Abstract: The present invention relates to a method for improving proliferative property of a CMP or a myeloid progenitor cell, including a step of forcibly expressing a MYC family gene and BMI1 gene in any cell in the process of differentiation from a hematopoietic progenitor cell into a myeloid progenitor cell, wherein the myeloid progenitor cell is a progenitor cell of macrophage, dendritic cell, granulocyte, erythroblast, or erythrocyte.

Abstract: A device may receive and process client data, with a first machine learning model, to determine current state data identifying a current state of a client. The device may process the current state data and prior client data, with a second machine learning model, to determine a problem statement for the client and future state data of the client. The device may utilize the second machine learning model to identify initiatives for the client, and costs of the initiatives, based on the problem statement, the current state data, and the future state data, and to assign benefits and priorities to the initiatives. The device may process the initiatives, the benefits and priorities of the initiatives, and the costs of the initiatives, with the second machine learning model, to generate an initiative plan for solving a problem of the problem statement, and may perform actions based on the initiative plan.