Patents by Inventor Sufeng Ma

Sufeng Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 2-{3-[3-amino-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-1-(isopropylsulfonyl)azetidin-3-yl}acetonitrile
    Patent number: 12686681
    Abstract: The present application relates to a preparation method for a pyrrolopyrimidine compound, comprising: obtaining a compound 3 from a compound 2, obtaining a compound 4P2 from the compound 3, and obtaining a pyrrolopyrimidine compound of formula I by removing a protecting group from the compound 4P2. The preparation method of the present application has the advantages of simple operation, mild reaction conditions and high yield, avoids the problems of low yield and a large amount of impurities and difficult separation of same in original routes, reduces production costs, and is suitable for industrial production. Furthermore, the product yield of each step is high, and basically reaches about 80%, and even the yield of some steps can reach 90% or more.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: July 21, 2026
    Assignee: PrimeGene (Beijing) Co., Ltd.
    Inventors: Sufeng Ma, Junru Han, Jin Wang, Wei Hu, Li Zhu
  • POLYMORPH OF JAK TYROSINE KINASE INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20250163055
    Abstract: The present disclosure relates to a polymorph of a compound 2-{3-[3-amino-4-(7H-pyrrolo[2, 3-d]pyrimidine-4-yl-1H-pyrazole-1-yl]-1-(isopropylsulfonyl)azetidine-3-yl}acetonitrile (formula A), and a pharmaceutical composition and a use thereof.
    Type: Application
    Filed: February 24, 2023
    Publication date: May 22, 2025
    Applicant: Prime Gene Therapeutics Co., Ltd.
    Inventors: Sufeng Ma, Huasong Luo, Junru Han, Wei Hu, Li Zhu
  • PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND
    Publication number: 20230303578
    Abstract: The present application relates to a preparation method for a pyrrolopyrimidine compound, comprising: obtaining a compound 3 from a compound 2, obtaining a compound 4P2 from the compound 3, and obtaining a pyrrolopyrimidine compound of formula I by removing a protecting group from the compound 4P2. The preparation method of the present application has the advantages of simple operation, mild reaction conditions and high yield, avoids the problems of low yield and a large amount of impurities and difficult separation of same in original routes, reduces production costs, and is suitable for industrial production. Furthermore, the product yield of each step is high, and basically reaches about 80%, and even the yield of some steps can reach 90% or more.
    Type: Application
    Filed: August 25, 2021
    Publication date: September 28, 2023
    Applicant: PrimeGene (Beijing) Co., Ltd.
    Inventors: Sufeng Ma, Junru Han, Jin Wang, Wei Hu, Li Zhu