Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules as defined within Formula I (as defined herein) which function as inhibitors of glucose-regulated protein 78 (GRP78) within cancer cells and/or immune cells, and which function as effective therapeutic agents for treating, ameliorating, and preventing various forms of cancer (e.g., pancreatic cancer), viral infections (e.g. SARS-CoV-2), and inflammatory diseases. In addition, this invention also relates to a new class of PROTACs having Formulas II, III and IV (as defined herein) which function as degraders of GRP78 within cancer and/or immune cells. Pharmaceutical compositions comprising said compounds of Formulas I, II, III, or IV are also within the scope of the present invention.

Abstract: A method for recognizing product detection missed is performed by an electronic device. The method includes: obtaining a surveillance video collected by a surveillance device on a product production line; generating product detection results by inputting video frames of the surveillance video into a product detection model; generating detecting action recognition results by inputting the video frames of the surveillance video into an action recognition model; and determining whether product detection is missed based on the product detection results and the detecting action recognition results.