Patents by Inventor Suke Wang
Suke Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7872101Abstract: The invention relates to the use of the interaction between the GPR78 polypeptide or the GPR26 polypeptide and their identified ligands and antagonists as the basis for screening methods for the identification of agents that modulate the activity of these receptors, and for diagnostic and therapeutic purposes. The agents identified by the screening methods of the invention have use in the treatment of GPR78- and/or GPR26-mediated disorders, including, but not limited to, neurological disorders (such as anxiety disorders), metabolic disorders, cardiovascular disorders, hormone-related disorders, vascular disorders and hyperproliferative disorders (such as cancer).Type: GrantFiled: December 3, 2007Date of Patent: January 18, 2011Assignee: Schering CorporationInventors: Suke Wang, Frederick James Monsma, Jr., Xiaoxin Yang, Eric L. Gustafson, Maureen Laverty, Elizabeth B. Smith
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Publication number: 20090176254Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: ApplicationFiled: March 11, 2008Publication date: July 9, 2009Inventors: Marvin Bayne, Tanaz Hashemi, Chaogang He, Suke Wang
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Patent number: 7547523Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.Type: GrantFiled: January 5, 2007Date of Patent: June 16, 2009Assignee: Schering CorporationInventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick James Monsma, Jr., Kelley L. Morse, Shelby P. Umland, Suke Wang
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Publication number: 20090075297Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: ApplicationFiled: August 26, 2008Publication date: March 19, 2009Inventors: MARVIN BAYNE, Tanaz Hashemi, Chaogang He, Suke Wang
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Patent number: 7417122Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: GrantFiled: June 26, 2007Date of Patent: August 26, 2008Assignee: Schering CorporationInventors: Marvin Bayne, Tanaz Hashemi, Chaogang He, Suke Wang
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Publication number: 20070255044Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: ApplicationFiled: June 26, 2007Publication date: November 1, 2007Inventors: Marvin Bayne, Tanaz Hashemi, Chaogang He, Suke Wang
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Patent number: 7250163Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: GrantFiled: September 22, 2004Date of Patent: July 31, 2007Assignee: Schering CorporationInventors: Marvin Bayne, Tanaz Hashemi, Chaogang He, Suke Wang
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Publication number: 20070117155Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.Type: ApplicationFiled: January 5, 2007Publication date: May 24, 2007Inventors: Jiang Behan, Joseph Hedrick, Thomas Laz, Frederick Monsma, Kelley Morse, Shelby Umland, Suke Wang
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Patent number: 7166705Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.Type: GrantFiled: July 8, 2003Date of Patent: January 23, 2007Assignee: Schering CorporationInventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang
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Patent number: 6939953Abstract: The present invention provides an isolated mammalian leukotriene receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by leukotriene. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian leukotriene receptor.Type: GrantFiled: March 22, 2002Date of Patent: September 6, 2005Assignee: Schering CorporationInventors: Suke Wang, Ling Pang, Thomas M. Laz
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Publication number: 20050074768Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.Type: ApplicationFiled: July 8, 2003Publication date: April 7, 2005Inventors: Jiang Behan, Joseph Hedrick, Thomas Laz, Frederick Monsma, Kelley Morse, Shelby Umland, Suke Wang
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Publication number: 20050026213Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: ApplicationFiled: September 22, 2004Publication date: February 3, 2005Inventors: Marvin Bayne, Tanaz Hashemi, Chaogang He, Suke Wang
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Publication number: 20040136984Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: ApplicationFiled: February 13, 2004Publication date: July 15, 2004Inventors: Marvin Bayne, Tanaz Hashemi, Chaogang He, Suke Wang
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Patent number: 6693182Abstract: The present invention provides isolated mammalian GalR3 receptors, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods for making the receptors using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptors and are useful for treating medical conditions caused or mediated by galanin. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian GalR3 receptors.Type: GrantFiled: August 22, 1997Date of Patent: February 17, 2004Assignee: Schering CorporationInventors: Marvin Bayne, Tanaz Hashemi, Chaogang He, Suke Wang
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Patent number: 6613533Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.Type: GrantFiled: March 19, 2001Date of Patent: September 2, 2003Assignee: Schering CorporationInventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang
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Publication number: 20020156241Abstract: The present invention provides an isolated mammalian leukotriene receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by leukotriene. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian leukotriene receptor.Type: ApplicationFiled: March 22, 2002Publication date: October 24, 2002Inventors: Suke Wang, Ling Pang, Thomas M. Laz
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Patent number: 6465212Abstract: The present invention provides an isolated mammalian leukotriene receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by leukotriene. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian leukotriene receptor.Type: GrantFiled: September 20, 1999Date of Patent: October 15, 2002Assignee: Schering CorporationInventors: Suke Wang, Ling Pang, Thomas M. Laz
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Publication number: 20020098539Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.Type: ApplicationFiled: March 19, 2001Publication date: July 25, 2002Inventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang
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Patent number: 6204017Abstract: The present invention provides an isolated mammalian histamine receptor, isolated or recombinant nucleic acids and recombinant vectors encoding the same, host cells comprising the nucleic acids and vectors, and methods of making the receptor using the host cells. This invention further provides antibodies and antigen binding fragments thereof which specifically bind to the receptor and are useful for treating medical conditions caused or mediated by histamine. Also provided are screening methods for identifying specific agonists and antagonists of the mammalian histamine receptor.Type: GrantFiled: October 7, 1999Date of Patent: March 20, 2001Assignee: Schering CorporationInventors: Jiang X. Behan, Joseph A. Hedrick, Thomas M. Laz, Frederick J. Monsma, Kelley L. Morse, Shelby P. Umland, Suke Wang