Patents by Inventor Sudeshna SENGUPTA

Sudeshna SENGUPTA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for direct quantification of nucleic acids in real time qPCR
    Patent number: 11603561
    Abstract: A method for direct quantification of nucleic acids in real time qPCR. The invention discloses a method for specific quantification of nucleic acids in real time qPCR. The disclosed invention can be achieved in three ways; 1) using a modified primer for qPCR quantification; 2) using strand displacement based probes for qPCR quantification; 3) using label-free endonuclease probe for qPCR quantification. The mechanism of quantification is based on the fact that, DNA, RNA or modified oligonucleotide based light-up dye-aptamer system, where dye is not fluorescent in free state but its fluorescence increases multi-fold when it binds to its specific aptamer.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: March 14, 2023
    Assignee: INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IIT MADRAS)
    Inventors: Guhan Jayaraman, Sudeshna Sengupta, Shivansh Goyal
  • METHOD FOR DIRECT QUANTIFICATION OF NUCLEIC ACIDS IN REAL TIME qPCR
    Publication number: 20200377934
    Abstract: A method for direct quantification of nucleic acids in real time qPCR. The invention discloses a method for specific quantification of nucleic acids in real time qPCR. The disclosed invention can be achieved in three ways; 1) using a modified primer for qPCR quantification; 2) using strand displacement based probes for qPCR quantification; 3) using label-free endonuclease probe for qPCR quantification. The mechanism of quantification is based on the fact that, DNA, RNA or modified oligonucleotide based light-up dye-aptamer system, where dye is not fluorescent in free state but its fluorescence increases multi-fold when it binds to its specific aptamer.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 3, 2020
    Applicant: INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IIT MADRAS)
    Inventors: Guhan JAYARAMAN, Sudeshna SENGUPTA, Shivansh GOYAL