Patents by Inventor Sukumar Sakamuri

Sukumar Sakamuri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIPEPTIDYL PEPTIDASE IV INHIBITORS
    Publication number: 20110257164
    Abstract: Described are novel compounds of the Formula (I), their derivatives, analogs, tautomeric forms, regioisomers, stereoisomers, polymorphs, solvates, intermediates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites and prodrugs thereof. These compounds are effective in lowering blood glucose, serum insulin, free fatty acids, cholesterol, triglyceride levels; treatment of obesity, inflammation, autoimmune diseases such as multiple sclerosis, rheumatoid arthritis; treatment and/or prophylaxis of type II diabetes. These compounds are more particularly dipeptidyl peptidase (DPP IV) inhibitors.
    Type: Application
    Filed: January 7, 2010
    Publication date: October 20, 2011
    Applicant: ORCHID RESEARCH LABORATORIES LIMITED
    Inventors: Gopalan Balasubramanian, Sukumar Sakamuri, Gajendra Singh, Sivanesan Dharmalingam, Franklin Pooppady Xavier, Shridhar Narayanan, Jeyamurugan Mookkan, Jeganatha Sivakumar Balasubramanian, Agneeswari Rajalingam, Jayanarayan Kulathingal
  • Tubulysin analogues
    Patent number: 7816377
    Abstract: The invention relates to tubulysin derivatives of general formula (II), said derivatives having a cytostatic effect.
    Type: Grant
    Filed: July 9, 2003
    Date of Patent: October 19, 2010
    Assignee: R&D-Biopharmaceuticals GmbH
    Inventors: Alexander Dömling, Bernd Henkel, Barbara Beck, Katrin Illgen, Sukumar Sakamuri, Sanjay Menon
  • GLUCAGON-LIKE PROTEIN-1 RECEPTOR (GLP-1R) AGONIST COMPOUNDS
    Publication number: 20090098130
    Abstract: The present invention provides GA targeting compounds which comprise GA targeting agent-linker conjugates linked to a combining site of an antibody. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
    Type: Application
    Filed: January 4, 2008
    Publication date: April 16, 2009
    Inventors: Curt W. BRADSHAW, Sukumar Sakamuri, Yanwen Fu, Bryan Oates, Joel Desharnais, David Tumelty
  • Novel tubulysin analogues
    Publication number: 20050239713
    Abstract: The invention relates to tubulysin derivatives of general formula (II), said derivatives having a cytostatic effect.
    Type: Application
    Filed: July 9, 2003
    Publication date: October 27, 2005
    Applicant: R&D-Biopharmaceuticals Am
    Inventors: Alexander Domling, Bernd Henkel, Barbara Beck, Katrin Illgen, Sukumar Sakamuri, Sanjay Menon
  • Novel anticancer compounds
    Publication number: 20050228017
    Abstract: The present invention relates to compounds of formula (I): (I) their pharmacologically acceptable salts, or solvates and hydrates, and their prodrugs, respectively, and to pharmaceutical compositions containing the same as active ingredient. These novel compounds are especially useful in the treatment of cancer.
    Type: Application
    Filed: October 31, 2002
    Publication date: October 13, 2005
    Inventors: Sanjay Menon, Yingchun Lu, Sukumar Sakamuri, Quin-Zene Chen, Vladimir Khazak
  • 2-3-disubstituted quinuclidiness as modulators of monoamine transporters and theraperutic and diagnostic methods based thereon
    Publication number: 20050131051
    Abstract: The present invention relates to a class of compounds of formula (I) and (II): wherein R1 is hydrogen; linear or branched C1-C15 alkyl; C1-C15 alkenyl; C3-C6 cycloalkyl; mono, di, tri, tetra, penta substituted aryl or heteroaryl; COOR3; —(CH2)n-aryl; —COO—(CH2)nR3; —(CH2)n—COOR3; —C(O)R3; —C(O)NHR3; or an unsubstituted or substituted oxadiazole; and R2 is hydrogen; linear or branched C1-C15 alkyl; C1-C15 alkenyl; C3-C6 cycloalkyl; mono, di, tri, tetra, penta substituted aryl or heteroaryl; unsubstituted or substituted naphthyl; 1,3-Benzodioxole; fluorene; indole; isoquinoline; quinoline; pyridine; pyrimidine; onnthracene; or —(CH2)n-Ph; wherein the heteroaryl comprises N, O, or S, the mono or multi substituents on the aryl or heteroaryl are independently C1-C5 alkyl, C1-C5 alkenyl, H, F, Cl, Br, I, —NO2, NHR, or —OR, R is C1-C7 alkyl; R3 is C1-C5 alkyl, C1-C5 alkenyl, benzyl, substituted aryl or heteroaryl; and n=1-7.
    Type: Application
    Filed: August 21, 2001
    Publication date: June 16, 2005
    Inventors: Shaomeng Wang, Sukumar Sakamuri, Istvan Enyedey, Alan Kozikowski