Patents by Inventor Suja HIRIYANNA

Suja HIRIYANNA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RP2 and RPGR vectors for treating X-linked retinitis pigmentosa
    Patent number: 11617801
    Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: April 4, 2023
    Assignee: The United States of America,as represented by the Secretary, Department of Health and Human Services
    Inventors: Zhijian Wu, Anand Swaroop, Suja Hiriyanna, Tiansen Li
  • Methods and compositions for treating Leber congenital amaurosis
    Patent number: 11421219
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Grant
    Filed: May 28, 2019
    Date of Patent: August 23, 2022
    Assignee: THE USA, AS REPRESENTED BY THE SECRETARY, DHHS
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna
  • RP2 AND RPGR VECTORS FOR TREATING X-LINKED RETINITIS PIGMENTOSA
    Publication number: 20200289670
    Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
    Type: Application
    Filed: April 21, 2020
    Publication date: September 17, 2020
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Zhijian Wu, Anand Swaroop, Suja Hiriyanna, Tiansen Li
  • RP2 and RPGR vectors for treating X-linked retinitis pigmentosa
    Patent number: 10646588
    Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: May 12, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna
  • METHODS AND COMPOSITIONS FOR TREATING LEBER CONGENITAL AMAUROSIS
    Publication number: 20200024593
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Application
    Filed: May 28, 2019
    Publication date: January 23, 2020
    Inventors: Zhijian WU, Anand SWAROOP, Suddhasil MOOKHERJEE, Suja HIRIYANNA
  • Methods and compositions for treating leber congenital amaurosis
    Patent number: 10351844
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: July 16, 2019
    Assignee: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna
  • RP2 AND RPGR VECTORS FOR TREATING X-LINKED RETINITIS PIGMENTOSA
    Publication number: 20180043035
    Abstract: Disclosed are adeno-associated virus (AAV) vectors comprising a nucleotide sequence encoding RP2 or RPGR-ORF15 and related pharmaceutical compositions. Also disclosed are methods of treating or preventing X-linked retinitis pigmentosa, increasing photoreceptor number in a retina of a mammal, and increasing visual acuity of a mammal using the vectors and pharmaceutical compositions.
    Type: Application
    Filed: March 11, 2016
    Publication date: February 15, 2018
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Zhijian Wu, Anand Swaroop, Suddhasil Mookherjee, Suja Hiriyanna, Tiansen Li
  • METHODS AND COMPOSITIONS FOR TREATING LEBER CONGENITAL AMAUROSIS
    Publication number: 20170275615
    Abstract: Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.
    Type: Application
    Filed: August 27, 2015
    Publication date: September 28, 2017
    Inventors: Zhijian WU, Anand SWAROOP, Suddhasil MOOKHERJEE, Suja HIRIYANNA