Patents by Inventor Sudha Veeraraghavan

Sudha Veeraraghavan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant proline-and-arginine rich peptides and methods for using the same
    Patent number: 8030446
    Abstract: The present invention relates to mutant proline-and-arginine rich (PR) peptides with defined structural characteristics for use in inhibiting mammalian 20S proteasome activity and modulating expression of genes regulating the NF-?B pathway. Mutant PR peptides of the present invention differ from wild-type PR peptides by having at least one to three amino acid substitutions, wherein at least one of the amino acid residues at position one, two or three of the mutant PR peptide is positively charged.
    Type: Grant
    Filed: February 12, 2007
    Date of Patent: October 4, 2011
    Assignees: Trustees of Dartmouth College, Board of Regents University of Texas System
    Inventors: Sudha Veeraraghavan, Michael Simons
  • Mutant proline-and-arginine rich peptides and methods for using the same
    Publication number: 20090068736
    Abstract: The present invention relates to mutant proline-and-arginine rich (PR) peptides with defined structural characteristics for use in inhibiting mammalian 20S proteasome activity and modulating expression of genes regulating the NF-?B pathway. Mutant PR peptides of the present invention differ from wild-type PR peptides by having at least one to three amino acid substitutions, wherein at least one of the amino acid residues at position one, two or three of the mutant PR peptide is positively charged.
    Type: Application
    Filed: February 12, 2007
    Publication date: March 12, 2009
    Inventors: Sudha Veeraraghavan, Michael Simons