Patents by Inventor Sukumar Nandi

Sukumar Nandi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of Lorcaserin hydrochloride
    Patent number: 10308611
    Abstract: The present invention provides a process for the preparation of crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia), which comprises, Formula (Ia) (i) providing a solution of Lorcaserin base in a solvent; (ii) if water is present, removing water from the reaction mixture; (iii) adding hydrogen chloride to the reaction mixture; (iv) combining the reaction mixture with a suitable anti-solvent; and (v) isolating the crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia).
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: June 4, 2019
    Assignee: Aurobindo Pharma Ltd
    Inventors: Sukumar Nandi, Akkina Naresh, Syam Prasad Reddy Rao Annareddy, Gona Bala Narsimha Reddy, Meenakshi Sunderam Sivakumaran
  • Process for the preparation of Mirabegron alpha-form crystals
    Patent number: 10253005
    Abstract: The present invention provides a process for the preparation of ?-Form crystals of Mirabegron using a solvent selected from water.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: April 9, 2019
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sukumar Nandi, Shantan Kumar Reddy, Gona Bala Narashimha Reddy, Sivakumaran Meenakshisundaram
  • A process for the preparation of Lorcaserin Hydrochloride
    Publication number: 20180194734
    Abstract: The present invention provides a process for the preparation of crystalline Lorcaserin hydrochloride hemihydrate of Formula (1a), which comprises, Formula (1a) (i) providing a solution of Lorcaserin base in a solvent; (ii) if water is present, removing water from the reaction mixture; (iii) adding hydrogen chloride to the reaction mixture; (iv) combining the reaction mixture with a suitable anti-solvent; and (v) isolating the crystalline Lorcaserin hydrochloride hemihydrate of Formula (1a).
    Type: Application
    Filed: March 18, 2016
    Publication date: July 12, 2018
    Applicant: Aurobindo Pharma Ltd
    Inventors: Sukumar Nandi, Akkina Naresh, Syam Prasad Reddy Rao Annareddy, Gona Bala Narsimha Reddy, Meenakshi Sunderam Sivakumaran
  • A process for the preparation of Mirabegron alpha-Form crystals
    Publication number: 20180194743
    Abstract: The present invention provides a process for the preparation of ?-Form crystals of Mirabegron using a solvent selected from water.
    Type: Application
    Filed: May 9, 2016
    Publication date: July 12, 2018
    Applicant: Aurobindo Pharma Ltd
    Inventors: Sukumar Nandi, Shantan Kumar Reddy, Gona Bala Narashimha Reddy, Sivakumaran Meenakshisundaram
  • Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester
    Patent number: 8846915
    Abstract: The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: September 30, 2014
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Ganagadnar Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the preparation of Dutasteride
    Patent number: 8563728
    Abstract: The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5?-androst-1-en-3-one-17?-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I).
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: October 22, 2013
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Balanarasimha Reddy Gona, Naresh Akkina, Rani Ananta, Islam Aminul, Sivakumaran Meenakshisunderam
  • Process for preparing pyrimidine propenaldehyde
    Patent number: 8394956
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of formula (I), which is an useful intermediate in the preparation of Rosuvastatin.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: March 12, 2013
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhara Bhima Shankar Nangi, Rani Ananta, Sivakumaran Meenakshisunderam
  • Process for preparing rosuvastatin calcium
    Patent number: 8318933
    Abstract: The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: November 27, 2012
    Assignee: Aurobindo Pharma Ltd
    Inventors: Sambhu Prasad Sarma Mallela, Narayan K. A. S. S. Garimella, Sukumar Nandi, Sunil Kumar Buridipad, Gangadhar Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for preparing rosuvastatin calcium
    Patent number: 8212034
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-iso-propyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid]calcium salt of Formula II.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process for preparation of rosuvastatin calcium field of the invention
    Patent number: 8212035
    Abstract: The present invention relates to an improved process for preparing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium of Formula (I).
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nandi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE PREPARATION OF DUTASTERIDE
    Publication number: 20120157683
    Abstract: The present invention provides an improved process for the preparation of Dutasteride (I) which comprises: (i) reacting 4-aza-5?-androst-1-en-3-one-17?-carboxylic acid (VII), Formula VII with sulfonic acid anhydride (RSO2)2O in presence of base to produce an intermediate compound of Formula (XIII), wherein R represents C1-6 alkyl, C1-6 halo alkyl, C6-10 aryl, halo aryl; (ii) condensing compound of Formula (XIII) with 2,5-bis(trifluoromethyl)aniline (III), Formula (III) in the presence or absence of a base to produce Dutasteride (I).
    Type: Application
    Filed: July 7, 2010
    Publication date: June 21, 2012
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Balanarasimha Reddy Gona, Naresh Akkina, Rami Ananta, Islam Aminul, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER
    Publication number: 20120149905
    Abstract: The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester.
    Type: Application
    Filed: August 17, 2009
    Publication date: June 14, 2012
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhara Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARING ROSUVASTATIN CALCIUM
    Publication number: 20100048899
    Abstract: The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I.
    Type: Application
    Filed: October 29, 2007
    Publication date: February 25, 2010
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Narayan K.A.S.S. Garimella, Sukumar Nandi, Sunil Kumar Buridipad, Gangadhar Bhima Shankar Nangi, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARING ROSUVASTATIN CALCIUM
    Publication number: 20100029940
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methyl-sulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid] calcium salt of Formula II
    Type: Application
    Filed: December 11, 2007
    Publication date: February 4, 2010
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM FIELD OF THE INVENTION
    Publication number: 20090312547
    Abstract: The present invention relates to an improved process for preparing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium of Formula (I).
    Type: Application
    Filed: February 4, 2008
    Publication date: December 17, 2009
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam