Patents by Inventor Suezanne Parker

Suezanne Parker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating cancer using interferon-?-expressing polynucleotides
    Patent number: 7470675
    Abstract: The present invention provides a pharmaceutical composition, comprising a non-infectious, non-integrating polynucleotide construct comprising a polynucleotide encoding an interferon ? and one or more cationic compounds. The present invention also provides methods of treating cancer in a mammal, comprising administering into a tissue of the mammal a non-infectious, non-integrating polynucleotide construct comprising a polynucleotide encoding a cytokine. In addition, the present invention also relates to the methodology for selective transfection of malignant cells with polynucleotides expressing therapeutic or prophylactic molecules in intra-cavity tumor bearing mammals. More specifically, the present invention provides a methodology for the suppression of an intra-cavity dissemination of malignant cells, such as intraperitoneal dissemination.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: December 30, 2008
    Assignee: Vical Incorporated
    Inventors: Holly Horton, Suezanne Parker, Marston Manthorpe, Philip L. Felgner, Jukka Hartikka
  • Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
    Publication number: 20070225243
    Abstract: The present invention provides a pharmaceutical composition, comprising a non-infectious, non-integrating polynucleotide construct comprising a polynucleotide encoding an interferon ? and one or more cationic compounds. The present invention also provides methods of treating cancer in a mammal, comprising administering into a tissue of the mammal a non-infectious, non-integrating polynucleotide construct comprising a polynucleotide encoding a cytokine. In addition, the present invention also relates to the methodology for selective transfection of malignant cells with polynucleotides expressing therapeutic or prophylactic molecules in intra-cavity tumor bearing mammals. More specifically, the present invention provides a methodology for the suppression of an intra-cavity dissemination of malignant cells, such as intraperitoneal dissemination.
    Type: Application
    Filed: February 23, 2007
    Publication date: September 27, 2007
    Inventors: Holly Horton, Suezanne Parker, Marston Manthorpe, Philip Felgner, Jukka Hartikka
  • Methods for treating cancer using cytokine-expressing polynucleotides
    Patent number: 7268120
    Abstract: The present invention provides a pharmaceutical composition, comprising a non-infectious, non-integrating polynucleotide construct comprising a polynucleotide encoding an interferon ? and one or more cationic compounds. The present invention also provides methods of treating cancer in a mammal, comprising administering into a muscle of the mammal a non-infectious, non-integrating DNA polynucleotide construct comprising a polynucleotide encoding a cytokine. In addition, the present invention also relates to the methodology for selective transfection of malignant cells with polynucleotides expressing therapeutic or prophylactic molecules in intra-cavity tumor bearing mammals. More specifically, the present invention provides a methodology for the suppression of an intra-cavity dissemination of malignant cells, such as intraperitoneal dissemination.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: September 11, 2007
    Assignee: Vical Incorporated
    Inventors: Holly Horton, Suezanne Parker, Marston Manthorpe, Philip L. Felgner, Jukka Hartikka
  • Plasmids suitable for IL-2 expression
    Publication number: 20050065107
    Abstract: The present invention relates to plasmids suitable for IL-2 expression, particularly, human IL-2 expression, and related methods.
    Type: Application
    Filed: October 15, 2004
    Publication date: March 24, 2005
    Inventors: Peter Hobart, Michal Margalith, Suezanne Parker, Shirin Khatibi