Patents by Inventor Sufan Chien

Sufan Chien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Direct cellular energy delivery system
    Patent number: 9066866
    Abstract: A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein is provided. The vesicle can further comprise a biomolecule, such as for example ATP. Methods of using the vesicle for delivery of biomolecules are also provided.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: June 30, 2015
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: William D. Ehringer, Sufan Chien
  • DIRECT CELLULAR ENERGY DELIVERY SYSTEM
    Publication number: 20110311442
    Abstract: A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein is provided. The vesicle can further comprise a biomolecule, such as for example ATP. Methods of using the vesicle for delivery of biomolecules are also provided.
    Type: Application
    Filed: June 17, 2011
    Publication date: December 22, 2011
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: William D. Ehringer, Sufan Chien
  • Direct cellular energy delivery system
    Publication number: 20060193905
    Abstract: A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein is provided. The vesicle can further comprise a biomolecule, such as for example ATP. Methods of using the vesicle for delivery of biomolecules are also provided.
    Type: Application
    Filed: February 7, 2006
    Publication date: August 31, 2006
    Inventors: William Ehringer, Sufan Chien
  • Direct cellular energy delivery system
    Patent number: 7056529
    Abstract: A vesicle comprises ATP and a phospholipid which is a stable vesicle former. The vesicle has a fusion rate of at least 20 vesicle fusions/second.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: June 6, 2006
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: William D. Ehringer, Sufan Chien
  • Wound healing compositions and methods of use
    Patent number: 7041312
    Abstract: A wound-healing composition comprises a wound-treating component and vesicles. The vesicles comprise a phospholipid which is a stable vesicle former and ATP.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: May 9, 2006
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: William D. Ehringer, Sufan Chien
  • Wound healing compositions and methods of use
    Publication number: 20040137051
    Abstract: A wound-healing composition comprises a wound-treating component and vesicles. The vesicles comprise a phospholipid which is a stable vesicle former and ATP.
    Type: Application
    Filed: July 25, 2003
    Publication date: July 15, 2004
    Inventors: William D. Ehringer, Sufan Chien
  • Direct cellular energy delivery system
    Publication number: 20030235611
    Abstract: A vesicle comprises ATP and a phospholipid which is a stable vesicle former. The vesicle has a fusion rate of at least 20 vesicle fusions/second.
    Type: Application
    Filed: March 25, 2003
    Publication date: December 25, 2003
    Inventors: William D. Ehringer, Sufan Chien
  • Method for employing the delta opioid dadle to extend tissue survival time during ischemia
    Patent number: 5656420
    Abstract: This invention concerns a method for extending the survival time of mammalian lung tissue subjected to ischemia, by which said tissue is perfused with a preservation solution comprising a therapeutic dose of the delta opioid DADLE ([D-Ala.sup.2,D-Leu.sup.5 ]-Enkephalin) under hypothermic conditions.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: August 12, 1997
    Assignee: University Of Kentucky Research Foundation
    Inventor: Sufan Chien