Patents by Inventor Sujata Iyer
Sujata Iyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12115532Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge contains an internal gap with at least one hydrophobic surface for enabling an electrowetting induced movement of a microfluidic droplet that has magnetic beads and further has a bead accumulation zone, into which the microfluidic droplet is transferable by electrowetting force and the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap has a bead extraction opening adjacent to the bead accumulation zone. The bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet.Type: GrantFiled: April 25, 2023Date of Patent: October 15, 2024Assignee: TECAN TRADING AGInventors: Patrick Kinney, Sujata Iyer, Tin Ngo, Jennifer Ji, Marta Matvienko, Tiffany Ding (Lay)
-
Patent number: 11992833Abstract: A pipette tip extension attachable to a pipette tip having a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall has an outer side and an inner side and forms at the proximal end a reception aperture for inserting a pipette tip, and at the distal end a dispense aperture. The pipette tip extension further has an inner cavity, a distance element connected to the inner side of the exterior wall, and a constriction element.Type: GrantFiled: December 20, 2019Date of Patent: May 28, 2024Assignee: TECAN TRADING AGInventors: Adrian Sager, Philipp Ott, Patrick Kinney, Hagen Reinhardt, Michael Keller, Sujata Iyer
-
Publication number: 20240118239Abstract: A cartridge for use in an electrowetting sample processing system, the cartridge having one or more inlet ports for introducing an input liquid into an internal gap of the cartridge, which has at least one hydrophobic surface for enabling an electrowetting induced movement of multiple microfluidic droplets separated from the input liquid. The cartridge further has at least one outlet port that is operably connected to the inlet port for providing a liquid flow through the cartridge, if a liquid driving force, in particular an electrowetting force or a pressure force, is applied to at least a part of the input liquid.Type: ApplicationFiled: December 15, 2023Publication date: April 11, 2024Inventors: Patrick Kinney, Sujata Iyer, Daniel Hoffmeyer, Manjeet Dhindsa, Tin Ngo, Tiffany Ding (Lay), Torleif Ove Björnson
-
Patent number: 11951482Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge has a liquid input port for introducing an input liquid into an internal gap of the cartridge, the input liquid providing for at least one droplet, directly or via a liquid separation process within the internal gap, and the internal gap having at least one hydrophobic surface, at least one processing zone for processing samples located in the processing zone, and a delivery zone for delivering the at least one droplet from the liquid input port to the at least one processing zone. The delivery zone is configured to provide a repeating pattern of interacting electrowetting force for simultaneously transporting the at least one droplet within the delivery zone.Type: GrantFiled: December 22, 2021Date of Patent: April 9, 2024Assignee: TECAN TRADING AGInventors: Patrick Kinney, Tiffany Ding (Lay), Manjeet Dhindsa, Daniel Tran, Jennifer Ji, Sujata Iyer, Tin Ngo
-
Patent number: 11933760Abstract: A cartridge for use in an electrowetting sample processing system, the cartridge having at least one inlet port for introducing an input liquid in an internal gap of the cartridge, wherein the gap has at least one hydrophobic surface and is configured to provide an electrowetting induced movement of a microfluidic droplet of input liquid, wherein the input liquid has a carrier liquid and a processing liquid and the gap has a capture zone that is configured to capture at least a part of the processing liquid as a microfluidic droplet by use of electrowetting force and the gap further has a transfer zone that is configured to provide a passage for the carrier liquid next to the microfluidic droplet, while processing liquid is captured in the capture zone.Type: GrantFiled: September 1, 2022Date of Patent: March 19, 2024Assignee: TECAN TRADING AGInventors: Patrick Kinney, Tin Ngo, Sujata Iyer, Daniel Hoffmeyer, Manjeet Dhindsa, Tiffany Ding (Lay)
-
Publication number: 20230256444Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge contains an internal gap with at least one hydrophobic surface for enabling an electrowetting induced movement of a microfluidic droplet that has magnetic beads and further has a bead accumulation zone, into which the microfluidic droplet is transferable by electrowetting force and the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap has a bead extraction opening adjacent to the bead accumulation zone. The bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet.Type: ApplicationFiled: April 25, 2023Publication date: August 17, 2023Inventors: Patrick Kinney, Sujata Iyer, Tin Ngo, Jennifer Ji, Marta Matvienko, Tiffany Ding (Lay)
-
Patent number: 11666914Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge contains an internal gap with at least one hydrophobic surface for enabling an electrowetting induced movement of a microfluidic droplet that has magnetic beads and further has a bead accumulation zone, into which the microfluidic droplet is transferable by electrowetting force and the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap has a bead extraction opening adjacent to the bead accumulation zone. The bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet.Type: GrantFiled: May 9, 2018Date of Patent: June 6, 2023Assignee: TECAN TRADING AGInventors: Patrick Kinney, Sujata Iyer, Tin Ngo, Jennifer Ji, Marta Matvienko, Tiffany Ding (Lay)
-
Publication number: 20230003685Abstract: A cartridge for use in an electrowetting sample processing system, the cartridge having at least one inlet port for introducing an input liquid in an internal gap of the cartridge, wherein the gap has at least one hydrophobic surface and is configured to provide an electrowetting induced movement of a microfluidic droplet of input liquid, wherein the input liquid has a carrier liquid and a processing liquid and the gap has a capture zone that is configured to capture at least a part of the processing liquid as a microfluidic droplet by use of electrowetting force and the gap further has a transfer zone that is configured to provide a passage for the carrier liquid next to the microfluidic droplet, while processing liquid is captured in the capture zone.Type: ApplicationFiled: September 1, 2022Publication date: January 5, 2023Applicant: TECAN TRADING AGInventors: Patrick KINNEY, Tin Ngo, Sujata Iyer, Daniel Hoffmeyer, Manjeet Dhindsa, Tiffany Ding (Lay)
-
Publication number: 20220111388Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge has a liquid input port for introducing an input liquid into an internal gap of the cartridge, the input liquid providing for at least one droplet, directly or via a liquid separation process within the internal gap, and the internal gap having at least one hydrophobic surface, at least one processing zone for processing samples located in the processing zone, and a delivery zone for delivering the at least one droplet from the liquid input port to the at least one processing zone. The delivery zone is configured to provide a repeating pattern of interacting electrowetting force for simultaneously transporting the at least one droplet within the delivery zone.Type: ApplicationFiled: December 22, 2021Publication date: April 14, 2022Applicant: TECAN TRADING AGInventors: Patrick Kinney, Tiffany Ding (Lay), Manjeet Dhindsa, Daniel Tran, Jennifer Ji, Sujata Iyer, Tin Ngo
-
Publication number: 20220023853Abstract: A method of treating an isolated area of a sample with a liquid is disclosed. The method has the steps of generating an isolated area of a sample by a first fluid reservoir where the first fluid reservoir enclosing a distal end of a second fluid reservoir and the isolated area of the sample being sealed towards the remaining area of the sample, bringing the isolated area of the sample into fluid connection with the second fluid reservoir, dispensing a fluid from the second fluid reservoir into the first fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a first direction, and aspirating the fluid from the first fluid reservoir into the second fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a second direction.Type: ApplicationFiled: December 20, 2018Publication date: January 27, 2022Applicant: TECAN TRADING AGInventors: Patrick KINNEY, Sujata IYER, Philipp OTT, Adrian SAGER
-
Publication number: 20220023854Abstract: A pipette tip extension attachable to a pipette tip having a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall has an outer side and an inner side and forms at the proximal end a reception aperture for inserting a pipette tip, and at the distal end a dispense aperture. The pipette tip extension further has an inner cavity, a distance element connected to the inner side of the exterior wall, and a constriction element.Type: ApplicationFiled: December 20, 2019Publication date: January 27, 2022Applicant: TECAN TRADING AGInventors: Adrian SAGER, Philipp OTT, Patrick KINNEY, Hagen REINHARDT, Michael KELLER, Sujata IYER
-
Publication number: 20220001376Abstract: A pipette tip extension having a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall has an outer side and an inner side and encloses an inner cavity which is delimited by the inner side of the exterior wall. The exterior wall forms at the proximal end a reception aperture. The pipette tip extension further has one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity.Type: ApplicationFiled: December 20, 2018Publication date: January 6, 2022Applicant: Tecan Trading AGInventors: Patrick KINNEY, Sujata IYER, Philipp OTT, Adrian SAGER
-
Patent number: 10739248Abstract: Methods and systems are disclosed for controlling a particle analyzer based at least in part on a generated entrainment factor for a sample. The features include flowing a sample with a series of particles through the particle analyzer, detecting events and calculating an expected frequency of those events based on a distribution, such as a Poisson distribution, and measuring an observed frequency of particle events. An entrainment factor may be generated from a ratio of observed event frequency to expected event frequency. Further adjustment to the particle analyzer maybe performed based on the indicated entrainment factor such as adjusted sorting bias.Type: GrantFiled: November 2, 2018Date of Patent: August 11, 2020Assignee: BECTON, DICKINSON AND COMPANYInventors: Joseph Trotter, Sujata Iyer
-
Publication number: 20190344272Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge contains an internal gap with at least one hydrophobic surface for enabling an electrowetting induced movement of a microfluidic droplet that has magnetic beads and further has a bead accumulation zone, into which the microfluidic droplet is transferable by electrowetting force and the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap has a bead extraction opening adjacent to the bead accumulation zone. The bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet.Type: ApplicationFiled: May 9, 2018Publication date: November 14, 2019Applicant: TECAN TRADING AGInventors: Patrick Kinney, Sujata Iyer, Tin Ngo, Jennifer Ji, Marta Matvienko, Tiffany Ding (Lay)
-
Publication number: 20190331638Abstract: A cartridge for use in an electrowetting sample processing system, the cartridge having one or more inlet ports for introducing an input liquid into an internal gap of the cartridge, which has at least one hydrophobic surface for enabling an electrowetting induced movement of multiple microfluidic droplets separated from the input liquid. The cartridge further has at least one outlet port that is operably connected to the inlet port for providing a liquid flow through the cartridge, if a liquid driving force, in particular an electrowetting force or a pressure force, is applied to at least a part of the input liquid.Type: ApplicationFiled: April 25, 2018Publication date: October 31, 2019Applicant: TECAN TRADING AGInventors: Patrick Kinney, Sujata Iyer, Daniel Hoffmeyer, Manjeet Dhindsa, Tin Ngo, Tiffany Ding (Lay), Torleif Ove Bjornson
-
Publication number: 20190331639Abstract: A cartridge for use in an electrowetting sample processing system, the cartridge having at least one inlet port for introducing an input liquid in an internal gap of the cartridge, wherein the gap has at least one hydrophobic surface and is configured to provide an electrowetting induced movement of a microfluidic droplet of input liquid, wherein the input liquid has a carrier liquid and a processing liquid and the gap has a capture zone that is configured to capture at least a part of the processing liquid as a microfluidic droplet by use of electrowetting force and the gap further has a transfer zone that is configured to provide a passage for the carrier liquid next to the microfluidic droplet, while processing liquid is captured in the capture zone.Type: ApplicationFiled: April 25, 2018Publication date: October 31, 2019Applicant: TECAN TRADING AGInventors: PATRICK KINNEY, Tin Ngo, Sujata Iyer, Daniel Hoffmeyer, Manjeet Dhindsa, Tiffany Ding (Lay)
-
Publication number: 20190329258Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge has a liquid input port for introducing an input liquid into an internal gap of the cartridge, the input liquid providing for at least one droplet, directly or via a liquid separation process within the internal gap, and the internal gap having at least one hydrophobic surface, at least one processing zone for processing samples located in the processing zone, and a delivery zone for delivering the at least one droplet from the liquid input port to the at least one processing zone. The delivery zone is configured to provide a repeating pattern of interacting electrowetting force for simultaneously transporting the at least one droplet within the delivery zone.Type: ApplicationFiled: April 25, 2018Publication date: October 31, 2019Applicant: TECAN TRADING AGInventors: Patrick Kinney, Tiffany Ding (Lay), Manjeet Dhindsa, Daniel Tran, Jennifer Ji, Sujata Iyer, Tin Ngo
-
Publication number: 20190072478Abstract: Methods and systems are disclosed for controlling a particle analyzer based at least in part on a generated entrainment factor for a sample. The features include flowing a sample with a series of particles through the particle analyzer, detecting events and calculating an expected frequency of those events based on a distribution, such as a Poisson distribution, and measuring an observed frequency of particle events. An entrainment factor may be generated from a ratio of observed event frequency to expected event frequency. Further adjustment to the particle analyzer maybe performed based on the indicated entrainment factor such as adjusted sorting bias.Type: ApplicationFiled: November 2, 2018Publication date: March 7, 2019Inventors: Joseph Trotter, Sujata Iyer
-
Patent number: 10190963Abstract: Methods and systems are disclosed for generating an entrainment factor in a flow cytometry sample. The methods comprise flowing a sample with a series of particles through the flow cytometer, detecting events and calculating an expected frequency of those events based on a distribution, such as a Poisson distribution, and measuring an observed frequency of particle events. An entrainment factor may be generated from a ratio of observed event frequency to expected event frequency. Further adjustment to the flow cytometer maybe performed based on the indicated entrainment factor such as adjusted sorting bias.Type: GrantFiled: January 31, 2014Date of Patent: January 29, 2019Assignee: Becton, Dickinson and CompanyInventors: Joseph Trotter, Sujata Iyer
-
Publication number: 20140216128Abstract: Methods and systems are disclosed for generating an entrainment factor in a flow cytometry sample. The methods comprise flowing a sample with a series of particles through the flow cytometer, detecting events and calculating an expected frequency of those events based on a distribution, such as a Poisson distribution, and measuring an observed frequency of particle events. An entrainment factor may be generated from a ratio of observed event frequency to expected event frequency. Further adjustment to the flow cytometer maybe performed based on the indicated entrainment factor such as adjusted sorting bias.Type: ApplicationFiled: January 31, 2014Publication date: August 7, 2014Applicant: BECTON DICKINSON AND COMPANYInventors: Joseph Trotter, Sujata Iyer