Patents by Inventor Sujita Sukumaran

Sujita Sukumaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC MOLECULES PROVIDING TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPY
    Publication number: 20230331808
    Abstract: The present invention relates to a chimeric molecule useful in adoptive cell therapy (ACT), and cells comprising the same. The chimeric molecule can act as a modulator of cellular activity enhancing responses when an endogenous T-cell receptor (TCR) is engaged with its cognate antigen. The present invention also provides proteins, nucleic acids encoding the chimeric molecule and therapeutic uses thereof.
    Type: Application
    Filed: May 12, 2023
    Publication date: October 19, 2023
    Inventors: John Bridgeman, Robert Hawkins, Ruben Rodriguez, Sujita Sukumaran, Xingliang Zhou, Eric Gschweng
  • Chimeric molecules providing targeted costimulation for adoptive cell therapy
    Patent number: 11697677
    Abstract: The present invention relates to a chimeric molecule useful in adoptive cell therapy (ACT), and cells comprising the same. The chimeric molecule can act as a modulator of cellular activity enhancing responses when an endogenous T-cell receptor (TCR) is engaged with its cognate antigen. The present invention also provides proteins, nucleic acids encoding the chimeric molecule and therapeutic uses thereof.
    Type: Grant
    Filed: August 25, 2022
    Date of Patent: July 11, 2023
    Assignee: INSTIL BIO (UK) LIMITED
    Inventors: John Bridgeman, Robert Hawkins, Ruben Rodriguez, Sujita Sukumaran, Xingliang Zhou, Eric Gschweng
  • BIPARTITE AND TRIPARTITE SIGNALING IMMUNE CELLS
    Publication number: 20170246278
    Abstract: Embodiments of the disclosure include compositions and methods effective for immunotherapy, such as for cancer. The embodiments include cells that recognize a combination of two signals or three signals present at the tumor microenvironment. In certain embodiments, the signals for antigen stimulation, co-stimulation, and cytokine signaling act through separate molecules, although in certain embodiments the signals for antigen stimulation and co-stimulation are transmitted through the same molecule.
    Type: Application
    Filed: October 19, 2015
    Publication date: August 31, 2017
    Inventors: Juan Fernando Vera Valdes, Ann Marie Leen, Sujita Sukumaran