Patents by Inventor Suk-Fong Sin

Suk-Fong Sin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified plants expressing proteinase inhibitors, SaPIN2a or SaPIN2b, and methods of use thereof for the inhibition of trypsin- and chymotrypsin-like activities
    Patent number: 7256327
    Abstract: The present invention relates to proteinase inhibitor II genes, SaPIN2a and SaPIN2b, their production in transformed plants, and isolation of SaPIN2a and SaPIN2b proteins from transformed plants of the invention. The invention further relates to use in inhibiting endogenous protease activities in transformed plants. In specific embodiments, the protease activities are trypsin-like and chymotrypsin-like activities. The invention relates to a method for protection of heterologous protein production in transformed plants by the co-expression of a proteinase inhibitor gene, e.g. SaPIN2a or SaPIN2b, which encodes a proteinase inhibitor protein, or a biologically active fragment, analog, and variant thereof, that inhibits protease activities. Specifically, the present invention also provides methods of inhibiting programmed cell death, including senescence, in plants. The invention further relates to methods to enhance resistance of plants to pests or pathogens, including insects.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: August 14, 2007
    Assignee: The University of Hong Kong
    Inventors: Mee Len Chye, Zeng-Fu Xu, Suk-Fong Sin
  • Genetically modified plants expressing proteinase inhibitors, SaPIN2a or SaPIN2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activities
    Publication number: 20040205846
    Abstract: The present invention relates to proteinase inhibitor II genes, SaPIN2a and SaPIN2b, their production in transformed plants, and isolation of SaPIN2a and SaPIN2b proteins from transformed plants of the invention. The invention further relates to use in inhibiting endogenous protease activities in transformed plants. In specific embodiments, the protease activities are trypsin-like and chymotrypsin-like activities. The invention relates to a method for protection of heterologous protein production in transformed plants by the co-expression of a proteinase inhibitor gene, e.g. SaPIN2a or SaPIN2b, which encodes a proteinase inhibitor protein, or a biologically active fragment, analog, and variant thereof, that inhibits protease activities. Specifically, the present invention also provides methods of inhibiting programmed cell death, including senescence, in plants. The invention further relates to methods to enhance resistance of plants to pests or pathogens, including insects.
    Type: Application
    Filed: December 1, 2003
    Publication date: October 14, 2004
    Inventors: Mee Len Chye, Zeng-Fu Xu, Suk-Fong Sin