Patents by Inventor Sudarsanareddy LOKIREDDY

Sudarsanareddy LOKIREDDY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR CONTINUOUS PRODUCTION OF RECOMBINANT GLP-1 PEPTIDE BY BACTERIA
    Publication number: 20220127324
    Abstract: The invention relates to a method for continuously producing and secreting recombinant Glucagon-like peptide-1 (GLP-1) by bacteria, more specifically E. coli. More specifically, the invention relates to use of novel bacterial expression vector for producing and enabling extracellular secretion of GLP-1, use of novel media composition for enhancing the secretion and enabling purification, and a perfusion-based fermentation system for continuous production and separation of recombinant GLP-1 peptide.
    Type: Application
    Filed: February 24, 2020
    Publication date: April 28, 2022
    Applicant: ONCOSIMIS BIOTECH PRIVATE LIMITED
    Inventors: SUDARSANAREDDY LOKIREDDY, VENKATA SRI KRISHNA KONA
  • BACTERIAL EXPRESSION VECTOR FOR ENHANCED PROTEIN SECRETION
    Publication number: 20220025383
    Abstract: The invention provides a bacterial expression vector (100) comprising of a secretory signal sequence in tandem with DNA sequence encoding recombinant protein (103), wherein, the secretory signal sequence is a combination comprising of: a) at least one DNA sequence encoding a signal sequence (101) of gene selected from the group consisting of pelB, ompA, yebF, and ompF, and b) at least one DNA sequence encoding a carrier peptide (102) selected from the group consisting of Seq. ID 5 and 6 encoding truncated yebF.
    Type: Application
    Filed: February 15, 2020
    Publication date: January 27, 2022
    Applicant: ONCOSIMIS BIOTECH PRIVATE LIMITED
    Inventor: Sudarsanareddy LOKIREDDY