abstract: Methods for stimulating neural repair and remyelination and for treating a myelin related disorder in a subject are described. The methods include administering to a subject in need of treatment an effective amount of anacardic acid having the formula (I) of claim 1 or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: August 12, 2019Publication date: October 7, 2021Inventor: Subramaniam SRIRAM
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Patent number: 8686365Abstract: Optical imaging structures and methods are disclosed. One structure may be implemented as an imaging pixel having multiple photodetectors. The photodetectors may detect different wavelengths of incident radiation, and may be operated simultaneously or at separate times. An imager may include an imaging array of pixels of the type described. Methods of operating such structures are also described.Type: GrantFiled: July 27, 2009Date of Patent: April 1, 2014Assignee: Infrared Newco, Inc.Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
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Patent number: 8294100Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.Type: GrantFiled: November 18, 2011Date of Patent: October 23, 2012Assignee: Infrared Newco, Inc.Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
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Publication number: 20120061567Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.Type: ApplicationFiled: November 18, 2011Publication date: March 15, 2012Applicant: Infrared Newco, Inc.Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
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Patent number: 8084739Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.Type: GrantFiled: July 16, 2009Date of Patent: December 27, 2011Assignee: Infrared Newco., Inc.Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
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Publication number: 20100019154Abstract: Optical imaging structures and methods are disclosed. One structure may be implemented as an imaging pixel having multiple photodetectors. The photodetectors may detect different wavelengths of incident radiation, and may be operated simultaneously or at separate times. An imager may include an imaging array of pixels of the type described. Methods of operating such structures are also described.Type: ApplicationFiled: July 27, 2009Publication date: January 28, 2010Applicant: Noble Peak Vision Corp.Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
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Publication number: 20100012841Abstract: Imagers, pixels, and methods of using the same are disclosed for imaging in various spectra, such as visible, near infrared (IR), and short wavelength IR (SWIR). The imager may have an imaging array having pixels of different types. The different types of pixels may detect different ranges of wavelengths in the IR, or the SWIR, spectra. The pixels may include a filter which blocks some wavelengths of radiation in the IR spectrum while passing other wavelengths. The filter may be formed of a semiconductor material, and therefore may be easily integrated with a CMOS pixel using conventional CMOS processing techniques.Type: ApplicationFiled: July 16, 2009Publication date: January 21, 2010Applicant: Noble Peak Vision Corp.Inventors: Conor S. Rafferty, Anders Ingvar Aberg, Tirunelveli Subramaniam Sriram, Bryan D. Ackland, Clifford A. King
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Patent number: 7094397Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.Type: GrantFiled: February 17, 2005Date of Patent: August 22, 2006Assignee: Vanderbilt UnversityInventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
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Publication number: 20050171069Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.Type: ApplicationFiled: February 17, 2005Publication date: August 4, 2005Applicant: Vanderbilt UniversityInventors: Charles Stratton, William Mitchell, Subramaniam Sriram
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Patent number: 6890526Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.Type: GrantFiled: April 17, 2003Date of Patent: May 10, 2005Assignee: Vanderbilt UniversityInventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
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Publication number: 20040180063Abstract: The present invention provides immunogenic oligopeptides derived from the Major Histocompatibility Complex (MHC) glycoprotein protein sequences for use in compositions and methods for the treatment, prevention and diagnosis of deleterious immune responses, such as autoimmunity and allergies. The peptides are capable of inducing an immune response against glycoproteins encoded MHC alleles associated with the target disease. In preferred embodiments the peptides of the invention are derived from hypervariable region of the &bgr; chain of an MHC Class II molecule associated with the deleterious immune response.Type: ApplicationFiled: February 15, 2002Publication date: September 16, 2004Inventors: Subramaniam Sriram, Bishwajit Nag, Somesh D. Sharma
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Patent number: 6710033Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.Type: GrantFiled: March 17, 2000Date of Patent: March 23, 2004Assignee: Vanderbilt UniversityInventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
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Publication number: 20030223959Abstract: The invention features methods and reagents for the diagnosis, monitoring, and treatment of multiple sclerosis. The invention is based in part on the discovery that Chlamydia is present in patients with multiple sclerosis, and that anti-chlamydial agents improve or sustain neurological function in these patients.Type: ApplicationFiled: April 17, 2003Publication date: December 4, 2003Inventors: Charles W. Stratton, William M. Mitchell, Subramaniam Sriram
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Patent number: 6555702Abstract: A compound of the formula I: wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy, alkoxy of 1-6 carbon atoms —CO2Z, —O(CH2)mCO2Z, —SO3Z, —OPO3Z2; and Y is cyano, —C(NR1R2)═C(CN)2; wherein X═O or S, and R1 and R2 are independently H, benzyl, —CH(CH3)C6H6, —(CH2)n C6H6, phenyl; —CO2R; n=2-4; R is lower alkyl of 1-6 carbon atoms; m=1-4 and Z is H, a cation or lower alkyl of 1-6 cabon atoms; is used for treating inflammation, immunological diseases or diabetes.Type: GrantFiled: April 3, 1998Date of Patent: April 29, 2003Assignee: Calyx Therapeutics, Inc.Inventors: Subramaniam Sriram, John Bright, Bishwajit Nag, Somesh D. Sharma
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Publication number: 20020115714Abstract: A compound of the formula I: 1Type: ApplicationFiled: April 3, 1998Publication date: August 22, 2002Inventors: SUBRAMANIAM SRIRAM, JOHN BRIGHT, BISHWAJIT NAG, SOMESH D. SHARMA
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Patent number: 6194453Abstract: Disclosed herein are compounds of the formula I wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms; B is hydroxy or alkoxy of 1-6 carbon atoms; and Y is cyano, —C(NR1 R2)═C(CN)2; wherein X═O or S, and R1 and R2 are independently H, benzyl, —CH(CH3)C6H6, —(CH2)nC6H6, phenyl; —CO2R; n=2-4; R is lower alkyl of 1-6 carbon atoms which are useful for treating inflammation and immunological diseases.Type: GrantFiled: December 21, 1998Date of Patent: February 27, 2001Assignee: Calyx Therapeutics, Inc.Inventors: Subramaniam Sriram, John Bright, Bishwajit Nag, Somesh D. Sharma
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Patent number: 6045796Abstract: The present invention provides immunogenic oligopeptides derived from the Major Histocompatibility Complex (MHC) glycoprotein protein sequences for use in compositions and methods for the treatment, prevention and diagnosis of deleterious immune responses, such as autoimmunity and allergies. The peptides are capable of inducing an immune response against glycoproteins encoded MHC alleles associated with the target disease. In preferred embodiments the peptides of the invention are derived from hypervariable region of the .beta. chain of an MHC Class II molecule associated with the deleterious immune response.Type: GrantFiled: June 7, 1995Date of Patent: April 4, 2000Assignee: Anergen, Inc.Inventors: Subramaniam Sriram, Bishwajit Nag, Somesh D. Sharma
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Patent number: 5854285Abstract: A compound of the formula I ##STR1## wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms;B is hydroxy or alkoxy of 1-6 carbon atoms; andY is cyano, ##STR2##--C(NR.sub.1 R.sub.2).dbd.C(CN).sub.2 ;wherein X=O or S, and R.sub.1 and R.sub.2 are independently H, benzyl, --CH(CH.sub.3), C.sub.6 H.sub.5--(CH.sub.2).sub.n C.sub.6 H.sub.6, phenyl; --CO.sub.2 R;n=2-4; R is lower alkyl of 1-6 carbon atomsis used for treating inflammation and immunological diseases.Type: GrantFiled: April 3, 1997Date of Patent: December 29, 1998Assignee: Natpro, Inc.Inventors: Subramaniam Sriram, John Bright, Bishwajit Nag, Somesh D. Sharma
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Patent number: 5660828Abstract: A method to block cytolytic activity of CD8 phenotype T cells using an effective amount of a complement-fixing anti CD8 antibody is described. The anti CD8 antibody may be used to treat patients with immunopathologic disorders induced by viruses or (autoimmune diseases) such as multiple sclerosis, viral or post-viral polyneuropathy, viral or post-viral myocarditis, insulitis, encephalomyelitis, myositis, synovitus, and arthritis.Type: GrantFiled: January 6, 1994Date of Patent: August 26, 1997Assignees: Mayo Foundation for Medical Education & Research, University of Vermont and State Agricultural CollegeInventors: Moses Rodriguez, Subramaniam Sriram