Abstract: The present disclosure relates to a method for managing performance of at least one instrumentation device deployed across one or more sites. The method comprises receiving instrument data from the at least one instrumentation device. The instrument data comprises data pertaining to performance of the at least one instrumentation device. The method further comprises validating the instrument data based on at least one of predefined range parameters, predefined error parameters, predefined policy parameters, and historical analysis parameters. The method further comprises determining at least one of calibration issues, maintenance issues, reliability of at least one of the instrumentation device, and quality of the instrument data based on validation of the instrument data and generating performance report based on the validation and the determination for managing the performance of the one or more instrumentation devices.