Patents by Inventor Sug Hyung Lee

Sug Hyung Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL DEATH DOMAIN PROTEINS
    Publication number: 20110201780
    Abstract: In accordance with the present invention, there are provided novel Death Domain (DD), Death Effector Domain (DED) and NB-ARC domain proteins. The invention also provides nucleic acid molecules encoding DD, DED and NB-ARC domain proteins, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention DDs, DEDs or NB-ARC domains. Such DDs, DEDs and NB-ARC domains and/or anti-DD, anti-DED or anti-NB-ARC domain antibodies are useful for discovery of drugs that suppress infection, autoimmunity, inflammation, allergy, allograft rejection, sepsis, and other diseases.
    Type: Application
    Filed: March 17, 2011
    Publication date: August 18, 2011
    Applicant: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
    Inventors: John C. Reed, Adam Godzik, Krzysztof Pawlowski, Loredana Fiorentino, Sug Hyung Lee, Wilfried Roth, Frank Stenner-Liewen
  • CARD DOMAIN CONTAINING POLYPEPTIDES, ENCODING NUCLEIC ACIDS, AND METHODS OF USE
    Publication number: 20110008319
    Abstract: The invention provides caspase recruitment domain (CARD)-containing polypeptides, CARD, NB-ARC, ANGIO-R, LRR and SAM domains therefrom, as well as encoding nucleic acid molecules and specific antibodies. The invention also provides related screening, diagnostic and therapeutic methods.
    Type: Application
    Filed: November 30, 2009
    Publication date: January 13, 2011
    Applicant: Burnham Institute for Medical Research
    Inventors: John C. Reed, Frederick F. Pio, Adam Godzik, Christian Stehlik, Jason S. Damiano, Sug Hyung Lee, Vasco A. Oliveira, Hideki Hayashi, Kryzysztof Pawlowski
  • Card domain containing polypeptides, encoding nucleic acids, and methods of use
    Patent number: 7626001
    Abstract: The invention provides caspase recruitment domain (CARD)-containing polypeptides, CARD, NB-ARC, ANGIO-R, LRR and SAM domains therefrom, as well as encoding nucleic acid molecules and specific antibodies. The invention also provides related screening, diagnostic and therapeutic methods.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: December 1, 2009
    Assignee: Burnham Institute for Medical Research
    Inventors: John C. Reed, Frederick F. Pio, Adam Godzik, Christian Stehlik, Jason S. Damiano, Sug Hyung Lee, Vasco A. Oliveira, Hideki Hayashi, Kryzysztof Pawlowski
  • NOVEL DEATH DOMAIN PROTEINS
    Publication number: 20090011501
    Abstract: In accordance with the present invention, there are provided novel Death Domain (DD), Death Effector Domain (DED) and NB-ARC domain proteins. The invention also provides nucleic acid molecules encoding DD, DED and NB-ARC domain proteins, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention DDs, DEDs or NB-ARC domains. Such DDs, DEDs and NB-ARC domains and/or anti-DD, anti-DED or anti-NB-ARC domain antibodies are useful for discovery of drugs that suppress infection, autoimmunity, inflammation, allergy, allograft rejection, sepsis, and other diseases.
    Type: Application
    Filed: June 5, 2008
    Publication date: January 8, 2009
    Applicant: THE BURNHAM INSTITUTE
    Inventors: John C. Reed, Adam Godzik, Krzysztof Pawlowski, Loredana Fiorentino, Sug Hyung Lee, Wilfried Roth, Frank Stenner-Liewen
  • Card domain containing polypeptides, encoding nucleic acids, and methods of use
    Patent number: 7196182
    Abstract: The invention provides caspase recruitment domain (CARD)-containing polypeptides, CARD, NB-ARC, ANGIO-R, LRR and SAM domains therefrom, as well as encoding nucleic acid molecules and specific antibodies. The invention also provides related screening, diagnostic and therapeutic methods.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: March 27, 2007
    Assignee: The Burnham Institute
    Inventors: John C. Reed, Frederick F. Pio, Adam Godzik, Christian Stehlik, Jason S. Damiano, Sug Hyung Lee, Vasco A. Oliveira, Hideki Hayashi, Krzysztof Pawlowski
  • Death domain proteins
    Patent number: 6965023
    Abstract: In accordance with the present invention, there are provided novel Death Domain (DD), Death Effector Domain (DED) and NB-ARC domain proteins. The invention also provides nucleic acid molecules encoding DD, DED and NB-ARC domain proteins, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention DDs, DEDs or NB-ARC domains. Such DDs, DEDs and NB-ARC domains and/or anti-DD, anti-DED or anti-NB-ARC domain antibodies are useful for discovery of drugs that suppress infection, autoimmunity, inflammation, allergy, allograft rejection, sepsis, and other diseases.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: November 15, 2005
    Assignee: The Burnham Institute
    Inventors: John C. Reed, Adam Godzik, Krzysztof Pawlowski, Loredana Fiorentino, Sug Hyung Lee, Wilfried Roth, Frank Stenner-Liewen
  • Novel death domain proteins
    Publication number: 20030049702
    Abstract: In accordance with the present invention, there are provided novel Death Domain (DD), Death Effector Domain (DED) and NB-ARC domain proteins. The invention also provides nucleic acid molecules encoding DD, DED and NB-ARC domain proteins, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention DDs, DEDs or NB-ARC domains. Such DDs, DEDs and NB-ARC domains and/or anti-DD, anti-DED or anti-NB-ARC domain antibodies are useful for discovery of drugs that suppress infection, autoimmunity, inflammation, allergy, allograft rejection, sepsis, and other diseases.
    Type: Application
    Filed: November 15, 2001
    Publication date: March 13, 2003
    Inventors: John C. Reed, Adam Godzik, Krzysztof Pawlowski, Loredana Fiorentino, Sug Hyung Lee, Wilfried Roth, Frank Stenner-Liewen
  • Card domain containing polypeptides, encoding nucleic acids, and methods of use
    Publication number: 20020176853
    Abstract: The invention provides caspase recruitment domain (CARD)-containing polypeptides, CARD, NB-ARC, ANGIO-R, LRR and SAM domains therefrom, as well as encoding nucleic acid molecules and specific antibodies. The invention also provides related screening, diagnostic and therapeutic methods.
    Type: Application
    Filed: May 23, 2001
    Publication date: November 28, 2002
    Inventors: John C. Reed, Frederick F. Pio, Adam Godzik, Christian Stehlik, Jason S. Damiano, Sug Hyung Lee, Vasco A. Oliveira, Hideki Hayashi, Krzysztof Pawlowski