Patents by Inventor Sumana CHAKRAVARTY

Sumana CHAKRAVARTY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus and method of use for an automated mosquito salivary gland extraction device
    Patent number: 11503819
    Abstract: Systems and methods for providing a combined mosquito staging and dissection system are disclosed. The system can include a mosquito staging subsystem; a robotic pick-and-place station; and a dissection, extrusion, collection, and disposal subsystem. The subsystems can include one or more stations to provide orientation, decapitation, extrusion of salivary glands, and disposal of carcasses of the mosquitoes. The resident live sporozoites from the salivary glands can be used to produce Plasmodium SPZ-based vaccines.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: November 22, 2022
    Assignees: Sanaria Inc., The Johns Hopkins University
    Inventors: Russell H. Taylor, Gregory Chirikjian, Iulian Iordachita, Henry Phalen, Hongtao Wu, Mengdi Xu, Shengnan Lu, Michael Aaron Pozin, Jin Seob Kim, Can Kocabalkanli, Balazs Vagvolgyi, Brian K. Chirikjian, Joshua Davis, Ting Da, John S. Chirikjian, Sumana Chakravarty, Stephen Hoffman
  • Apparatus and Method of Use for an Automated Mosquito Salivary Gland Extraction Device
    Publication number: 20210045375
    Abstract: Systems and methods for providing a combined mosquito staging and dissection system are disclosed. The system can include a mosquito staging subsystem; a robotic pick-and-place station; and a dissection, extrusion, collection, and disposal subsystem. The subsystems can include one or more stations to provide orientation, decapitation, extrusion of salivary glands, and disposal of carcasses of the mosquitoes. The resident live sporozoites from the salivary glands can be used to produce Plasmodium SPZ-based vaccines.
    Type: Application
    Filed: August 17, 2020
    Publication date: February 18, 2021
    Inventors: Russell H. TAYLOR, Gregory CHIRIKJIAN, Iulian IORDACHITA, Henry PHALEN, Hongtao WU, Mengdi XU, Shengnan LU, Michael Aaron POZIN, Jin Seob KIM, Can KOCABALKANLI, Balazs VAGVOLGYI, Brian K. CHIRIKJIAN, Joshua DAVIS, Ting DA, John S. CHIRIKJIAN, Sumana CHAKRAVARTY, Stephen HOFFMAN
  • Mosquito salivary gland extraction device and methods of use
    Patent number: 10781419
    Abstract: A device and method of use for augmenting the extraction of salivary glands from Plasmodium-infected mosquitoes, where the sporozoite stage of Plasmodium primarily resides. Sporozoites are useful for research as well as for the immunogen in whole parasite vaccines for the prevention of malaria. The device and methods of use disclosed herein greatly increase the rate at which sporozoites can be harvested.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: September 22, 2020
    Assignees: Sanaria Inc., Johns Hopkins University
    Inventors: Russell H. Taylor, Amanda Canezin, Mariah Schrum, Iulian Iordachita, Gregory Chirikjian, Michelle Laskowski, Sumana Chakravarty, Stephen Hoffman
  • Mosquito Salivary Gland Extraction Device and Methods of Use
    Publication number: 20170355951
    Abstract: A device and method of use for augmenting the extraction of salivary glands from Plasmodium-infected mosquitoes, where the sporozoite stage of Plasmodium primarily resides. Sporozoites are useful for research as well as for the immunogen in whole parasite vaccines for the prevention of malaria. The device and methods of use disclosed herein greatly increase the rate at which sporozoites can be harvested.
    Type: Application
    Filed: June 13, 2017
    Publication date: December 14, 2017
    Inventors: Russell H. TAYLOR, Amanda CANEZIN, Mariah SCHRAM, lulian IORDACHITA, Gregory CHIRIKJIAN, Michelle LASKOWSKI, Sumana CHAKRAVARTY, Stephen HOFFMAN
  • Pharmaceutical compositions comprising attenuated sporozoites and glycolipid adjuvants
    Patent number: 9642909
    Abstract: Disclosed herein are pharmaceutical compositions comprising Plasmodium sporozoite-stage parasites and compatible glycolipid adjuvants useful in vaccines for preventing or reducing the risk of malaria. In particular, human host range Plasmodium and analogues of ?-galactosylceramide (?-GalCer), a ligand for natural killer T (NKT) cells, are combined in pharmaceutical compositions, which are useful as vaccines against malaria. Methods of use are also provided.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: May 9, 2017
    Assignees: Sanaria Inc., The Rockefeller University
    Inventors: Sumana Chakravarty, Stephen L. Hoffman, Moriya Tsuji
  • PHARMACEUTICAL COMPOSITIONS COMPRISING ATTENUATED PLASMODIUM SPOROZOITES AND GLYCOLIPID ADJUVANTS
    Publication number: 20160158351
    Abstract: Disclosed herein are pharmaceutical compositions comprising Plasmodium sporozoite-stage parasites and compatible glycolipid adjuvants useful in vaccines for preventing or reducing the risk of malaria. In particular, human host range Plasmodium and analogues of ?-galactosylceramide (?-GalCer), a ligand for natural killer T (NKT) cells, are combined in pharmaceutical compositions, which are useful as vaccines against malaria. Methods of use are also provided.
    Type: Application
    Filed: February 18, 2016
    Publication date: June 9, 2016
    Applicants: Sanaria Inc., The Rockefeller University
    Inventors: Sumana CHAKRAVARTY, Stephen L. HOFFMAN, Moriya TSUJI
  • Pharmaceutical compositions comprising attenuated sporozoites and glycolipid adjuvants
    Patent number: 9278125
    Abstract: Disclosed herein are pharmaceutical compositions comprising Plasmodium sporozoite-stage parasites and compatible glycolipid adjuvants useful in vaccines for preventing or reducing the risk of malaria. In particular, human host range Plasmodium and analogues of ?-galactosylceramide (?-GalCer), a ligand for natural killer T (NKT) cells, are combined in pharmaceutical compositions, which are useful as vaccines against malaria. Methods of use are also provided.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: March 8, 2016
    Assignees: SANARIA INC., THE ROCKEFELLER UNIVERSITY
    Inventors: Sumana Chakravarty, Stephen L. Hoffman, Moriya Tsuji
  • PHARMACEUTICAL COMPOSITIONS COMPRISING ATTENUATED PLASMODIUM SPOROZOITES AND GLYCOLIPID ADJUVANTS
    Publication number: 20140120138
    Abstract: Disclosed herein are pharmaceutical compositions comprising Plasmodium sporozoite-stage parasites and compatible glycolipid adjuvants useful in vaccines for preventing or reducing the risk of malaria. In particular, human host range Plasmodium and analogues of ?-galactosylceramide (?-GalCer), a ligand for natural killer T (NKT) cells, are combined in pharmaceutical compositions, which are useful as vaccines against malaria. Methods of use are also provided.
    Type: Application
    Filed: October 28, 2013
    Publication date: May 1, 2014
    Applicant: Sanaria, Inc.
    Inventors: Sumana CHAKRAVARTY, Stephen L. Hoffman, Moriya Tsuji
  • PHARMACEUTICAL COMPOSITIONS COMPRISING ATTENUATED PLASMODIUM SPOROZOITES AND GLYCOLIPID ADJUVANTS
    Publication number: 20120288525
    Abstract: Disclosed herein are pharmaceutical compositions comprising Plasmodium sporozoite-stage parasites and compatible glycolipid adjuvants useful in vaccines for preventing or reducing the risk of malaria. In particular, human host range Plasmodium and analogues of ?-galactosylceramide (?-GalCer), a ligand for natural killer T (NKT) cells, are combined in pharmaceutical compositions, which are useful as vaccines against malaria. Methods of use are also provided.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Inventors: Sumana CHAKRAVARTY, Stephen L. HOFFMAN, Moriya TSUJI