Abstract: Described herein is a nucleic acid molecule including an asymmetrically modified inverted terminal repeat (ITR). An AAV vector including the nucleic acid molecule has advantages of increased productivity and expression efficiency of a transgene, and decreased genotoxicity, by having an asymmetric ITR in which any one of two ITRs is modified. Also, described herein is are compositions and vectors.

Abstract: A foldable display device may include: a display panel displaying an image; a cover window over the display panel; and a back plate under the display panel. The back plate may include a plate top having a plurality of holes, a plate bottom having at least one groove corresponding to the plurality of holes, and an adhesive layer attaching the plate top and the plate bottom.

Abstract: In the present invention, it was confirmed that the modified protein in which the 356th serine of Runx3 is substituted with alanine has an increased activity of maintaining the complex with Brd2 by more than 10 times compared to the wild-type Runx3, and the apoptosis effect is improved in various cancer cell lines compared to the wild-type Runx3. Therefore, the modified protein in which the 356th serine of Runx3 is substituted with an amino acid that cannot be phosphorylated by a kinase of the present invention, the polynucleotide coding thereof, the vector carrying the polynucleotide, or the virus or cell transformed with the vector can be used as a therapeutic agent for various cancers.

Abstract: The present invention relates to a mold structure for manufacturing a securing film, and in particular, to a mold structure for manufacturing a securing film by alternately stacking and coupling two thin circular plates having different diameters from each other and allowing a concave structure to be formed within a transparent synthetic resin film which is closely adhered to outer circumferential surfaces of the two plates according to a height difference between the outer circumferential surface of the plate having the larger diameter and the outer circumferential surface of the plate having the smaller diameter, and a securing film which is accurately manufactured by filling the concave structure of the transparent synthetic resin film with a colored ink and coating on the resulting outer circumferential surface a transparent synthetic resin film such as a polyethylene terephthalate (PET).