Patents by Inventor Suhani D. Vora

Suhani D. Vora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230304001
    Abstract: The present disclosure provides methods and compositions of modulating expression of a target nucleic acid sequence in a cell. The method comprises introducing into the cell a nucleic acid sequence encoding a Cas9 fusion protein and a guide RNA, wherein the Cas9 fusion protein and the guide RNA are expressed and co-localize at a target site and modulate the expression of the target nucleic acid sequence.
    Type: Application
    Filed: April 25, 2023
    Publication date: September 28, 2023
    Inventors: Suhani D. Vora, Alejandro Chavez, Jing Cheng, Benjamin W. Pruitt
  • Patent number: 11674138
    Abstract: The present disclosure provides methods and compositions of modulating expression of a target nucleic acid sequence in a cell. The method comprises introducing into the cell a nucleic acid sequence encoding a Cas9 fusion protein and a guide RNA, wherein the Cas9 fusion protein and the guide RNA are expressed and co-localize at a target site and modulate the expression of the target nucleic acid sequence.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: June 13, 2023
    Assignee: President and Fellows of Harvard College
    Inventors: Suhani D. Vora, Alejandro Chavez, Jing Cheng, Benjamin W. Pruitt
  • Publication number: 20190376060
    Abstract: The present disclosure provides methods and compositions of modulating expression of a target nucleic acid sequence in a cell. The method comprises introducing into the cell a nucleic acid sequence encoding a Cas9 fusion protein and a guide RNA, wherein the Cas9 fusion protein and the guide RNA are expressed and co-localize at a target site and modulate the expression of the target nucleic acid sequence.
    Type: Application
    Filed: March 13, 2018
    Publication date: December 12, 2019
    Applicant: President and Fellows of Harvard College
    Inventors: Suhani D. Vora, Alejandro Chavez, Jing Cheng, Benjamin W. Pruitt