Patents by Inventor Suk Kyoon Yoon

Suk Kyoon Yoon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10442796
    Abstract: The present invention relates to a novel 2,3,5-substituted thiophene compound having inhibitory activity against kinases, an anticancer agent including the compound as an active ingredient, and a method for preparing the compound.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: October 15, 2019
    Assignees: Korea Institute of Science and Technology, Daegu-Gyeongbuk Medical Innovation Foundation
    Inventors: Tae Bo Sim, Woo Young Hur, Chi Man Song, Ho Jong Yoon, Seung Hye Choi, Han Na Cho, Hwan Geun Choi, Nam Doo Kim, Jung Beom Son, Eun Hwa Ko, Hyun Kyoung Kim, Joong Heui Cho, Seock Yong Kang, So Young Kim, Yi Kyung Ko, Seung Yeon Lee, Suk Kyoon Yoon, Jae Hyun Bae
  • Publication number: 20190047993
    Abstract: The present invention relates to a novel 2,3,5-substituted thiophene compound having inhibitory activity against kinases, an anticancer agent including the compound as an active ingredient, and a method for preparing the compound.
    Type: Application
    Filed: August 16, 2018
    Publication date: February 14, 2019
    Inventors: Tae Bo Sim, Woo Young Hur, Chi Man Song, Ho Jong Yoon, Seung Hye Choi, Han Na Cho, Hwan Geun Choi, Nam Doo Kim, Jung Beom Son, Eun Hwa Ko, Hyun Kyoung Kim, Joong Heui Cho, Seock Yong Kang, So Young Kim, Yi Kyung Ko, Seung Yeon Lee, Suk Kyoon Yoon, Jae Hyun Bae
  • Publication number: 20100305364
    Abstract: The present invention relates to a new process for preparing diisopropyl {[1-(hydroxymethyl)-cyclopropyl]oxy}methylphosphonate (2), which is a key intermediate for synthesizing an antiviral (particularly, against hepatitis B virus) nucleoside analogue. The present invention also relates to new intermediates, and a process for preparing the antiviral nucleoside analogue from the compound (2) prepared according to the present invention.
    Type: Application
    Filed: August 10, 2010
    Publication date: December 2, 2010
    Inventors: Suk-Kyoon YOON, Kun-Hye Nam, Sang-Who Lee, Won-Kyo Joung, Sang-Chul Choi, Ki-Kon Lee
  • Patent number: 7795463
    Abstract: Disclosed is a process for preparing a compound of the following formula (2): including the steps of reacting a compound of the following formula (4): with trityl chloride to prepare trityloxy-acetic acid ethyl ester of the following formula (8): reacting the compound of formula (8) with ethyl magnesium halide to prepare 1-trityloxymethyl-cyclopropanol of the following formula (9): combining the 1-trityloxymethyl-cyclopropanol of formula (9) with diisopropylbromo-methylphosphonate in a solvent in the presence of a base to prepare (1-trityloxymethyl-cyclopropoxymethyl)-phosphonic acid diisopropyl ester of the following formula (10): as a solid form, and converting the trityl group of the compound of formula (10) into a hydroxyl group.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: September 14, 2010
    Assignee: LG Life Sciences Ltd.
    Inventors: Suk-Kyoon Yoon, Kun-Hye Nam, Sang-Who Lee, Won-Kyo Joung, Sang-Chul Choi, Ki-Kon Lee
  • Publication number: 20090187019
    Abstract: The present invention relates to a new process for preparing diisopropyl {[1-(hydroxymethyl)-cyclopropyl]oxy}methylphosphonate (2), which is a key intermediate for synthesizing an antiviral (particularly, against hepatitis B virus) nucleoside analogue. The present invention also relates to new intermediates, and a process for preparing the antiviral nucleoside analogue from the compound (2) prepared according to the present invention.
    Type: Application
    Filed: June 27, 2005
    Publication date: July 23, 2009
    Applicant: LG LIFE SCIENCE LTD.
    Inventors: Suk-Kyoon Yoon, Kun-Hye Nam, Sang-Who Lee, Won-Kyo Joung, Sang-Chul Choi, Ki-Kon Lee
  • Patent number: 7097967
    Abstract: The present invention provides a method of predicting a food-drug interaction in vivo, in the case of an orally administered drug interactive with digestive enzymes in the gastrointestinal tract, by measuring the activity of the drug to the digestive enzymes in vitro, which is based on the fact that the ingestion of foods causes the absorption of drug in vivo to decrease due to the above interaction between a drug and digestive enzymes. The present invention further provides methods of minimizing the change of absorption in vivo caused by the ingestion of foods by reducing the action of digestive enzymes, for example, introduction of prodrugs, modification of the chemical structure of drug, design of drug formulation, etc.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: August 29, 2006
    Assignee: LG Life Sciences Ltd.
    Inventors: Aeri Kim, Kwan Hyung Cho, Sun Hwa Lee, Suk Kyoon Yoon, Hee Dong Park, Kyung Ha Chung, Ho Jun Kim, Han Joo Maeng, Tae Hun Kim, Bong Chan Kim, Sung Ji Kim
  • Patent number: 7015337
    Abstract: The present invention provides a novel process for preparing a compound represented by the above formula 7, which is an important intermediate for an oral thrombin inhibitor, by one-pot reaction. In accordance with the present invention, the above intermediate for the thrombin inhibitor may be obtained in a high yield.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: March 21, 2006
    Assignee: LG Life Sciences Ltd.
    Inventors: Suk Kyoon Yoon, Bong Chan Kim, Won Hyuk Jung, Jae Chul Lee, Koo Lee, Cheol Won Park
  • Publication number: 20050154229
    Abstract: The present invention relates to a maleic acid salt of (2S)-N-{5-[amino(imino)methyl]-2-thienyl}methyl-1-{(2R)-2-[(carboxymethyl)amino]-3,3-diphenylpropanoyl}-2-pyrrolidinecarboxamide.
    Type: Application
    Filed: March 21, 2003
    Publication date: July 14, 2005
    Inventors: Aeri Kim, Jae-Hyeon Park, Suk-Kyoon Yoon, Cheol-Won Park, Kwan-Hyung Cho
  • Publication number: 20050113309
    Abstract: The present invention relates to crystalline forms of (2S)-N-5-[amino(imino)methyl]-2-thienyl-methyl-1-(2R)-2-[(carboxymethyl)amino]-3,3-diphenylpropanoyl-2-pyrrolidinecarboxamide nH2O.
    Type: Application
    Filed: March 21, 2003
    Publication date: May 26, 2005
    Inventors: Aeri Kim, Jae-Hyeon Park, Suk-Kyoon Yoon, Bong-Chan Kim, Sung-Ji Kim, Kwan-Hyung Cho
  • Publication number: 20040116714
    Abstract: The present invention provides a novel process for preparing a compound represented by the above formula 7, which is an important intermediate for an oral thrombin inhibitor, by one-pot reaction. In accordance with the present invention, the above intermediate for the thrombin inhibitor may be obtained in a high yield.
    Type: Application
    Filed: October 2, 2003
    Publication date: June 17, 2004
    Inventors: Suk Kyoon Yoon, Bong Chan Jung, Won Hyuk Jung, Jae Chul Lee, Koo Lee, Cheol Won Park
  • Publication number: 20040081641
    Abstract: The present invention provides a method of predicting a food-drug interaction in vivo, in the case of an orally administered drug interactive with digestive enzymes in the gastrointestinal tract, by measuring the activity of the drug to the digestive enzymes in vitro, which is based on the fact that the ingestion of foods causes the absorption of drug in vivo to decrease due to the above interaction between a drug and digestive enzymes. The present invention further provides methods of minimizing the change of absorption in vivo caused by the ingestion of foods by reducing the action of digestive enzymes, for example, introduction of prodrugs, modification of the chemical structure of drug, design of drug formulation, etc.
    Type: Application
    Filed: October 24, 2002
    Publication date: April 29, 2004
    Applicant: LG LIFE SCIENCES LTD.
    Inventors: Aeri Kim, Kwan Hyung Cho, Sun Hwa Lee, Suk Kyoon Yoon, Hee Dong Park, Kyung Ha Chung, Ho Jun Kim, Han Joo Maeng, Tae Hun Kim, Bong Chan Kim, Sung Ji Kim