Patents by Inventor Sudhakar Kambhampati

Sudhakar Kambhampati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of s-fluoromethyl 6?,9?-difluoro-11?-hydroxy-16?-methyl-17?-propionyloxy-3-oxoandrosta-1,4-diene-17?-carbothioate
    Patent number: 7208613
    Abstract: The present invention provides a convenient process for the preparation of S-fluoromethyl 6?,9?-difluoro-11?-hydroxy-16?-methyl-17?-propionyloxy-3-oxoandrosta-1,4-diene-17?-carbothioate, a compound of formula 1, comprising (a) treating 17?-[(N,N-dimethylcarbamoyl)thio]carbonyl-6?,9?-difluoro-11?-hydroxy-16?-methyl-17?-propionyloxy-3-oxoandrosta-1,4-diene, a compound of formula 3 with alkali metal carbonate-alcohol system to obtain 6?,9?-difluoro-11?-hydroxy-16?-methyl-17?-propionyloxy-3-oxoandrosta-1,4-diene-17?-carbothioic acid, a compound of formula 4; (b) reacting the compound of formula 4 with bromofluoromethane to yield the compound of formula 1.
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: April 24, 2007
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Kanaksinh Jesingbhai Jadav, Sudhakar Kambhampati, Trinadha Rao Chitturi, Rajamannar Thennati
  • Convenient synthesis of s-fluoromethyl 6alpha, 9alpha-difluoro-11beta-hydroxy-16alpha-methyl-17alpha-propionyloxy-3-oxoandrosta-1,4-diene-17beta-carbothioate
    Publication number: 20050256325
    Abstract: The present invention provides a convenient process for the preparation of S-fluoromethyl 6?,9?-difluoro-11?-hydroxy-16?-methyl-17?-propionyloxy-3-oxoandrosta-1,4-diene-17?-carbothioate, a compound of formula 1, comprising (a) treating 17?-[(N,N-dimethylcarbamoyl)thio]carbonyl-6?,9?-difluoro-11?-hydroxy-16?-methyl-17?-propionyloxy-3-oxoandrosta-1,4-diene, a compound of formula 3 with alkali metal carbonate-alcohol system to obtain 6?,9?-difluoro-11?-hydroxy-16?-methyl-17?-propionyloxy-3-oxoandrosta-1,4-diene-17?-carbothioic acid, a compound of formula 4; (b) reacting the compound of formula 4 with bromofluoromethane to yield the compound of formula 1.
    Type: Application
    Filed: June 16, 2003
    Publication date: November 17, 2005
    Applicant: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Kanaksinh Jadav, Sudhakar Kambhampati, Trinadha Chitturi, Rajamannar Thennati