Patents by Inventor Sue S. Cross

Sue S. Cross has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5204367
    Abstract: Novel terpene hydroquinones have been isolated from the marine sponge Strongylophora hartmanii. These compounds have been found to have antiviral and anti-leukemia activity. Thus, these compounds, and derivatives thereof, can be used to treat human and animal leukemia as well as viral infections. Additionally, the subject invention concerns the discovery that the terpene hydroquinone known as aureol has strong antiviral activity.
    Type: Grant
    Filed: December 5, 1991
    Date of Patent: April 20, 1993
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Amy E. Wright, Sue S. Cross, Neal S. Burres, Frank Koehn
  • Patent number: 5091412
    Abstract: Novel terpene hydroquinones have been isolated from the marine sponge Stronglophora hartmanii. These compounds have been found to have antiviral activity. Thus, these compounds, and derivatives thereof, can be used to treat viral infections. Additionally, the subject invention concerns the discovery that the terpene hydroquinone known as aureol has strong antiviral activity.
    Type: Grant
    Filed: July 6, 1990
    Date of Patent: February 25, 1992
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Amy S. Wright, Sue S. Cross, Neal S. Burres, Frank Koehn
  • Patent number: 5091368
    Abstract: Novel bioactive compounds have been isolated from blue-green alga. These compounds have been found to have antitumor, antiviral, and immunomodulatory properties. Thus, these compounds, and derivatives thereof, can be used to treat human and animal tumors, inhibit viral growth, and provide immunomodulatory activity.
    Type: Grant
    Filed: August 8, 1990
    Date of Patent: February 25, 1992
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Frank Koehn, Sue S. Cross, Ross E. Longley
  • Patent number: 5079239
    Abstract: Novel sterol disulfates have been isolated from the marine sponge Petrosia weinbergii. These compounds, and derivatives thereof, are useful antiviral compounds. One of these compounds is active against the AIDS virus and exhibits immunosuppressive activity.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: January 7, 1992
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: H. Howard Sun, Sue S. Cross, Frank Koehn, Malika Gunasekera
  • Patent number: 5051519
    Abstract: Novel terpene hydroquinones have been isolated from the marine sponge Strongylophora hartmanii. These compounds have been found to have antiviral and antitumor activity. Thus, these compounds, and derivatives thereof, can be used to treat human and animal tumors as well as viral infections. Additionally, the subject invention concerns the discovery that the terpene hydroquinone known as aureol has strong antiviral activity.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: September 24, 1991
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Amy E. Wright, Sue S. Cross, Neal Burres, Frank Koehn
  • Patent number: 4935439
    Abstract: This invention relates to antiviral organic compositions and derivatives thereof; a process of producing the antiviral compositions; and a method for inhibiting viruses utilizing the compositions. More particularly, the compositions are derived from marine sponges of the genus Epipolasis.
    Type: Grant
    Filed: August 31, 1987
    Date of Patent: June 19, 1990
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Yoel Kashman, Shulamit Hirsch, Sue S. Cross, Frank Koehn
  • Patent number: 4866084
    Abstract: A new class of novel, biologically active bisindole alkaloid compounds, which have been named topsentins, pharmaceutical compositions containing them, methods of producing the compounds and methods of using them are disclosed. This new class of compounds has the generic formula: ##STR1## R.sup.1-8 are the same or different selected from --H, --OH, halogen, --R, --OR, --OCOR, or --OA;Y is the single group --O, or two groups, same or different, selected from --H, --OH, --OR, or --OCOR with the provision that Y shall not be two --OH groups;Z are the same or different selected from --H, --R;R is C1-5 alkyl and A is --R--phenyl.The compounds are antiviral agents and antitumor agents which are effective against specific tumors.
    Type: Grant
    Filed: December 19, 1988
    Date of Patent: September 12, 1989
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Sarath P. Gunasekera, Sue S. Cross, Yoel Kashman, May S. Lui, Kenneth L. Rinehart, Shinji Tsujii
  • Patent number: 4808590
    Abstract: This invention relates to novel compositions which are useful as antitumor, antiviral and antifungal compositions, a process of producing the compositions and a method for inhibiting tumors, viruses and fungi utilizing the composition. More particularly, the novel compositions are derived from marine sponge Theonella sp.
    Type: Grant
    Filed: July 15, 1988
    Date of Patent: February 28, 1989
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Tatsuo Higa, Shinichi Sakemi, Sue S. Cross
  • Patent number: 4801606
    Abstract: This invention relates to novel compositions which are useful as antitumor, antiviral and antifungal compositions, a process of producing the compositions and a method for inhibiting tumors, viruses and fungi utilizing the composition. More particularly, the novel compositions are derived from marine sponge Theonella sp.
    Type: Grant
    Filed: July 17, 1987
    Date of Patent: January 31, 1989
    Assignee: Harbor Branch Oceanographic Institution Inc.
    Inventors: Tatsuo Higa, Shinichi Sakemi, Sue S. Cross
  • Patent number: 4801607
    Abstract: This invention relates to antitumor and antiviral furanoditerpenoid compositions, a process of producing the compositions and a method for inhibiting tumors and viruses utilizing the compositions. More particularly, the new compositions are antitumor and antiviral furanoterpenoids which are derived from marine organisms, i.e., the marine sponge Spongia sp.
    Type: Grant
    Filed: March 25, 1987
    Date of Patent: January 31, 1989
    Assignee: Harbor Branch Oceanographic Institution, Inc.
    Inventors: Shigeo Komoto, Oliver J. McConnell, Sue S. Cross