Patents by Inventor Suji Xie

Suji Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artemisinin analogs having antimalarial, antiproliferative, and antitumor activities and chemoselective methods of making the same
    Patent number: 6586464
    Abstract: Methods for producing novel artemisinin analogs and artemisinin dimers having antimalarial, antiproliferative and antitumor activities are described herein. These novel artemisinin analogs and artemisinin dimers have the following structure or diastereomers thereof, having antimalarial, and antiproliferative and antitumor activities wherein, the monomers of the present invention are formed when n is I and R is alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl or heteroaryl. The dimers of the present invention are formed when n is 2 and R is a linker including, but not limited to, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl or heteroaryl.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: July 1, 2003
    Assignees: Johns Hopkins University, Hauser, Inc.
    Inventors: Gary H. Posner, Hardwin O'Dowd, Suji Xie, Theresa A. Shapiro, Christopher Murray
  • Artemisinin analogs having antimalarial, antiproliferative, and antitumor activities and chemoselective methods of making the same
    Publication number: 20020055528
    Abstract: Methods for producing novel artemisinin analogs and artemisinin dimers having antimalarial, antiproliferative and antitumor activities are described herein.
    Type: Application
    Filed: June 22, 2001
    Publication date: May 9, 2002
    Inventors: Gary H. Posner, Hardwin O'Dowd, Suji Xie, Theresa A. Shapiro, Christopher Murray
  • Artemisinin analogs having antimalarial antiproliferative and antitumor activities and chemoselective methods of making the same
    Patent number: 6297272
    Abstract: Methods for producing novel artemisinin analogs and artemisinin dimers having antimalarial, antiproliferative and antitumor activities are described herein. These novel artemisinin analogs and artemisinin dimers have the following structure or diastereomers thereof, having antimalarial, and antiproliferative and antitumor activities wherein, the monomers of the present invention are formed when n is 1 and R is alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl or heteroaryl. The dimers of the present invention are formed when n is 2 and R is a linker including, but not limited to, alkyl, cycloalkyl, heteroalkyl, heterocycloalkyl, alkenyl, alkynyl, aryl or heteroaryl.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: October 2, 2001
    Assignees: Hauser, Inc., Johns Hopkins University
    Inventors: Gary H. Posner, Hardwin O'Dowd, Suji Xie, Theresa A. Shapiro, Christopher Murray