Abstract: An enteric medicinal composition comprising a drug ingredient, pectin, alginic acid, or a derivative thereof, and water is provided that is easy to swallow.

Abstract: An objective of the present invention is to provide an anti-inflammatory analgesic for external use comprising etodolac as NSAID. The anti-inflammatory analgesic for external use is excellent not only in skin permeability but also in penetratability and diffusivity into tissues present in portions deeper than the skin, can act directly on the muscles or joint tissues with inflammation or pain, and is a little irritant to the skin. The anti-inflammatory analgesic for external use of the present invention is characterized by comprising etodolac and a local anesthetic.

Abstract: Mast cell degranulation inhibitors having a carboxyl group have not been developed as external preparations due to the low transdermal permeability thereof. By formulating external preparations thereof, side effects on the internal organs by oral administration can be avoided. Some of the mast cell degranulation inhibitors show drastically inferior photostability, which is also one cause of suppressed development of the drug as an external preparation. The present invention aims at improving the transdermal permeability and photostability of mast cell degranulation inhibitors by forming a salt of the mast cell degranulation inhibitor with an organic amine. Consequently, an external preparation of a mast cell degranulation inhibitor can be provided and the photostability of the mast cell degranulation inhibitor itself, and a preparation containing same can be improved.

Abstract: It is an object of the present invention to provide an external preparation having enhanced transdermal penetration of a mast cell degranulation inhibitor. It is also an object of the present invention to provide a method for improving the photostability of a preparation containing a mast cell degranulation inhibitor. The present invention provides an external preparation containing a mast cell degranulation inhibitor and a topical anesthetic. Further, the method for enhancing the photostability of a preparation containing a mast cell degranulation inhibitor according to the present invention includes adding a topical anesthetic thereto.

Abstract: An object of the present invention is to provide a composition having both of enteric property and dosing property that a conventional composition has not had. The present invention, which can achieve the above object, relates to an enteric medicinal composition, comprising a drug ingredient, pectin, alginic acid or derivative thereof, and water. According to the present invention, it becomes easier to take an enteric composition which has been conventionally difficult to be swallowed.

Abstract: It is an object of the present invention to provide an external preparation having enhanced transdermal penetration of a mast cell degranulation inhibitor. It is also an object of the present invention to provide a method for improving the photostability of a preparation containing a mast cell degranulation inhibitor. The present invention provides an external preparation containing a mast cell degranulation inhibitor and a topical anesthetic. Further, the method for enhancing the photostability of a preparation containing a mast cell degranulation inhibitor according to the present invention includes adding a topical anesthetic thereto.

Abstract: An objective of the present invention is to provide an anti-inflammatory analgesic for external use comprising etodolac as NSAID. The anti-inflammatory analgesic for external use is excellent not only in skin permeability but also in penetratability and diffusivity into tissues present in portions deeper than the skin, can act directly on the muscles or joint tissues with inflammation or pain, and is a little irritant to the skin. The anti-inflammatory analgesic for external use of the present invention is characterized by comprising etodolac and a local anesthetic.