Patents by Inventor Sum Chan

Sum Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250102491
    Abstract: Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques.
    Type: Application
    Filed: December 10, 2024
    Publication date: March 27, 2025
    Inventors: Changming Yang, Sum Chan
  • Publication number: 20250067758
    Abstract: A method for determining a combined amount of ?-tocopherol and ?-tocopherol in a sample by tandem mass spectrometry includes subjecting the sample to ionization under conditions suitable to produce one or more ions from the ?-tocopherol and ?-tocopherol detectable by mass spectrometry; and determining the amount of one or more of said ions by tandem mass spectrometry, wherein tandem mass spectrometry comprises fragmenting ?-tocopherol and ?-tocopherol ions having a mass to charge ratio of about 416.35±0.80 into one or more fragment ions comprising a fragment ion having a mass to charge ratio of about 151.00±0.80, wherein the amount of the one or more ions determined is related to the combined amount of ?-tocopherol and ?-tocopherol in the sample.
    Type: Application
    Filed: November 7, 2024
    Publication date: February 27, 2025
    Inventors: Sum Chan, Qibo Jiang
  • Publication number: 20250054742
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Application
    Filed: October 25, 2024
    Publication date: February 13, 2025
    Inventors: Qibo Jiang, Sum Chan, Richard E. Reitz
  • Patent number: 12196742
    Abstract: Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques.
    Type: Grant
    Filed: October 16, 2023
    Date of Patent: January 14, 2025
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Changming Yang, Sum Chan
  • Publication number: 20250002971
    Abstract: Provided are methods for determining the amount of total thiamine in a body fluid sample using liquid chromatography and mass spectrometry. Total thiamine is converted to free thiamine by treatment with an acid phosphatase prior to thiamine separation and quantification.
    Type: Application
    Filed: September 13, 2024
    Publication date: January 2, 2025
    Inventors: Sum Chan, Qibo Jiang, Richard E Reitz
  • Patent number: 12174203
    Abstract: Methods are described for measuring the amount of one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample.
    Type: Grant
    Filed: November 28, 2022
    Date of Patent: December 24, 2024
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Sum Chan, Qibo Jiang
  • Patent number: 12165861
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Grant
    Filed: September 13, 2023
    Date of Patent: December 10, 2024
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Qibo Jiang, Sum Chan, Richard E Reitz
  • Patent number: 12116617
    Abstract: Provided are methods for determining the amount of total thiamine in a body fluid sample using liquid chromatography and mass spectrometry. Total thiamine is converted to free thiamine by treatment with an acid phosphatase prior to thiamine separation and quantification.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: October 15, 2024
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Sum Chan, Qibo Jiang, Richard E. Reitz
  • Publication number: 20240243813
    Abstract: A method of improving an information transmission rate involves reducing atmospheric distortions by emitting at the same or nearly the same wavelength a reference source for adaptive optic correction and a signal source for optical communication. The reference source is brighter than the signal source and the (pulsed or continuous) reference source is emitted earlier than the (pulsed or continuous) signal source. By adjustment of the time delay between the reference source and the signal source and/or the delay time in adaptive optics control and/or apparent angular speed of the sources relative to the detecting module and/or the physical separation between the reference source and the signal source, the optical paths of a reference source beam and a signal source beam have about same wavefront distortion. The reference source beam and the signal source beam are detected in a side by side manner by detectors physically located next to each other.
    Type: Application
    Filed: May 25, 2022
    Publication date: July 18, 2024
    Applicant: THE UNIVERSITY OF HONG KONG
    Inventors: Hoi Fung CHAU, Kai Sum CHAN
  • Publication number: 20240044864
    Abstract: Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques.
    Type: Application
    Filed: October 16, 2023
    Publication date: February 8, 2024
    Inventors: Changming Yang, Sum Chan
  • Publication number: 20230420235
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Application
    Filed: September 13, 2023
    Publication date: December 28, 2023
    Inventors: Qibo Jiang, Sum Chan, Richard E Reitz
  • Patent number: 11821889
    Abstract: Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques.
    Type: Grant
    Filed: April 7, 2022
    Date of Patent: November 21, 2023
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Changming Yang, Sum Chan
  • Patent number: 11798794
    Abstract: Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5?-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: October 24, 2023
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Qibo Jiang, Sum Chan, Richard E. Reitz
  • Publication number: 20230096666
    Abstract: Methods are described for measuring the amount of one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample.
    Type: Application
    Filed: November 28, 2022
    Publication date: March 30, 2023
    Inventors: Sum CHAN, Qibo JIANG
  • Publication number: 20230086372
    Abstract: An example method for estimating a media level of a media stack in a printer includes storing a media level model correlating a picker metric of a media picker to pick media from the media stack to the media level; measuring a current picker metric when the media picker picks the media from the media stack during a print job; adding the current picker metric to a historical data set; updating the media level model by generating a regression for the historical data set; and based on the current picker metric and the updated media level model, estimating a current media level of the media stack.
    Type: Application
    Filed: September 22, 2021
    Publication date: March 23, 2023
    Inventors: Peter James Boucher, Peter James Boucher, JR., Eric Scott Collins, Roseann Lok Sum Chan
  • Patent number: 11513130
    Abstract: Methods are described for measuring the amount of one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: November 29, 2022
    Assignee: Quest Diagnostics Investment Incoporated
    Inventors: Sum Chan, Qibo Jiang
  • Publication number: 20220229041
    Abstract: Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques.
    Type: Application
    Filed: April 7, 2022
    Publication date: July 21, 2022
    Inventors: Changming Yang, Sum Chan
  • Patent number: 11300559
    Abstract: Methods are described for measuring the amount of a vitamin B2 in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying vitamin B2 in a sample utilizing on-line extraction methods coupled with tandem mass spectrometric techniques.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: April 12, 2022
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Changming Yang, Sum Chan
  • Publication number: 20210239718
    Abstract: Provided are methods for determining the amount of vitamin C in a sample using mass spectrometry. The methods generally involve ionizing vitamin C in a sample and detecting and quantifying the amount of the ion to determine the amount of vitamin C in the sample.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 5, 2021
    Inventors: Qibo Jiang, Richard E. Reitz, Sum Chan
  • Publication number: 20210096141
    Abstract: Methods are described for measuring the amount of one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying one or more of vitamin A, ?-tocopherol, and the combination of ?-tocopherol and ?-tocopherol in a sample.
    Type: Application
    Filed: December 7, 2020
    Publication date: April 1, 2021
    Inventors: Sum CHAN, Qibo JIANG