Patents by Inventor Sudhir Brahmbhatt

Sudhir Brahmbhatt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8850833
    Abstract: An integrated industrial plant includes various systems, all of which use a cryogenic liquid obtained from a common source. One system includes a fermentation unit, in which cold air, chilled by heat exchange with the cryogenic liquid, absorbs excess heat generated by the fermentation. Another system is a lyophilization unit, in which a refrigeration step is performed through the use of air that has been chilled by heat exchange with the cryogenic liquid. Another system is a device for freezing discrete samples of biological products, the samples being frozen by partial immersion in the cryogenic liquid. The invention substantially reduces the use of electric power, and provides systems which operate economically and reliably.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: October 7, 2014
    Assignee: American Air Liquide, Inc.
    Inventor: Sudhir Brahmbhatt
  • Patent number: 7718405
    Abstract: A fermentation process uses substantially pure oxygen as the sole gas introduced into a fermentation vessel while fermentation reactions are active. The oxygen is introduced at multiple locations along the height of the vessel, and is preferably introduced in the vicinity of the blades of an impeller. The invention enhances the rate at which oxygen can be transferred to the fermentation medium, and is especially useful for fermentation media which become very viscous as the process continues. The invention can be used in the manufacture of viscous products such as xanthan gum, or other products having viscosities greater than about 100 cp.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: May 18, 2010
    Assignee: American Air Liquide, Inc.
    Inventor: Sudhir Brahmbhatt
  • Publication number: 20070087402
    Abstract: A fermentation process uses substantially pure oxygen. The oxygen is the only reactive gas which is injected into a fermentation vessel. The oxygen is moved through the vessel solely by its own pressure. The process can be used with both mechanically-agitated and air-lifted fermenters. The mechanically-agitated fermenter includes an analyzer for measuring oxygen concentration in the exhaust line, and adjusting the flow of fresh oxygen into the vessel accordingly. In the air-lifted fermenter, an analyzer measures the oxygen concentration in the head space of the vessel, and operates valves which either recycle the gas from the head space, or vent that gas to the outside, according to the measured concentration. A stream of nitrogen is periodically injected into the vessel to drive out carbon dioxide and other gases, to control the pH of the fermentation medium. The present invention substantially improves the efficiency of a commercial fermentation process.
    Type: Application
    Filed: October 25, 2006
    Publication date: April 19, 2007
    Inventor: Sudhir Brahmbhatt
  • Publication number: 20070065927
    Abstract: A fermentation process uses substantially pure oxygen as the sole gas introduced into a fermentation vessel while fermentation reactions are active. The oxygen is introduced at multiple locations along the height of the vessel, and is preferably introduced in the vicinity of the blades of an impeller. The invention enhances the rate at which oxygen can be transferred to the fermentation medium, and is especially useful for fermentation media which become very viscous as the process continues. The invention can be used in the manufacture of viscous products such as xanthan gum, or other products having viscosities greater than about 100 cp.
    Type: Application
    Filed: September 8, 2006
    Publication date: March 22, 2007
    Inventor: Sudhir Brahmbhatt
  • Publication number: 20060277926
    Abstract: An integrated industrial plant includes various systems, all of which use a cryogenic liquid obtained from a common source. One system includes a fermentation unit, in which cold air, chilled by heat exchange with the cryogenic liquid, absorbs excess heat generated by the fermentation. Another system is a lyophilization unit, in which a refrigeration step is performed through the use of air that has been chilled by heat exchange with the cryogenic liquid. Another system is a device for freezing discrete samples of biological products, the samples being frozen by partial immersion in the cryogenic liquid. The invention substantially reduces the use of electric power, and provides systems which operate economically and reliably.
    Type: Application
    Filed: March 30, 2006
    Publication date: December 14, 2006
    Inventor: Sudhir Brahmbhatt
  • Publication number: 20060277927
    Abstract: An integrated industrial plant includes various systems, all of which use a cryogenic liquid obtained from a common source. One system includes a fermentation unit, in which cold air, chilled by heat exchange with the cryogenic liquid, absorbs excess heat generated by the fermentation. Another system is a lyophilization unit, in which a refrigeration step is performed through the use of air that has been chilled by heat exchange with the cryogenic liquid. Another system is a device for freezing discrete samples of biological products, the samples being frozen by partial immersion in the cryogenic liquid. The invention substantially reduces the use of electric power, and provides systems which operate economically and reliably.
    Type: Application
    Filed: March 30, 2006
    Publication date: December 14, 2006
    Inventor: Sudhir Brahmbhatt
  • Publication number: 20060281171
    Abstract: An integrated industrial plant includes various systems, all of which use a cryogenic liquid obtained from a common source. One system includes a fermentation unit, in which cold air, chilled by heat exchange with the cryogenic liquid, absorbs excess heat generated by the fermentation. Another system is a lyophilization unit, in which a refrigeration step is performed through the use of air that has been chilled by heat exchange with the cryogenic liquid. Another system is a device for freezing discrete samples of biological products, the samples being frozen by partial immersion in the cryogenic liquid. The invention substantially reduces the use of electric power, and provides systems which operate economically and reliably.
    Type: Application
    Filed: March 30, 2006
    Publication date: December 14, 2006
    Inventor: Sudhir Brahmbhatt
  • Publication number: 20060275858
    Abstract: Methods and systems are provided for controlling the addition of oxygen in fermentations to achieve a desired oxygen consumption and substrate yield in fermentation cell cultures. In one aspect, the invention provides a method for regulating the addition of oxygen (O2) to a fermentor during a fermentation process, comprising measuring real-time dissolved oxygen (DO) in a fermentation broth, measuring real-time O2 concentration in the fermentor exhaust, and providing the real-time DO measurement and real-time O2 measurement to an adaptive controller configured to regulate O2 flow into the fermentor responsive to the real-time DO measurement and real-time O2 measurement.
    Type: Application
    Filed: May 30, 2006
    Publication date: December 7, 2006
    Inventors: Victor Saucedo, Sudhir Brahmbhatt
  • Publication number: 20060137523
    Abstract: A system and method for removal of solvents, or other materials, from an exhaust stream, uses an active adsorption bed and a bed that is periodically regenerated. Electrically heated nitrogen may be used to regenerate the beds. A portion of the exhaust stream to be cleaned is diverted to a heat exchanger, so as to pre-heat the nitrogen used for regeneration. Liquid nitrogen, preferably from the same source as that used to provide gas for regeneration, is directed to the active bed, lowering its temperature and increasing its efficiency. The invention avoids the need for the use of steam to heat the nitrogen, and provides a system that is more efficient than those known in the prior art.
    Type: Application
    Filed: December 27, 2004
    Publication date: June 29, 2006
    Inventor: Sudhir Brahmbhatt
  • Publication number: 20050181499
    Abstract: A fermentation process uses substantially pure oxygen. The oxygen is the only reactive gas which is injected into a fermentation vessel. The oxygen is moved through the vessel solely by its own pressure. The process can be used with both mechanically-agitated and air-lifted fermenters. The mechanically-agitated fermenter includes an analyzer for measuring oxygen concentration in the exhaust line, and adjusting the flow of fresh oxygen into the vessel accordingly. In the air-lifted fermenter, an analyzer measures the oxygen concentration in the head space of the vessel, and operates valves which either recycle the gas from the head space, or vent that gas to the outside, according to the measured concentration. A stream of nitrogen is periodically injected into the vessel to drive out carbon dioxide and other gases, to control the pH of the fermentation medium. The present invention substantially improves the efficiency of a commercial fermentation process.
    Type: Application
    Filed: February 17, 2004
    Publication date: August 18, 2005
    Inventor: Sudhir Brahmbhatt