Abstract: Systems or techniques that facilitate hybrid 3D-to-2D slice-wise object localization ensembles are provided. In various embodiments, a system can access at least one three-dimensional voxel array. In various aspects, the system can localize, via execution of a deep learning ensemble, an object depicted in the at least one three-dimensional voxel array. In various instances, the deep learning ensemble can receive as input the at least one three-dimensional voxel array. In various cases, the deep learning ensemble can produce as output a set of two-dimensional object location indicators respectively corresponding to a set of two-dimensional slices of the at least one three-dimensional voxel array.