Patents by Inventor Sudhir CHOWDHRY

Sudhir CHOWDHRY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230272485
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Application
    Filed: February 15, 2023
    Publication date: August 31, 2023
    Inventors: Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Zachary D. HORNBY, Sudhir CHOWDHRY, Kristen TURNER, Deepti WILKINSON, Shailaja KASIBHATLA
  • Publication number: 20230248728
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Application
    Filed: March 24, 2023
    Publication date: August 10, 2023
    Inventors: Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Jason CHRISTIANSEN, Zachary D. HORNBY, Sudhir CHOWDHRY, Anthony CELESTE, Kristen TURNER, Deepti WILKINSON
  • Patent number: 11642345
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: May 9, 2023
    Assignee: BOUNDLESS BIO, INC.
    Inventors: Christian Hassig, Ryan Hansen, Snezana Milutinovic, Jason Christiansen, Zachary Hornby, Sudhir Chowdhry, Anthony Celeste, Kristen Turner, Deepti Wilkinson
  • Publication number: 20230078903
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Application
    Filed: October 21, 2022
    Publication date: March 16, 2023
    Inventors: Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Jason CHRISTIANSEN, Zachary HORNBY, Sudhir CHOWDHRY, Anthony CELESTE, Kristen TURNER, Deepti WILKINSON
  • Patent number: 11547711
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Grant
    Filed: January 4, 2022
    Date of Patent: January 10, 2023
    Assignee: BOUNDLESS BIO, INC.
    Inventors: Christian Hassig, Ryan Hansen, Snezana Milutinovic, Jason Christiansen, Zachary Hornby, Sudhir Chowdhry, Anthony Celeste, Kristen Turner, Deepti Wilkinson
  • Publication number: 20220143022
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Application
    Filed: January 4, 2022
    Publication date: May 12, 2022
    Inventors: Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Jason CHRISTIANSEN, Zachary HORNBY, Sudhir CHOWDHRY, Anthony CELESTE, Kristen TURNER, Deepti WILKINSON
  • Publication number: 20220133706
    Abstract: There are provided, inter alia, methods for treatment of cancer. The methods include means of identifying the NAD biosynthetic pathway on which depend cancer cells in a tumor, in a subject suffering from cancer. The methods further include administering to a subject in need a therapeutically effective amount of an inhibitor of the NMRK1 enzyme pathway to a tumor where the cancer cells are dependent of the NAD salvage pathway, allowing to lower the of dose FK866 administered to the subject. The methods also include administering to a subject in need a therapeutically effective amount of a bacterial inhibitor of NADSYN1 to a tumor where the cancer cells depend on the Preiss Handler pathway.
    Type: Application
    Filed: March 13, 2020
    Publication date: May 5, 2022
    Inventors: Paul S. MISCHEL, Bing REN, Vineet BAFNA, Sudhir CHOWDHRY