Patents by Inventor Sudershan K. Arora
Sudershan K. Arora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100113371Abstract: The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds of this invention can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and autoimmune diseases, for example, bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection or psoriasis. The present invention also relates to pharmacological compositions containing these monosaccharide derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection, and other inflammatory and/or auto immune disorders.Type: ApplicationFiled: December 22, 2005Publication date: May 6, 2010Applicant: RANBAXY LABORATORIES LIMITED INC.Inventors: Viswajanani Jitendra Sattigeri, Sudershan K. Arora, Mohammad Salman, Venkata P. Palle, Muthukaman Nagarajan, Rajkumar Shirumalla, Gurpreet Kaur Aulakh, Abhijit Ray
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Publication number: 20100016400Abstract: The present invention generally relates to muscarinic receptor antagonists, which are useful for treating various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to processes for preparing compounds described herein, pharmaceutical compositions containing the disclosed compounds, and the methods for treating diseases mediated through muscarinic receptors.Type: ApplicationFiled: November 18, 2005Publication date: January 21, 2010Inventors: Naresh Kumar, Mohammad Salman, Kirandeep Kaur, Anita Mehta, Sudershan K. Arora, Anita Chugh
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Publication number: 20090221515Abstract: The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disclosed herein can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and autoimmune diseases such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis or allergic rhinitis. Pharmacological compositions containing the compounds of the present invention and the methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders, using the compounds are also provided.Type: ApplicationFiled: August 31, 2005Publication date: September 3, 2009Inventors: Viswajanani Jitendra Sattigeri, Sudershan K. Arora, Venkata P. Palle, Mohammad Salman, Abhijit Ray, Raj Kumar Shirumalla, Abdul Rehaman Abdul Rauf
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Publication number: 20090075909Abstract: The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds of this invention can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and autoimmune diseases, for example, bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection or psoriasis. The present invention also relates to pharmacological compositions containing these monosaccharide derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection, and other inflammatory and/or auto immune disorders.Type: ApplicationFiled: December 22, 2005Publication date: March 19, 2009Applicant: RANBAXY LABORATORIES LIMITED INC.Inventors: Viswajanani Jitendra Sattigeri, Sudershan K. Arora, Mohammad Salman, Venkata P. Palle, Muthukaman Nagarajan, Rajkumar Shirumalla, Gurpreet Kaur Aulakh, Abhijit Ray
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Publication number: 20090048186Abstract: The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disorder herein can be useful for inhibition and prevention of inflammation and associated pathologies including inflammatory and autoimmune diseases such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis and allergic rhinitis. Pharmacological compositions containing compounds disclosed herein and the methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders, using the compounds are also provided.Type: ApplicationFiled: April 19, 2005Publication date: February 19, 2009Inventors: Vishwajanani Jitendra Sattigeri, Sudershan K. Arora, Mohammad Salman, Venkata P. Palle, Ashis Mukherjee, Abhijit Ray, Raj Kumar Shirumalla
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Patent number: 7037899Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-?-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-?-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: GrantFiled: July 1, 2003Date of Patent: May 2, 2006Inventors: Sudershan K Arora, Nawal Kishore, Jang Bahadur Gupta, Vishwas D Joshi
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Patent number: 7005422Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-?-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-?-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: GrantFiled: July 1, 2003Date of Patent: February 28, 2006Assignee: Ranbaxy Laboratories LimitedInventors: Sudershan K Arora, Jang Bahadur Gupta, Vishwas D Joshi
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Patent number: 7005516Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-?-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-?-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: GrantFiled: July 1, 2003Date of Patent: February 28, 2006Assignee: Ranbaxy Laboratories LimitedInventors: Sudershan K Arora, Nawal Kishore
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Patent number: 6956040Abstract: The present invention relates to certain substituted phenyl piperazinyl oxazolidinones, for example, to those having the structure of Formula I with the variables as defined within, and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.Type: GrantFiled: January 17, 2002Date of Patent: October 18, 2005Assignee: Ranbaxy Laboratories LimitedInventors: Anita Mehta, Sudershan K. Arora, Bis{umlaut over (w)}ajit Das, Abhijit Ray, Sonali Rudra, Ashok Rattan
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Publication number: 20040029820Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: ApplicationFiled: July 1, 2003Publication date: February 12, 2004Inventors: Sudershan K. Arora, Nawal Kishore
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Publication number: 20040023900Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: ApplicationFiled: July 1, 2003Publication date: February 5, 2004Inventors: Sudershan K. Arora, Jang Bahadur Gupta, Vishwas D. Joshi
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Publication number: 20040019191Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: ApplicationFiled: July 1, 2003Publication date: January 29, 2004Inventors: Sudershan K. Arora, Nawal Kishore, Jang Bahadur Gupta, Vishwas D. Joshi
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Publication number: 20040018995Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: ApplicationFiled: July 1, 2003Publication date: January 29, 2004Inventors: Sudershan K. Arora, Jang Bahadur Gupta, Vishwas D. Joshi
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Patent number: 6670363Abstract: The present invention relates to the derivatives of specially substituted azole compounds which have improved antifungal activity as compared to known compounds such as fluconazole and itraconazole and the processes for the preparation thereof. This invention also relates to pharmaceutical compositions containing the compounds of the present invention and their use in treating and/or preventing fungal infections in mammals, preferably humans.Type: GrantFiled: May 22, 2000Date of Patent: December 30, 2003Assignee: Ranbaxy Laboratories LimitedInventors: Ashwani Kumar Verma, Sudershan K. Arora, Jasbir Singh Arora, Ashok Rattan
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Patent number: 6590085Abstract: This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-O-isopropylidene-&agr;-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.Type: GrantFiled: March 25, 1999Date of Patent: July 8, 2003Assignee: Ranbaxy Laboratories LimitedInventors: Sudershan K Arora, Nawal Kishore, Jang Bahadur Gupta, Vishwas D Joshi
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Publication number: 20030119817Abstract: The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.Type: ApplicationFiled: January 17, 2002Publication date: June 26, 2003Inventors: Anita Mehta, Sudershan K. Arora, Biswajit Das, Abhijit Ray, Sonali Rudra, Ashok Rattan
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Publication number: 20020103186Abstract: The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effec number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.Type: ApplicationFiled: July 16, 2001Publication date: August 1, 2002Inventors: Anita Mehta, Sudershan K. Arora, Biswajit Das, Abhijit Ray, Sonali Rudra, Ashok Rattan
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Patent number: 6329344Abstract: The present application relates to a group of novel substituted pentose and hexose monosaccharide derivatives, not previously disclosed, which exhibit potent anti-cell adhesion and anti-inflammatory activities. Methods of preparation, pharmaceutical compositions containing the compounds and methods of treatment, suppression and prevention of cell adhesion mediated chronic inflammatory disorders are also described.Type: GrantFiled: October 1, 1999Date of Patent: December 11, 2001Assignee: Ranbaxy Laboratories LimitedInventors: Sudershan K. Arora, Madan P. Tanwar, Jang P. Gupta, Geeta Sharma
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Patent number: 5637570Abstract: Novel dlsubstituted and trisubstituted derivatives of 2,3:4,6-di-O-isopropylidene-.alpha.-L-xylo-2-hexulofuranosonic acid containing at least one alkyl group at position 1, position 4 being occupied by OH, O-alkylamino or O-alkylaminoheterocyclic moiety, and the OH group at position 6 being replaced by a saturated heterocyclic moiety or aminoalkyl heterocyclic group. These compounds exhibit anti-cancer, anti-inflammatory and/or anti-proliferative activities. Methods of preparation, pharmaceutical compositions containing the compounds and methods of treating cancer, inflammatory and/or autoimmune disorders employing the compounds are described.Type: GrantFiled: May 9, 1995Date of Patent: June 10, 1997Assignee: Chemora PharmochemInventors: Sudershan K. Arora, Manoj K. Gupta, Pushappam Lukos, Ravinder Kumar, Shanti N. Sawhney
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Patent number: 5367062Abstract: Derivatives of disubstituted and deoxydisubstituted .alpha.-D-lyxofuranosides and intermediates for preparing these derivatives are described. These compounds exhibit significant antiinflammatory and anti-proliferative activity and are useful for treating inflammatory and/or autoimmune disorders such as psoriasis, asthma, atopic dermatitis, rheumatoid arthritis, osteoarthritis, scleroderma, systemic lupus erythematosus, and cancer (particularly melanoma and colon cancer).Type: GrantFiled: August 21, 1992Date of Patent: November 22, 1994Assignee: Medicarb Inc.Inventors: Sudershan K. Arora, Peter J. Schied