Patents by Inventor Sudhir Sinha

Sudhir Sinha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050112592
    Abstract: A family of PCR assays is disclosed for determining, both qualitatively and quantitatively, presence of material from a predetermined species source and for quantifying the amount of such material. The assays are based respectively on SINEs uniquely characteristic of pig species, cow species, chicken species, and ruminant sub-order, and having a high copy number. The assays disclosed permit rapid, inexpensive evaluation of meat samples to facilitate elimination from their diet of pork or beef by persons desiring to avoid such food sources; as well as the assay of cattle feed to determine presence therein of ruminant-source proteins, which are a potential source of bovine spongiform encephalopathy (BSE), commonly referred to as “mad cow disease.” The assays amplify the predetermined unique SINEs and the resulting amplified mixture is then evaluated qualitatively by electrophoresis on gel containing ethidium bromide or quantitatively by SYBR Green-based detection or TaqMan chemistry.
    Type: Application
    Filed: December 17, 2003
    Publication date: May 26, 2005
    Inventors: Sudhir Sinha, Jaiprakash Shewale, Jerilyn Walker, Mark Batzer
  • Publication number: 20050069902
    Abstract: An assay for determining presence of human DNA in a sample in which non-human DNA may also be present and for quantitating such human DNA. One embodiment uses intra-Alu based PCR and another uses inter-Alu based PCR. The assays are performed without unique, expensive equipment. The assays are based on detection of multiple-copy Alu elements recently integrated into the human genome that are largely absent from non-human primates and other mammals.
    Type: Application
    Filed: September 30, 2003
    Publication date: March 31, 2005
    Inventors: Sudhir Sinha, Jerilyn Walker, Mark Batzer
  • Publication number: 20050069903
    Abstract: A method for determining gender from a human DNA sample. The loci of Alu element insertion is selected, amplified and evaluated in terms of size of the fragment. The gender assay utilizes AluSTX? for the X chromosome, AluSTY? for the Y chromosome, or both AluSTX? and AluSTY?, to reduce the possibility of error to a negligible quantity. The inserted chromosome yields a large fragment when the homologous region is amplified. The males are distinguished as having two DNA amplicons present, while females have only a single amplicon. The kit adapted for carrying out the method includes a pair of primers to amplifiy the locus and optionally polymerase chain reaction regents.
    Type: Application
    Filed: September 30, 2003
    Publication date: March 31, 2005
    Inventors: Sudhir Sinha, Dale Hedges, Mark Batzer