Patents by Inventor Suguru Takeo

Suguru Takeo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing polysaccharide ron substance with a synthetase
    Patent number: 5565342
    Abstract: A polysaccharide RON substance which has antitumor activity can be produced by fermenting sucrose with a synthetase. The synthetase can be isolated from Leuconostoc strains. Preferred strains of the microorganism are Leuconostoc mesenteroides FERM BP-2242, 2711, 2712, 2713, 2714, and 2670. The substance exhibits antitumor activity against syngenic tumor Meth A, a transplantable tumor in mice.
    Type: Grant
    Filed: September 15, 1993
    Date of Patent: October 15, 1996
    Assignee: Sapporo Breweries Limited
    Inventors: Yasuo Yoneta, Hisao Kado, Suguru Takeo, Yutaka Mitani, Nobuhiro Watanabe
  • Method for producing biologically active polysaccharide RON substance
    Patent number: 5332667
    Abstract: A biologically active polysaccharide RON substance which is excellent in such biological activities as antitumor activities, is produced by using a microorganism belonging to the genus Leuconostoc, which has an activity of producing the RON substance.
    Type: Grant
    Filed: September 2, 1993
    Date of Patent: July 26, 1994
    Assignee: Sapporo Breweries Limited
    Inventors: Hisao Kado, Yasuo Yoneta, Suguru Takeo, Yutaka Mitani, Nobuhiro Watanabe
  • HP530 compounds and process for preparing the same
    Patent number: 5168100
    Abstract: Disclosed are novel HP530 compounds, their derivatives or their pharmaceutically permissible salts, a process for preparing them and an antitumor substances containing them as active ingredient. The HP530 compounds and their derivatives expressed by the general formula below can be prepared by cultivating Streptomyces sp. HP530 (FERM BP-2786) or and chemically derivation. ##STR1## where X is a C.sub.2 -C.sub.4 acyl group or a hydrogen atom, Y is a C.sub.2 -C.sub.4 acyl group or a hydrogen atom and Z is a group expressed by the formula (II), (III) or (IV).
    Type: Grant
    Filed: March 12, 1991
    Date of Patent: December 1, 1992
    Assignee: Sapporo Breweries Limited
    Inventors: Naoki Abe, Nobuyasu Enoki, Yasukazu Nakakita, Hideaki Uchida, Ryoichi Sato, Suguru Takeo, Nobuhiro Watanabe
  • Polysaccharide RDP substance
    Patent number: 4764507
    Abstract: A polysaccharide RDP substance having the ultraviolet absorption spectrum depicted in FIG. 1, the infrared absorption spectrum depicted in FIG. 2 and the .sup.13 C-NMR spectrum depicted in FIG. 3 is obtained from rice bran by extraction.
    Type: Grant
    Filed: March 5, 1984
    Date of Patent: August 16, 1988
    Assignees: Sapparo Breweries Limited, Daicel Chemical Industries, Ltd., Etsuo Ito
    Inventors: Suguru Takeo, Hisao Kado, Nobuhiro Watanabe, Kiichi Uchida, Yoshitada Mori
  • Polysaccharide RON substance
    Patent number: 4762825
    Abstract: A polysaccharide RON substance having the ultraviolet absorption spectrum depicted in FIG. 1, the infrared absorption spectrum depicted in FIG. 2 and the .sup.13 C-NMR spectrum depicted in FIG. 3 is obtained from rice bran by extraction and purification; and pharmacological composition containing said RON substance.
    Type: Grant
    Filed: August 12, 1985
    Date of Patent: August 9, 1988
    Assignees: Sapporo Breweries Limited, Daicel Chemical Industries, Ltd., Etsuo Ito
    Inventors: Suguru Takeo, Hisao Yamamoto, Hisao Kado, Nobuhiro Watanabe, Minoru Kamimura, Kiichi Uchida, Yoshitada Mori